Results 11 to 20 of about 2,272 (175)

Efficacy and safety of eravacycline: A meta-analysis

Journal of Global Antimicrobial Resistance, 2021
Objectives: This study was conducted to evaluate the efficacy and safety of eravacycline, a recently approved fluorocycline for treatment of complicated intra-abdominal infections (cIAIs).
Matteo Bassetti, Khalid Eljaaly, Thamer A Almangour   +2 more
exaly   +8 more sources

Clinical outcomes and safety of eravacycline in hematology: a multicenter, real-world study [PDF]

Antimicrobial Agents and Chemotherapy
Hematology patients are highly susceptible to severe bacterial infections, particularly those caused by multidrug-resistant (MDR) gram-negative pathogens, which are associated with significant morbidity and mortality.
Jun Wang, Jun Zhu, Wen Wu, Rongmu Luo, Zhengyin Liu, Zhaohui Tong, Tongwen Sun, Yingchun Xu, Depei Wu   +8 more
doaj   +3 more sources

Assessment of Eravacycline Antimicrobial Susceptibility in China During the First Year Following Regulatory Approval (2023–2024): A Real-World Study [PDF]

Microorganisms
Eravacycline, a novel fluorocycline antimicrobial, was approved by China’s National Medical Products Administration (NMPA) in March 2023; however, clinical breakpoints and real-world data on its use in China remain limited.
Qiaolian Yi, Yi Li, Menglan Zhou, Ran Jing, Minya Lu, Yingchun Xu   +5 more
doaj   +3 more sources

Eravacycline as Salvage Therapy for Severe Intra-Abdominal Infections Caused by Multidrug-Resistant Acinetobacter baumannii: A Case Series [PDF]

Antibiotics
Background/Objectives: Infections due to multidrug-resistant (MDR) Acinetobacter baumannii represent a critical challenge in modern healthcare, with limited therapeutic options.
Marcello Trizzino, Giulio D’Agati, Luca Pipitò, Claudia Conti, Rossella Petrantoni, Raffaella Rubino, Antonio Anastasia, Sofia Urso, Irene Ganci, Maria Cappello, Antonio Cascio   +10 more
doaj   +3 more sources

Real-world use of eravacycline for the treatment of mono- and polymicrobial infections involving Enterobacterales [PDF]

Microbiology Spectrum
Bacterial species in the Enterobacterales order are commonly encountered causative organisms in hospital-acquired infections. Furthermore, the incidence of carbapenem-resistant Enterobacterales (CRE) is a growing threat worldwide. Eravacycline (ERV) is a
Sean R. Van Helden, Ashlan J. Kunz Coyne, Sara Alosaimy, Abdalhamid M. Lagnf, Kyle C. Molina, S. Lena Kang-Birken, Kimberly C. Claeys, Mark Biagi, Justin Andrade, Alaina DeKerlegand, Melanie Rae Schrack, Tristan Gore, Madeline A. King, Benjamin M. Pullinger, Serina Tart, Athena L. V. Hobbs, Jazmin Agee, Nicholson B. Perkins, Michael P. Veve, Reese Cosimi, Shelbye R. Herbin, Bruce M. Jones, Amy K. Feehan Curley, Chloe Judd, Mohammed Al Musawa, Michael J. Rybak   +25 more
doaj   +3 more sources

Resistance of Gram-Negative Bacteria to Eravacycline: A Systematic Review of Data from In Vitro Studies [PDF]

Pathogens
Introduction: Eravacycline is a new fluorocycline antibiotic with a broad spectrum of antimicrobial activity approved for the treatment of patients with complicated intra-abdominal infections.
Matthew E. Falagas, Laura T. Romanos, Dimitrios S. Kontogiannis, Charalampos Filippou, Drosos E. Karageorgopoulos   +4 more
doaj   +4 more sources

Evaluating the Efficacy of Eravacycline and Omadacycline against Extensively Drug-Resistant Acinetobacter baumannii Patient Isolates

Antibiotics, 2022
For decades, the spread of multidrug-resistant (MDR) Acinetobacter baumannii has been rampant in critically ill, hospitalized patients. Traditional antibiotic therapies against this pathogen have been failing, leading to rising concerns over management ...
Manas S. Deolankar, Rachel A. Carr, Rebecca Fliorent, Sean Roh, Henry Fraimow, Valerie J. Carabetta   +5 more
doaj   +2 more sources

Stability indicating RP-HPLC method for quantification of Eravacycline and its impurities in Eravacycline for injection [PDF]

Journal of Chemical Health Risks, 2023
The main aim and objective of the research work is to develop an effective, sensitive, economical and simple reverse phase HPLC method for quantification of Eravacycline and its impurities in Eravacycline parenteral dosage form.
P.Venkata Prabhakara Rao, Syed Mastan Ali, P. Bharath, D.Ramachandran
core   +3 more sources

In Vitro Activity of Eravacycline against Carbapenemase-Producing Gram-Negative Bacilli Clinical Isolates in Central Poland

Biomedicines, 2023
Eravacycline is a novel antibiotic of the tetracycline class with activity against a broad spectrum of clinically significant bacteria, including multi-drug-resistant organisms. For this reason, it may be an alternative to treating critical infections of
Małgorzata Brauncajs, Filip Bielec, Anna Macieja, Dorota Pastuszak-Lewandoska   +3 more
doaj   +2 more sources

In vitro activity of eravacycline, a novel synthetic halogenated tetracycline, against the malaria parasite Plasmodium falciparum

Journal of Global Antimicrobial Resistance, 2021
Objectives: Eravacycline is a novel synthetic halogenated tetracycline derivative with a broad antibacterial spectrum. Antibiotics, including tetracyclines, have been used for prophylaxis and, more rarely, for the treatment of malaria for several decades.
Erik Koehne, Andrea Kreidenweiss, Bayode Romeo Adegbite, Rella Zoleko Manego, Matthew B.B. McCall, Ghyslain Mombo-Ngoma, Ayola Akim Adegnika, Sélidji Todagbé Agnandji, Benjamin Mordmüller, Jana Held   +9 more
doaj   +2 more sources