Results 61 to 70 of about 1,847 (171)

Eryptosis [PDF]

, 2019
Tato bakalářská práce popisuje zánik erytrocytů eryptózou, ale i jiné způsoby zániku červených krvinek. V úvodní části jsou stručně popsány obecné vlastnosti erytrocytů, stavba jejich buněčné membrány a vznik erytrocytů (= erytropoéza).
Nováková, Zuzana
core  

Carmustine-Induced Phosphatidylserine Translocation in the Erythrocyte Membrane

Toxins, 2013
The nitrosourea alkylating agent, carmustine, is used as chemotherapeutic drug in several malignancies. The substance triggers tumor cell apoptosis. Side effects of carmustine include myelotoxicity with anemia.
Kashif Jilani, Florian Lang
doaj   +1 more source

Indoxyl Sulfate, a Uremic Toxin, Stimulates Reactive Oxygen Species Production and Erythrocyte Cell Death Supposedly by an Organic Anion Transporter 2 (OAT2) and NADPH Oxidase Activity-Dependent Pathways

Toxins, 2018
It is hypothesized that the uremic toxin indoxyl sulfate (IS) plays a role in the pathogenesis of renal anemia. To further explore that hypothesis, we examined the effects of IS on reactive oxygen species (ROS) production, levels of reduced glutathione ...
Gabriela Ferreira Dias, Natalia Borges Bonan, Thiago Maass Steiner, Sara Soares Tozoni, Silvia Rodrigues, Lia Sumie Nakao, Viktoriya Kuntsevich, Roberto Pecoits Filho, Peter Kotanko, Andréa N. Moreno-Amaral   +9 more
doaj   +1 more source

Hypomorphic ATP11c is a novel regulator of decreased efficacy of transfused red blood cells in humans and mice

HemaSphere, Volume 10, Issue 1, January 2026.
Abstract Chronic red blood cell (RBC) transfusion sustains patients with diverse hematologic disorders, but repeated transfusion leads to iron overload and alloimmunization. Reducing transfusion burden requires identifying donor units that circulate more effectively after storage, yet determinants of this variability remain incompletely defined.
James C. Zimring, Ariel M. Hay, Monika Dzieciatkowska, Daniel Stephenson, Zachary B. Haiman, Steven Kleinman, Philip J. Norris, Michael P. Busch, Nareg Roubinian, Elisa Fermo, Paola Bianchi, Gregory R. Keele, Grier P. Page, Angelo D'Alessandro   +13 more
wiley   +1 more source

Estramustine-Induced Suicidal Erythrocyte Death

Cellular Physiology and Biochemistry, 2013
Background: The nitrogen mustard derivative of estradiol-17β-phosphate estramustine is used for the treatment of prostate cancer. Estramustine may trigger suicidal death of cancer cells. Side effects of estramustine include anemia.
Rosi Bissinger, Paola Modicano, Leonie Frauenfeld, Elisabeth Lang, Janin Jacobi, Caterina Faggio, Florian Lang   +6 more
doaj   +1 more source

Red blood cell endothelial nitric oxide synthase: A major player in regulating cardiovascular health

British Journal of Pharmacology, Volume 183, Issue 1, Page 40-56, January 2026.
Abstract Red blood cells (RBCs) have traditionally been seen as simple carriers of gases and nutrients in the body. One important non‐canonical function of RBCs in the cardiovascular system is the regulation of nitric oxide (NO) metabolism. It has been shown that RBCs can scavenge NO, transport NO metabolites and produce NO in hypoxic conditions ...
Anthea LoBue, Sophia K. Heuser, Marla Lindemann, Junjie Li, Masudur Rahman, Malte Kelm, Johannes Stegbauer, Miriam M. Cortese‐Krott   +7 more
wiley   +1 more source

Prognostic Biomarkers for Predicting Decompensation in Alcoholic and Nonalcoholic Patients With Compensated Cirrhosis: An Umbrella Review

Biochemistry Research International, Volume 2026, Issue 1, 2026.
Introduction Compensated cirrhosis carries a significant risk of progression to decompensation, which substantially worsens prognosis. Accurate prediction of decompensation events is critical for guiding surveillance, optimizing intervention timing, and improving patient outcomes.
Kristina Baktikulova, Saulesh Kurmangaliyeva, Amin Tamadon, Kairat Kurmangaliyev, Nadiar M. Mussin, Ramazon Safarzoda Sharoffidin, Jurandir Fernando Comar   +6 more
wiley   +1 more source

Stimulation of Erythrocyte Membrane Blebbing by Naproxen Sodium

Dose-Response, 2020
Naproxen sodium is a nonsteroidal anti-inflammatory drug (NSAID) having antipyretic and analgesic properties, mainly used for the treatment of rheumatoid arthritis and osteoarthritis.
Sajida Ilyas, Kashif Jilani, Muhammad Sikandar, Saba Siddiq, Muhammad Riaz, Ayesha Naveed, Ismat Bibi, Haq Nawaz, Muhammad Irfan, Asma Asghar   +9 more
doaj   +1 more source

Induction of Suicidal Erythrocyte Death by Novobiocin

Cellular Physiology and Biochemistry, 2014
Background: Novobiocin, an aminocoumarin antibiotic, interferes with heat shock protein 90 and hypoxia inducible factor dependent gene expression and thus compromises cell survival.
Adrian Lupescu, Rosi Bissinger, Tabea Herrmann, Gergely Oswald, Kashif Jilani, Florian Lang   +5 more
doaj   +1 more source

Toxic Evaluations of Calea phyllolepis Extracts Standardized on 6‐epi‐β‐Verbesinol Coumarate and Its In Silico Prediction of the Toxicity

Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.
In vivo and in silico toxicological effects of Calea phyllolepis extracts Standardized on 6‐epi‐β‐Verbesinol Coumarate. ABSTRACT Medicinal plants are traditionally used in folk medicine. Still, there is a misconception about the safety/efficacy of natural treatments, which results in few studies on the toxic, genotoxic, and mutagenic potential of ...
Suele Bierhals Vencato, Guilherme Borsoi, Cleverson Feistel, Mariele Feiffer Charão, Angélica Rocha Joaquim, Jaqueline Nascimento Picada, Alexandre de Barros Falcão Ferraz   +6 more
wiley   +1 more source