Results 81 to 90 of about 5,105 (168)

Integrated Assessment of Lipid Oxidation and Off‐Flavor Formation in Plant Protein Powders

Journal of the American Oil Chemists' Society, Volume 103, Issue 5, Page 371-386, May 2026.
Impact of residual lipids on oxylipin and off‐flavor formation in commercial plant proteins: A detailed analysis of precursor‐product relationships by GC‐FID, LC‐MS/MS, and GC‐MS. ABSTRACT The widespread adoption of plant proteins is hindered by their inherent off‐flavors, often linked to lipid oxidation products.
Fernanda Furlan Goncalves Dias, Wellington da Silva Oliveira, Stanislau Bogusz Junior, Ameer Y. Taha   +3 more
wiley   +1 more source

Adipose Triglyceride Lipase and Gpr40 Contribute to the Anti‐Contractile Effect of Perivascular Adipose Tissue

Microcirculation, Volume 33, Issue 4, May 2026.
ABSTRACT Objective Perivascular adipose tissue (PVAT) surrounds most peripheral blood vessels and exerts an anti‐contractile influence through paracrine mediators. Although numerous vasoactive factors have been identified, the mechanisms linking adipocyte metabolism to PVAT‐dependent modulation of vascular tone remain poorly defined. Because adipocytes
Miranda Hyatt, Rinaldo Rodrigues Dos Passos, Fenix A. Araujo, Emily W. Wilson, Emily W. Waigi, Tiago J. Costa, Darízy F. Silva, R. Clinton Webb, Camilla F. Wenceslau, Cameron G. McCarthy   +9 more
wiley   +1 more source

EETs modulate NF-κB signaling and alleviate STZ-induced chronic inflammation in type 2 diabetes [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Epoxyeicosatrienoic acids (EETs) have shown preventive effects against various metabolic diseases. The objective of this study was to investigate the effects and mechanisms of EETs onT2DM in rats. The rats were divided into an T2DM group and intervention
Haoyu Bai, Zhijun Guo, Ziyi Li, Chaoqun Liu, Boke Sun, Zhifeng Xie, Siriguleng Yu   +6 more
doaj   +1 more source

A perspective: PLA2G4A as drug target for vascular inflammation in Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract Anti‐amyloid therapies for Alzheimer's disease (AD) modestly slow cognitive decline but carry significant risk of amyloid‐related imaging abnormalities (ARIAs), brain swelling, and hemorrhage, particularly in apolipoprotein E ε4 carriers. Cerebral amyloid angiopathy (CAA) and vascular inflammation drive this vulnerability, highlighting the ...
Ambreen Kanwal, Bilal E. Kerman, Shaowei Wang, Kevin Camey, Boyang Li, Lisi Flores‐Aguilar, Nada Ali, Laura Beth McIntire, Chang April Shu, Stan G. Louie, Elizabeth Head, Zoe Arvanitakis, Hussein N. Yassine   +12 more
wiley   +1 more source

The effects of CYP450 inhibition on cerebrovascular control during rest and mild hypovolemia: An exploratory study in young, healthy adults

Physiological Reports
Cerebrovascular CYP450 is underexplored in humans. Twenty‐three participants (12 females) completed familiarization and two experimental visits utilizing double‐blind, randomized, crossover design.
Jacob E. Matney, Alexander A. Buelow, Chris Mixon, Sarah M. Skillett, John D. Ashley, Jiwon Song, Amir Akbari Fakhrabadi, Paige Pointer, Justin D. Sprick, Christopher D. Black, Hugo M. Pereira, J. Mikhail Kellawan   +11 more
doaj   +1 more source

Catalytic activities of mammalian epoxide hydrolases with cis and trans fatty acid epoxides relevant to skin barrier function

Journal of Lipid Research, 2018
Lipoxygenase (LOX)-catalyzed oxidation of the essential fatty acid, linoleate, represents a vital step in construction of the mammalian epidermal permeability barrier.
Haruto Yamanashi, William E. Boeglin, Christophe Morisseau, Robert W. Davis, Gary A. Sulikowski, Bruce D. Hammock, Alan R. Brash   +6 more
doaj   +1 more source

Epoxyeicosatrienoic acids, 20-hydroxyeicosatetraenoic acid, and renal microvascular function [PDF]

Prostaglandins & Other Lipid Mediators, 2013
The development of pharmacological, genetic, and biochemical tools have allowed for detailed studies to determine the contribution of cytochrome P450 (CYP) metabolites of arachidonic acid to renal microvascular function. Renal microvessels can generate CYP hydroxylase metabolites including 20-hydroxyeicosatetraenoic acid (20-HETE) and CYP epoxygenase ...
openaire   +2 more sources

CYP2C19 variants and epoxyeicosatrienoic acids in patients with microvascular angina

International Journal of Cardiology: Heart & Vasculature, 2017
Background: Categorization as a cytochrome P450 (CYP) 2C19 poor metabolizer (PM) is reported to be an independent risk factor for cardiovascular disease.
Tomonori Akasaka, Daisuke Sueta, Yuichiro Arima, Noriaki Tabata, Seiji Takashio, Yasuhiro Izumiya, Eiichiro Yamamoto, Kenichi Tsujita, Sunao Kojima, Koichi Kaikita, Ayami Kajiwara, Kazunori Morita, Kentaro Oniki, Junji Saruwatari, Kazuko Nakagawa, Seiji Hokimoto   +15 more
doaj   +1 more source

Orally active epoxyeicosatrienoic acid analogs in hypertension and renal injury. [PDF]

Adv Pharmacol, 2022
Imig JD.
europepmc   +1 more source

Epoxyeicosatrienoic Acid and Prostanoid Crosstalk at the Receptor and Intracellular Signaling Levels to Maintain Vascular Tone. [PDF]

Int J Mol Sci, 2022
Malacarne PF, Bezzenberger J, Lopez M, Warwick T, Müller N, Brandes RP, Rezende F.   +6 more
europepmc   +1 more source