Results 161 to 170 of about 3,015 (181)

Decoding causal m6A: a bioinformatics roadmap for psychiatric disorders. [PDF]

Brief Bioinform
Liu S, Zhao X, Wei Z, Carr DF, Moraros J.   +4 more
europepmc   +1 more source

Epitranscriptomics in Normal and Malignant Hematopoiesis [PDF]

International Journal of Molecular Sciences, 2020
Epitranscriptomics analyze the biochemical modifications borne by RNA and their downstream influence. From this point of view, epitranscriptomics represent a new layer for the control of genetic information and can affect a variety of molecular processes
Francesco Albano, Francesco Albano, Antonella Zagaria   +2 more
exaly   +3 more sources

Recent Major Transcriptomics and Epitranscriptomics Contributions toward Personalized and Precision Medicine

Journal of Personalized Medicine, 2022
With the advent of genome-wide screening methods—beginning with microarray technologies and moving onto next generation sequencing methods—the era of precision and personalized medicine was born.
Farah R. Zahir
exaly   +2 more sources

The Regulation of RNA Modification Systems: The Next Frontier in Epitranscriptomics?

Genes, 2021
RNA modifications, long considered to be molecular curiosities embellishing just abundant and non-coding RNAs, have now moved into the focus of both academic and applied research.
Matthias Schaefer
exaly   +2 more sources

Epitranscriptomics in atherosclerosis: Unraveling RNA modifications, editing and splicing and their implications in vascular disease [PDF]

Vascular Pharmacology
Atherosclerosis remains a leading cause of morbidity and mortality worldwide, driven by complex molecular mechanisms involving gene regulation and post-transcriptional processes. Emerging evidence highlights the critical role of epitranscriptomics, the
Rosienne Farrugia, Yvan Devaux, Miron Sopić   +2 more
exaly   +4 more sources

Epitranscriptomics as a New Layer of Regulation of Gene Expression in Skeletal Muscle: Known Functions and Future Perspectives [PDF]

International Journal of Molecular Sciences, 2023
Epitranscriptomics refers to post-transcriptional regulation of gene expression via RNA modifications and editing that affect RNA functions. Many kinds of modifications of mRNA have been described, among which are N6-methyladenosine (m6A), N1 ...
Alessandra Renzini, Eleonora Maretti, Silvia Belluti   +2 more
exaly   +4 more sources

SRSF2 plays an unexpected role as reader of m5C on mRNA, linking epitranscriptomics to cancer

Molecular Cell, 2023
A common mRNA modification is 5-methylcytosine (m5C), whose role in gene-transcript processing and cancer remains unclear. Here, we identify serine/arginine-rich splicing factor 2 (SRSF2) as a reader of m5C and impaired SRSF2 m5C binding as a potential ...
Martin Bizet, Pascale Putmans, Rachel Deplus   +2 more
exaly   +2 more sources

The rise of epitranscriptomics: recent developments and future directions [PDF]

Trends in Pharmacological Sciences
The epitranscriptomics field has undergone tremendous growth since the discovery that the RNA N6-methyladenosine (m6A) modification is reversible and is distributed throughout the transcriptome.
Guo-Li Ming, Yanhong Shi, Hongjun Song
exaly   +2 more sources

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Epitranscriptomics Markers Regulate the Infection by RNA Viruses

RNA Technologies, 2021
Apostolos Zaravinos, Vassiliki Stamatopoulou   +1 more
exaly