Results 131 to 140 of about 2,734,900 (203)

The epoxyeicosatrienoic acid pathway enhances hepatic insulin signaling and is repressed in insulin-resistant mouse liver.

, 2015
While it is widely accepted that ectopic lipid accumulation in the liver is associated with hepatic insulin resistance, the underlying molecular mechanisms have not been well characterized.
Adamski, J., Kahle-Stephan, M., Neschen, S., Sarioglu, H., Imhof, A., Schäfer, A., Gaisbauer, T., Hauck, S.M., Ueffing, M.   +8 more
core   +1 more source

14,15-Epoxyeicosatrienoic Acid Protect Against Glucose Deprivation and Reperfusion-Induced Cerebral Microvascular Endothelial Cells Injury by Modulating Mitochondrial Autophagy via SIRT1/FOXO3a Signaling Pathway and TSPO Protein. [PDF]

Front Cell Neurosci, 2022
Qu Y, Cao J, Wang D, Wang S, Li Y, Zhu Y.   +5 more
europepmc   +1 more source

Endogenous epoxyeicosatrienoic acids

Journal of Biological Chemistry, 1989
A Karara, E Dishman, I Blair, J R Falck, J H Capdevila   +4 more
openaire   +1 more source

Epoxyeicosatrienoic acid administration or soluble epoxide hydrolase inhibition attenuates renal fibrogenesis in obstructive nephropathy.

Am J Physiol Renal Physiol, 2023
Noh MR, Jang HS, Salem FE, Ferrer FA, Kim J, Padanilam BJ.   +5 more
europepmc   +1 more source

Early Renal Vasodilator and Hypotensive Action of Epoxyeicosatrienoic Acid Analog (EET-A) and 20-HETE Receptor Blocker (AAA) in Spontaneously Hypertensive Rats. [PDF]

Front Physiol, 2021
Walkowska A, Červenka L, Imig JD, Falck JR, Sadowski J, Kompanowska-Jezierska E.   +5 more
europepmc   +1 more source

Endothelial epoxyeicosatrienoic acid release is intact in aldosterone excess

Atherosclerosis
BACKGROUND AND AIMS Endothelial dysfunction (ED) is considered to be a major driver of the increased incidence of cardiovascular disease in primary aldosteronism (PA). The functionality of the epoxyeicosatrienoic acid (EET) pathway, involving the release of beneficial endothelium-derived lipid mediators, in PA is unknown. Evidence suggests this pathway
Meng, Yao, Bilyal, Aynur, Chen, Li, Mederos Y Schnitzler, Michael, Kocabiyik, Julien, Gudermann, Thomas, Riols, Fabien, Haid, Mark, Marques, Jair G, Horak, Jeannie, Koletzko, Berthold, Sun, Jing, Beuschlein, Felix, Heinrich, Daniel A, Adolf, Christian, Reincke, Martin, Schneider, Holger   +16 more
openaire   +4 more sources

Androgen receptor promotes arachidonic acid metabolism and angiogenic microenvironment in AFP-negative hepatocellular carcinoma

Nature Communications
Alpha-fetoprotein (AFP) is a classic biomarker for hepatocellular carcinoma (HCC). AFP-positive HCC (AFP+ HCC) has been intensively investigated; however, the genomic, transcriptomic and microenvironmental characteristics of AFP-negative HCC (AFP− HCC ...
Zhilong Lin, Xiaofei Liu, Houwei Wang, Shumin Li, Ziqiang Miao, Jing Yang, Yuting Zhang, Kai Lei, Yifan Wu, Youmei Kang, Ruoyin Zheng, Zonglin Xie, Yixi Wen, Xiaoxue Ren, Chunxiao Liu, Alfred Sze-Lok Cheng, Yubin Xie, Shuling Chen, Ming Kuang, Sui Peng, Zhenwei Peng, Zihao Dai   +21 more
doaj   +1 more source

Effects of Epoxyeicosatrienoic Acid-Enhancing Therapy on the Course of Congestive Heart Failure in Angiotensin II-Dependent Rat Hypertension: From mRNA Analysis towards Functional In Vivo Evaluation. [PDF]

Biomedicines, 2021
Kala P, Miklovič M, Jíchová Š, Škaroupková P, Vaňourková Z, Maxová H, Gawrys O, Kompanowska-Jezierska E, Sadowski J, Imig JD, Falck JR, Veselka J, Červenka L, Aiglová R, Vícha M, Gloger V, Táborský M.   +16 more
europepmc   +1 more source

Epoxygenase-Derived Epoxyeicosatrienoic Acid Mediators Are Associated With Nonalcoholic Fatty Liver Disease, Nonalcoholic Steatohepatitis, and Fibrosis. [PDF]

Gastroenterology, 2020
Arvind A, Osganian SA, Sjoquist JA, Corey KE, Simon TG.   +4 more
europepmc   +1 more source

14,15-Epoxyeicosatrienoic Acid Alleviates Pathology in a Mouse Model of Alzheimer's Disease. [PDF]

J Neurosci, 2020
Chen W, Wang M, Zhu M, Xiong W, Qin X, Zhu X.   +5 more
europepmc   +1 more source