Results 91 to 100 of about 1,400 (161)
Simvastatin, a Novel Stimulator of Eryptosis, the Suicidal Erythrocyte Death
Background/Aims: The 3-hydroxy-3-methyl-glutaryl-Coenzyme A (HMG-CoA) reductase inhibitor simvastatin has been shown to trigger apoptosis of several cell types. The substance has thus been proposed as an additional treatment of malignancy.
Abdulla Al Mamun Al Mamun Bhuyan +4 more
doaj +1 more source
The apoptotic process of erythrocytes is known as eryptosis, and is characterized by phosphatidylserine (PS) expression on the outer membrane. PS-positive erythrocytes are increased in sepsis, and PS is believed to facilitate coagulation of erythrocytes ...
Hui Zhong +7 more
doaj +1 more source
Enhanced Eryptosis Following Exposure to Carnosic Acid
Background/Aims: The phenolic abietane diterpene component of rosemary and sage, carnosic acid, may either induce or inhibit apoptosis of nucleated cells. The mechanisms involved in the effects of carnosic acid include altered mitochondrial function and gene expression.
Katja Stockinger +4 more
openaire +3 more sources
Shikonin, the most important component of Lithospermum erythrorhizon, has previously been shown to exert antioxidant, anti-inflammatory, antithrombotic, antiviral, antimicrobial and anticancer effects.
Adrian Lupescu +3 more
doaj +1 more source
Programmed Erythrocyte Death Following in Vitro Treosulfan Treatment
Background/Aims: The cytotoxic drug Treosulfan is clinically used for the treatment of malignancy. A common side effect of Treosulfan treatment is anemia. Treosulfan is at least partially effective by triggering apoptosis of tumor cells.
Thomas Peter +5 more
doaj +1 more source
Breakdown of Phosphatidylserine Asymmetry Following Treatment of Erythrocytes with Lumefantrine
Background: Lumefantrine, a commonly used antimalarial drug, inhibits hemozoin formation in parasites. Several other antimalarial substances counteract parasitemia by triggering suicidal death or eryptosis of infected erythrocytes.
Kousi Alzoubi +5 more
doaj +1 more source
071 | Decoding eryptosis: human red blood cells response to xenobiotic-induced stress
Eryptosis is the programmed death of human red blood cells and shares several key features with apoptosis of nucleated cells. This physiological process plays an important role in maintaining erythrocyte homeostasis by ensuring the timely removal of ...
Società Italiana di Biologia Sperimentale
doaj

