Results 61 to 70 of about 1,400 (161)

Carmustine-Induced Phosphatidylserine Translocation in the Erythrocyte Membrane

Toxins, 2013
The nitrosourea alkylating agent, carmustine, is used as chemotherapeutic drug in several malignancies. The substance triggers tumor cell apoptosis. Side effects of carmustine include myelotoxicity with anemia.
Kashif Jilani, Florian Lang
doaj   +1 more source

Eryptosis in polycythemia vera and essential thrombocythemia*

Postępy Higieny i Medycyny Doświadczalnej, 2020
Aim: Polycythemia vera (PV) and essential thrombocythemia (ET) are Philadelphia–negative myeloproliferative neoplasms with documented apoptosis impairment at the level of hematopoietic stem cell. However, so far no study has evaluated apoptosis of circulating blood neoplastic cells, including the suicidal death of erythrocytes – eryptosis.
Kopka, Paweł, Bliźniewska, Katarzyna, Treliński, Jacek, Chojnowski, Krzysztof, Sicińska, Paulina, Duchnowicz, Piotr, Bukowska, Bożena   +6 more
openaire   +3 more sources

Red blood cell endothelial nitric oxide synthase: A major player in regulating cardiovascular health

British Journal of Pharmacology, Volume 183, Issue 1, Page 40-56, January 2026.
Abstract Red blood cells (RBCs) have traditionally been seen as simple carriers of gases and nutrients in the body. One important non‐canonical function of RBCs in the cardiovascular system is the regulation of nitric oxide (NO) metabolism. It has been shown that RBCs can scavenge NO, transport NO metabolites and produce NO in hypoxic conditions ...
Anthea LoBue, Sophia K. Heuser, Marla Lindemann, Junjie Li, Masudur Rahman, Malte Kelm, Johannes Stegbauer, Miriam M. Cortese‐Krott   +7 more
wiley   +1 more source

Indoxyl Sulfate, a Uremic Toxin, Stimulates Reactive Oxygen Species Production and Erythrocyte Cell Death Supposedly by an Organic Anion Transporter 2 (OAT2) and NADPH Oxidase Activity-Dependent Pathways

Toxins, 2018
It is hypothesized that the uremic toxin indoxyl sulfate (IS) plays a role in the pathogenesis of renal anemia. To further explore that hypothesis, we examined the effects of IS on reactive oxygen species (ROS) production, levels of reduced glutathione ...
Gabriela Ferreira Dias, Natalia Borges Bonan, Thiago Maass Steiner, Sara Soares Tozoni, Silvia Rodrigues, Lia Sumie Nakao, Viktoriya Kuntsevich, Roberto Pecoits Filho, Peter Kotanko, Andréa N. Moreno-Amaral   +9 more
doaj   +1 more source

Eryptosis: An Erythrocyte’s Suicidal Type of Cell Death [PDF]

BioMed Research International, 2018
Erythrocytes play an important role in oxygen and carbon dioxide transport. Although erythrocytes possess no nucleus or mitochondria, they fulfil several metabolic activities namely, the Embden-Meyerhof pathway, as well as the hexose monophosphate shunt.
Lisa Repsold, Anna Margaretha Joubert
openaire   +3 more sources

Prognostic Biomarkers for Predicting Decompensation in Alcoholic and Nonalcoholic Patients With Compensated Cirrhosis: An Umbrella Review

Biochemistry Research International, Volume 2026, Issue 1, 2026.
Introduction Compensated cirrhosis carries a significant risk of progression to decompensation, which substantially worsens prognosis. Accurate prediction of decompensation events is critical for guiding surveillance, optimizing intervention timing, and improving patient outcomes.
Kristina Baktikulova, Saulesh Kurmangaliyeva, Amin Tamadon, Kairat Kurmangaliyev, Nadiar M. Mussin, Ramazon Safarzoda Sharoffidin, Jurandir Fernando Comar   +6 more
wiley   +1 more source

Vitamin C Inhibits Aggravated Eryptosis by Hydrogen Peroxide in Glucose-6-Phosphated Dehydrogenase Deficiency

Cellular Physiology and Biochemistry, 2016
Background/Aims: The study was aimed to investigate if vitamin C could exert protective effects on development of eryptosis caused by glucose-6-phosphate dehydrogenase (G6PD) deficiency and hydrogen peroxide. Methods: Isolated erythrocytes with different
Feng Shan, Rui Yang, Tiemei Ji, Fengjun Jiao   +3 more
doaj   +1 more source

Stimulation of Erythrocyte Membrane Blebbing by Naproxen Sodium

Dose-Response, 2020
Naproxen sodium is a nonsteroidal anti-inflammatory drug (NSAID) having antipyretic and analgesic properties, mainly used for the treatment of rheumatoid arthritis and osteoarthritis.
Sajida Ilyas, Kashif Jilani, Muhammad Sikandar, Saba Siddiq, Muhammad Riaz, Ayesha Naveed, Ismat Bibi, Haq Nawaz, Muhammad Irfan, Asma Asghar   +9 more
doaj   +1 more source

Toxic Evaluations of Calea phyllolepis Extracts Standardized on 6‐epi‐β‐Verbesinol Coumarate and Its In Silico Prediction of the Toxicity

Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.
In vivo and in silico toxicological effects of Calea phyllolepis extracts Standardized on 6‐epi‐β‐Verbesinol Coumarate. ABSTRACT Medicinal plants are traditionally used in folk medicine. Still, there is a misconception about the safety/efficacy of natural treatments, which results in few studies on the toxic, genotoxic, and mutagenic potential of ...
Suele Bierhals Vencato, Guilherme Borsoi, Cleverson Feistel, Mariele Feiffer Charão, Angélica Rocha Joaquim, Jaqueline Nascimento Picada, Alexandre de Barros Falcão Ferraz   +6 more
wiley   +1 more source

Eryptosis as an Underlying Mechanism in Systemic Lupus Erythematosus-Related Anemia

Cellular Physiology and Biochemistry, 2016
Background: The progression of systemic lupus erythematosus (SLE) leads to anemia in patients, adversely affecting prognosis. The diverse causes of anemia may include excessive eryptosis or premature suicidal erythrocyte death characterized by cell ...
Peipei Jiang, Maohong Bian, Wenjuan Ma, Chunqiu Liu, Peng Yang, Bangqiang Zhu, Yuanhong Xu, Meijuan Zheng, Jinpin Qiao, Zongwen Shuai, Xueyong Zhou, Dake Huang   +11 more
doaj   +1 more source