Results 81 to 90 of about 2,020 (175)
Enhanced Eryptosis Following Auranofin Exposure
Cellular Physiology and Biochemistry, 2015 Background/Aims: The antiinflammatory, antimicrobial and anticancer drug auranofin has previously been shown to trigger apoptosis, the suicidal death of nucleated cells. Side effects of the drug include anaemia. At least in theory the anaemia could result from stimulation of suicidal death of erythrocytes or eryptosis, which involves cell shrinkage and
Kousi Alzoubi +3 more
openaire +3 more sources
Cell Death Mechanisms Produced by Carbon‐Based Nanoparticles
Journal of Nanotechnology, Volume 2025, Issue 1, 2025.Using carbon‐based nanoparticles, such as diamond, graphite, fullerene, and nanotubes, has increased their research as possible strategies for drug delivery to control diseases, especially cancer. However, because these materials, when interacting with the living environment, release substances that are capable of inducing cell death by themselves, it ...
Santos-Adriana Martel-Estrada +7 more
wiley +1 more source
, 2013 RBC (A, R1) were incubated at 37°C for 4 h at 2% hematocrit in presence (gray) or absence (black line) of ionomycin (1 µM) and, then, induction of eryptosis was verified by forward scatter measurement (B) and annexin V-PE staining (C).
Paulo Renato Rivas Totino (341334) +2 more
core +1 more source
Oxysterol Mixture in Hypercholesterolemia-Relevant Proportion Causes Oxidative Stress-Dependent Eryptosis [PDF]
, 2014 Background/Aims: Oxysterol activity on the erythrocyte (RBC) programmed cell death (eryptosis) had not been studied yet. Effects of an oxysterol mixture in hyper-cholesterolemic-relevant proportion, and of individual compounds, were investigated on RBCs ...
Antonio Cilla +11 more
core +1 more source
Effect of Thioridazine on Erythrocytes
Toxins, 2013 Background: Thioridazine, a neuroleptic phenothiazine with antimicrobial efficacy is known to trigger anemia. At least in theory, the anemia could result from stimulation of suicidal erythrocyte death or eryptosis, which is characterized by cell ...
Majed Abed +6 more
doaj +1 more source
Bile Acid-Induced Suicidal Erythrocyte Death
Cellular Physiology and Biochemistry, 2016 Background/Aims: In nucleated cells, bile acids may activate cation channels subsequently leading to entry of Ca2+. In erythrocytes, increase of cytosolic Ca2+ activity triggers eryptosis, the suicidal death of erythrocytes characterized by ...
Elisabeth Lang +10 more
doaj +1 more source
Stimulation of Suicidal Erythrocyte Death by Phosphatase Inhibitor Calyculin A
Cellular Physiology and Biochemistry, 2016 Background/Aims: The serine/threonine protein phosphatase 1 and 2a inhibitor Calyculin A may trigger suicidal death or apoptosis of tumor cells. Similar to apoptosis of nucleated cells, erythrocytes may enter eryptosis, the suicidal erythrocyte death ...
Mustafa Almasry +4 more
doaj +1 more source
Triggering of Eryptosis, the Suicidal Erythrocyte Death, by Perifosine
, 2017 Background/Aims: The alkylphospholipid perifosine is used for the treatment of malignancy. The substance is effective by triggering suicidal tumor cell death or apoptosis. Side effects of perifosine include anemia.
Florian Lang, Jasmin Egler
core +2 more sources
Simvastatin, a Novel Stimulator of Eryptosis, the Suicidal Erythrocyte Death
Cellular Physiology and Biochemistry, 2017 Background/Aims: The 3-hydroxy-3-methyl-glutaryl-Coenzyme A (HMG-CoA) reductase inhibitor simvastatin has been shown to trigger apoptosis of several cell types. The substance has thus been proposed as an additional treatment of malignancy.
Abdulla Al Mamun Al Mamun Bhuyan +4 more
doaj +1 more source
Journal of Pharmacological Sciences, 2018 The apoptotic process of erythrocytes is known as eryptosis, and is characterized by phosphatidylserine (PS) expression on the outer membrane. PS-positive erythrocytes are increased in sepsis, and PS is believed to facilitate coagulation of erythrocytes ...
Hui Zhong +7 more
doaj +1 more source