GPR40 is a low-affinity epoxyeicosatrienoic acid receptor in vascular cells. [PDF]
J Biol Chem, 2018 Park SK +6 more
europepmc +1 more source
Astrocytic Epoxyeicosatrienoic Acid Signaling in the Medial Prefrontal Cortex Modulates Depressive-like Behaviors. [PDF]
J Neurosci, 2019 Xiong W +15 more
europepmc +1 more source
Epoxyeicosatrienoic acid analog EET-B attenuates post-myocardial infarction remodeling in spontaneously hypertensive rats. [PDF]
Clin Sci (Lond), 2019 Neckář J +14 more
europepmc +1 more source
Structural determinants of 5',6'-epoxyeicosatrienoic acid binding to and activation of TRPV4 channel. [PDF]
Sci Rep, 2017 Berna-Erro A +10 more
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14,15-epoxyeicosatrienoic acid produced by cytochrome P450s enhances neurite outgrowth of PC12 and rat hippocampal neuronal cells. [PDF]
Pharmacol Res Perspect, 2018 Oguro A, Inoue T, Kudoh SN, Imaoka S.
europepmc +1 more source
Mechanical and osmotic sensitivity of the transient receptor potential vanilloid 4 (TRPV4) channel depends on phospholipase A(2) (PLA(2)) activation and the subsequent production of the arachidonic acid metabolites, epoxyeicosatrienoic acid (EET).
Serra Pascual, Selma A., 1981- +6 more
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11,12-Epoxyeicosatrienoic acid induces vasodilator response in the rat perfused mesenteric vasculature. [PDF]
Auton Autacoid Pharmacol, 2017 Bihzad SM, Yousif MH.
europepmc +1 more source
TPPU enhanced exercise-induced epoxyeicosatrienoic acid concentrations to exert cardioprotection in mice after myocardial infarction. [PDF]
J Cell Mol Med, 2018 Guo Y +6 more
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Synthesis of cyclooxygenase metabolites of 8,9-epoxyeicosatrienoic acid (EET): 11- and 15-hydroxy 8,9-EETs. [PDF]
Org Biomol Chem, 2017 Barnych B +4 more
europepmc +1 more source
The Cytochrome P450 Slow Metabolizers CYP2C9*2 and CYP2C9*3 Directly Regulate Tumorigenesis via Reduced Epoxyeicosatrienoic Acid Production. [PDF]
Cancer Res, 2018 Sausville LN +12 more
europepmc +1 more source