Results 11 to 20 of about 3,777 (166)
Rapid detection of ERG11 polymorphism associated azole resistance in Candida tropicalis.
PLoS ONE, 2021 Increasing reports of azole resistance in Candida tropicalis, highlight the development of rapid resistance detection techniques. Nonsynonymous mutations in the lanosterol C14 alpha-demethylase (ERG11) gene is one of the predominant mechanisms of azole ...
Saikat Paul +6 more
doaj +4 more sources
Candida tropicalis distribution and drug resistance is correlated with ERG11 and UPC2 expression [PDF]
Antimicrobial Resistance and Infection Control, 2021 Background Candida tropicalis (C. tropicalis) is an important opportunistic pathogenic Candida species that can cause nosocomial infection. In this study, we analyzed the distribution and drug susceptibility of C.
Dan Wang +5 more
doaj +4 more sources
Expression of ERG11, ERG3, MDR1 and CDR1 genes in Candida tropicalis
Biomédica: revista del Instituto Nacional de Salud, 2023 Introduction. Drug resistance to azoles is a growing problem in the Candida genus. Objective. To analyze molecularly the genes responsible for fluconazole resistance in Candida tropicalis strains. Materials and methods. Nineteen strains, with and without
Ana Elisa Rojas +3 more
doaj +3 more sources
Azole Resistance and ERG11 Mutation in Clinical Isolates of Candida tropicalis
Journal of FungiWe investigated the molecular mechanisms underlying azole resistance in seven Candida tropicalis isolates that caused candidemia and candiduria in Paraná, Brazil (2016–2022).
Adriele Celine Siqueira +10 more
doaj +3 more sources
Infection and Drug Resistance, 2022 Arome Solomon Odiba,1,2 Olanrewaju Ayodeji Durojaye,3– 5 Ifeoma Maureen Ezeonu,6 Anthony Christian Mgbeahuruike,7 Bennett Chima Nwanguma1,2 1Department of Biochemistry, Faculty of Biological Sciences, University of Nigeria, Nsukka, Enugu State, 410001 ...
Odiba AS +4 more
doaj +3 more sources
An Erg11 lanosterol 14-α-demethylase-Arv1 complex is required for Candida albicans virulence.
PLoS ONE, 2020 Azole resistant fungal infections remain a health problem for the immune compromised. Current therapies are limited due to rises in new resistance mechanisms.
Michelle L Villasmil +4 more
doaj +3 more sources
Universal PCR assays to detect Candida FKS and ERG11 mutations
International Journal of Infectious DiseasesIntroduction: The emergence of antifungal resistance in Candida species presents significant challenges in managing infections, particularly among immunocompromised patients.
Dr Yuk Yam Cheung +4 more
doaj +2 more sources
Сибирский онкологический журнал, 2022 Relevance. The global trend of rapid increase in resistance to antifungal drugs due to multiple factors, dictates the need for continuous monitoring of taxonomic structure and susceptibility of nosocomial pathogens, causing invasive fungal infections ...
N. S. Bagirova +6 more
doaj +1 more source
ERG11 Gene Variability and Azole Susceptibility in Malassezia pachydermatis
Mycopathologia, 2022 AbstractMalassezia pachydermatis is part of the normal skin microbiota of various animal species but under certain circumstances becomes an opportunistic pathogen producing otitis and dermatitis. Commonly these Malassezia diseases are effectively treated using azoles. However, some cases of treatment failure have been reported. Alterations in the ERG11
Leyna Díaz +3 more
openaire +3 more sources
Extensive ERG11 mutations associated with fluconazole-resistant Candida albicans isolated from HIV-infected patients [PDF]
Current Medical Mycology, 2019 Background and Purpose: Azoles are preferred antifungal agents given their inexpensiveness, limited toxicity, and potentiality of oral administration.
Sony Paul +2 more
doaj +1 more source