Results 91 to 100 of about 119,648 (139)

Targeting TMED4 enhances CD8⁺ T cell function and CAR T cell efficacy in solid tumors through the IRE1α-autophagy axis. [PDF]

Sci Adv
Wang H, Shi L, Jiang K, Wu S, Jiang Z, Tao Y, Li J, Li X, Liu J, Ni J, Wu EJ, Wu SJ, Chen G, Qin M, Xu L, Lai CH, Aicher A, Ye Y, Heeschen C, Cao YJ, Wu X.   +20 more
europepmc   +1 more source

Endoplasmic Reticulum Stress-Induced Endothelial Cell Pyroptosis Contributes to Pulmonary Vascular Remodeling and Pulmonary Arterial Hypertension via IRE1α/Caspase-3/GSDME Pathway. [PDF]

J Am Heart Assoc
Luo XY, Li XC, Fu X, Tian YY, Li XY, Zhang Z, Chen AF.   +6 more
europepmc   +1 more source

Role of the IRE1α-XBP1 Axis in IgE-Dependent Activation of Mast Cells. [PDF]

Int J Mol Sci
Kouda H, Nagata K, Saito R, Nishiyama C.
europepmc   +1 more source

Proteomic Profiling Reveals HECTD4-dependent Regulation of Protein Ubiquitination and Signaling Pathways in Prostate Cancer. [PDF]

Cancer Genomics Proteomics
Takashima Y, Tanaka M, Yoshii K, Yagi T, Miyagawa-Hayashino A, Tashiro K.   +5 more
europepmc   +1 more source

SPLiCR-seq: A CRISPR-Based Screening Platform for RNA splicing Identifies Novel Regulators of IRE1α-XBP1 Signaling Under ER Stress. [PDF]

Nat Commun
Ying Q, Chen Y, Shen L, Xu Y, Tian R.
europepmc   +1 more source

Emerging role of lncRNA TP53TG1 as a tumor regulator and biomarker in human malignancies. [PDF]

Discov Oncol
Wang B, Yu T, Luo L, Tang W, Zhang H.
europepmc   +1 more source

Myrrh ameliorates endometriosis by enhancing ER stress-related apoptotic cell death. [PDF]

Exp Ther Med
Kim BS, Cho M, Han JH, Jin JS, Bae SJ, Jo Y, Ryu D, Joo Y, Kim SB, Joo J, Kim I, Ha KT.   +11 more
europepmc   +1 more source

Targeting the IRE1α-XBP1 signaling axis impairs tumor growth and promotes myogenic differentiation in rhabdomyosarcoma. [PDF]

Commun Biol
Vuong AT, Joshi AS, Ho PT, Tomaz da Silva M, Guo B, Trivedi MV, Kumar A.   +6 more
europepmc   +1 more source

Targeting the ER stress sensor IRE1 protects the liver from fibrosis through the downregulation of the proteostasis factor P4HB/PDIA1. [PDF]

Hepatology
Hazari Y, Habbouche L, Garcia Lopez VA, Urra H, Diaz J, Tamburini G, Milani M, Durand S, Aprahamian F, Baxter R, Huang M, Dong XC, Gonzalez-Rojas L, Francisco SJ, Tapia-Dufey I, Vihinen H, Ratziu V, Foufelle F, Hengstler JG, Jokitalo E, Maiers JL, Plate L, Kroemer G, Bailly-Maitre B, Hetz C.   +24 more
europepmc   +1 more source

Aberrant GRP78 Phase Transition Sustains Endothelial IRE1α Signaling and Drives Blood-Brain Barrier Failure in Cerebral Amyloid Angiopathy. [PDF]

Adv Sci (Weinh)
Zheng H, Li Q, Luo H, Yuan Y, Zhang N, Lu Y, Duan S, Zhong J, Zhang H, Liu C, Zhang Y, Zhao W, Song Y, Wang T, Yan S, Li Y, Liu H, Gao Y, Xia Z, Xu Y.   +19 more
europepmc   +1 more source