Results 161 to 170 of about 472,049 (341)

Epitope

Nippon Shokuhin Kagaku Kogaku Kaishi, 2006
  +5 more sources

High-efficiency gene transfer by adenovirus coupled to DNA-polylysine complexes [PDF]

, 1992
Agarwal, Santosh, Birnstiel, Max L., Cotten, Matt, Curiel, David T., Hu, P.-C., Li, C.-M., Loechel, S., Wagner, Ernst   +7 more
core   +1 more source

Prevention of allergy by a recombinant multi-allergen vaccine with reduced IgE binding and preserved T cell epitopes [PDF]

, 2005
Fariba Karamloo, Peter Schmid‐Grendelmeier, Fatimah Kussebi, Mübeccel Akdiş, Maria Salagianni, Barbara R. von Beust, Andrea Reimers, Judith Zumkehr, Л. С. Солдатова, Zora Housley-Markovic, Ulrich Müller, Thomas M. Kündig, D.M. Kemeny, Michael D. Spangfort, Kurt Blaser, Cezmi A. Akdiş   +15 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Evolutionary and functional epitopes of the Spätzle protein: New insights into activation of the Toll receptor

, 2009
Yunpeng Wang, Shunyi Zhu
openalex   +2 more sources

Computational Approaches to Facilitate Epitope-Based HLA Matching in Solid Organ Transplantation [PDF]

, 2017
Kirsten Geneugelijk, Jeroen Wissing, Dirk Koppenaal, Matthias Niemann, Eric Spierings   +4 more
openalex   +1 more source

Epitop [PDF]

, 2017
H. Renz, B. Gierten
openaire   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

The impact of viral evolution and frequency of variant epitopes on primary and memory human immunodeficiency virus type 1-specific CD8+ T cell responses

, 2013
Nada M. Melhem, Kellie N. Smith, Xiao-Li Huang, Bonnie A. Colleton, Weimin Jiang, Robbie B. Mailliard, James I. Mullins, Charles R. Rinaldo   +7 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source