Results 81 to 90 of about 1,847 (171)

Enhanced Eryptosis Following Auranofin Exposure

Cellular Physiology and Biochemistry, 2015
Background/Aims: The antiinflammatory, antimicrobial and anticancer drug auranofin has previously been shown to trigger apoptosis, the suicidal death of nucleated cells. Side effects of the drug include anaemia. At least in theory the anaemia could result from stimulation of suicidal death of erythrocytes or eryptosis, which involves cell shrinkage and
Kousi Alzoubi, Jasmin Egler, Majed Abed, Florian Lang   +3 more
openaire   +3 more sources

Stimulated Suicidal Erythrocyte Death in Arteritis

Cellular Physiology and Biochemistry, 2016
Background/Aims: Arteritis is an inflammatory disease of the vascular wall leading to ischemia and vascular occlusion. Complications of arteritis include anemia, which could, at least in theory, result from suicidal erythrocyte death or eryptosis, which ...
Rosi Bissinger, Daniela S. Kempe-Teufel, Sabina Honisch, Syed M. Qadri, Elko Randrianarisoa, Hans-Ulrich Häring, Jörg Henes, Florian Lang   +7 more
doaj   +1 more source

Cell Death Mechanisms Produced by Carbon‐Based Nanoparticles

Journal of Nanotechnology, Volume 2025, Issue 1, 2025.
Using carbon‐based nanoparticles, such as diamond, graphite, fullerene, and nanotubes, has increased their research as possible strategies for drug delivery to control diseases, especially cancer. However, because these materials, when interacting with the living environment, release substances that are capable of inducing cell death by themselves, it ...
Santos-Adriana Martel-Estrada, Claudia-Lucía Vargas-Requena, Josue-Itan Sifuentes-Chavarría, Maileth-Yoelis Yepes-Mendoza, Daniel-Santiago Palacio-Castillo, Florinda Jimenez-Vega, Imelda Olivas-Armendáriz, Luis Jesús Villarreal-Gómez   +7 more
wiley   +1 more source

Prolonged Survival of Neutrophils Induced by Tumor‐Derived G‐CSF/GM‐CSF Promotes Immunosuppression and Progression in Laryngeal Squamous Cell Carcinoma

Advanced Science, Volume 11, Issue 46, December 11, 2024.
This study elucidates a novel mechanism whereby tumor‐derived G‐CSF and GM‐CSF induce delayed neutrophil apoptosis by activating the PI3K‐AKT signaling pathway. Delayed neutrophil apoptosis can facilitate the accumulation of immunosuppressive CXCR4+ neutrophils and impair CD8+ T cell immunity.
Xiaoke Zhu, Yu Heng, Jingyu Ma, Duo Zhang, Di Tang, Yangyang Ji, Changding He, Hanqing Lin, Xuping Ding, Jian Zhou, Lei Tao, Liming Lu   +11 more
wiley   +1 more source

Mechanisms of red cell turnover (Eryptosis) [PDF]

Title: Mechanisms of Red Cell Turnover (Eryptosis).Author: Kris Patrick JeremyA thesis submitted in partial fulfilment of the requirements of the University of the West of England, Bristol for the degree of Doctor of Philosophy.When CD47 is ligated with ...
Jeremy, Kris P.
core  

Impact of Cyclin-Dependent Kinase CDK4 Inhibition on Eryptosis [PDF]

, 2015
Background/Aims: The cyclin-dependent kinase 4 (CDK4) participates in the regulation of apoptosis of nucleated cells by altering transcriptional regulation of genes governing cell proliferation and cell death.
Lang, F., Lang, E., Anand Rotte, Syed M. Qadri, Qadri, S.M., Mehrdad Ghashghaeinia, Adrian Lupescu, Elisabeth Lang, Zelenak, C., Rosi Bissinger, Florian Lang, Lupescu, A., Matthias Eberhard, Ghashghaeinia, M., Christine Zelenak, Eberhard, M., Bissinger, R., Rotte, A.   +17 more
core   +1 more source

Effect of Thioridazine on Erythrocytes

Toxins, 2013
Background: Thioridazine, a neuroleptic phenothiazine with antimicrobial efficacy is known to trigger anemia. At least in theory, the anemia could result from stimulation of suicidal erythrocyte death or eryptosis, which is characterized by cell ...
Majed Abed, Florian Lang, Caterina Faggio, Markus Arnold, Rosi Bissinger, Elisabeth Lang, Paola Modicano   +6 more
doaj   +1 more source

Bile Acid-Induced Suicidal Erythrocyte Death

Cellular Physiology and Biochemistry, 2016
Background/Aims: In nucleated cells, bile acids may activate cation channels subsequently leading to entry of Ca2+. In erythrocytes, increase of cytosolic Ca2+ activity triggers eryptosis, the suicidal death of erythrocytes characterized by ...
Elisabeth Lang, Vitaly I. Pozdeev, Sergios Gatidis, Syed M. Qadri, Dieter Häussinger, Ralf Kubitz, Diran Herebian, Ertan Mayatepek, Florian Lang, Karl S. Lang, Philipp A. Lang   +10 more
doaj   +1 more source

Association between vitamin D status and eryptosis : results from the German National Cohort study [PDF]

Vitamin D, besides its classical effect on mineral homeostasis and bone remodeling, can also modulate apoptosis. A special form of apoptosis termed eryptosis appears in erythrocytes.
Bürkner, Paul-Christian, Kluttig, Alexander, Stangl, Gabriele I., Föller, Michael, Hirche, Frank, Ewendt, Franz, Mikolajczyk, Rafael, Ludwig-Kraus, Beatrice, Wätjen, Wim, Kühn, Julia, Schmitt, Marvin, Kraus, Frank B.   +11 more
core   +1 more source

Stimulation of Suicidal Erythrocyte Death by Phosphatase Inhibitor Calyculin A

Cellular Physiology and Biochemistry, 2016
Background/Aims: The serine/threonine protein phosphatase 1 and 2a inhibitor Calyculin A may trigger suicidal death or apoptosis of tumor cells. Similar to apoptosis of nucleated cells, erythrocytes may enter eryptosis, the suicidal erythrocyte death ...
Mustafa Almasry, Mohamed Jemaà, Morena Mischitelli, Caterina Faggio, Florian Lang   +4 more
doaj   +1 more source