Cadherin and Integrin Regulation of Epithelial Cell Migration [PDF]
Langmuir, 2009 These studies quantified the relative effects of E-cadherin expression and homophilic ligation on the integrin-mediated motility of epithelial cells. Micropatterned proteins were used to quantitatively titrate the ligation of E-cadherin and integrin receptors in order to assess their coordinate influence on the migration velocities of MDA-MB-231 breast
Jonathan, Silvestre +2 more
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Als3 is a Candida albicans invasin that binds to cadherins and induces endocytosis by host cells. [PDF]
PLoS Biology, 2007 Candida albicans is the most common cause of hematogenously disseminated and oropharyngeal candidiasis. Both of these diseases are characterized by fungal invasion of host cells. Previously, we have found that C.
Quynh T Phan +8 more
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Dynamic interactions between E-cadherin and Ankyrin-G mediate epithelial cell polarity maintenance
Nature Communications, 2023 E-cadherin is an essential cell‒cell adhesion protein that mediates canonical cadherin-catenin complex formation in epithelial lateral membranes.
Chao Kong +11 more
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Clinical significance of epithelial-to-mesenchymal transition in laryngeal carcinoma: Its role in the different subsites [PDF]
, 2017 Background: During epithelial-to-mesenchymal transition, cancer cells lose adhesion capacity gaining migratory properties. The role of the process on prognosis has been evaluated in 50 cases of laryngeal carcinoma.
Carletti, R +7 more
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Reduced surface expression of epithelial E-cadherin evoked by interferon-gamma is Fyn kinase-dependent. [PDF]
PLoS ONE, 2012 Interferon gamma (IFNγ) is an important regulatory cytokine that can exert a pro-inflammatory effect in the gut, where it has been shown to increase epithelial permeability via disruption of the tight junctions.
David Smyth +3 more
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Sphingomyelin metabolism is involved in the differentiation of MDCK cells induced by environmental hypertonicity [PDF]
, 2015 Sphingolipids (SLs) are relevant lipid components of eukaryotic cells. Besides regulating various cellular processes, SLs provide the structural framework for plasma membrane organization.
Favale, Nicolas Octavio +4 more
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Phosphatase Regenerating Liver3 and ECadherin Expression in Epithelial Ovarian Cancer
Indonesian Journal of Obstetrics and Gynecology, 2016 Objective: To determine the expression of Phosphatase Regenerating Liver-3 (PRL-3) and E-Cadherin in the epithelial ovarian cancer on various stages and differentiation grades. Method: This was a cross-sectional study design conducted at Obstetrics
Risma Maharani +2 more
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Molecular mechanisms controlling the phenotype and the EMT/MET dynamics of hepatocyte [PDF]
, 2014 The complex spatial and paracrine relationships between the various liver histotypes are essential for proper functioning of the hepatic parenchymal cells.
Fausto N +6 more
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HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal [PDF]
, 2018 Peritoneal fibrosis is a pathological alteration of the peritoneal membrane occurring in a variety of conditions including peritoneal dialysis (PD), post-surgery adhesions and peritoneal metastases.
Battistelli, Cecilia +14 more
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Key signalling nodes in mammary gland development and cancer: the snail1-twist1 conspiracy in malignant breast cancer progression [PDF]
, 2010 Breast cancer is the most common cancer among women, and despite significant advances in diagnosing and treating it, metastatic spread of cancer cells results in a high mortality rate. Epithelial-to-mesenchymal transition (EMT) is an embryonic program in
Foubert, Ellen +2 more
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