Results 61 to 70 of about 2,020 (175)

Red blood cell endothelial nitric oxide synthase: A major player in regulating cardiovascular health

British Journal of Pharmacology, Volume 183, Issue 1, Page 40-56, January 2026.
Abstract Red blood cells (RBCs) have traditionally been seen as simple carriers of gases and nutrients in the body. One important non‐canonical function of RBCs in the cardiovascular system is the regulation of nitric oxide (NO) metabolism. It has been shown that RBCs can scavenge NO, transport NO metabolites and produce NO in hypoxic conditions ...
Anthea LoBue, Sophia K. Heuser, Marla Lindemann, Junjie Li, Masudur Rahman, Malte Kelm, Johannes Stegbauer, Miriam M. Cortese‐Krott   +7 more
wiley   +1 more source

Vitamin C Inhibits Aggravated Eryptosis by Hydrogen Peroxide in Glucose-6-Phosphated Dehydrogenase Deficiency

Cellular Physiology and Biochemistry, 2016
Background/Aims: The study was aimed to investigate if vitamin C could exert protective effects on development of eryptosis caused by glucose-6-phosphate dehydrogenase (G6PD) deficiency and hydrogen peroxide. Methods: Isolated erythrocytes with different
Feng Shan, Rui Yang, Tiemei Ji, Fengjun Jiao   +3 more
doaj   +1 more source

Stimulation of Erythrocyte Membrane Blebbing by Naproxen Sodium

Dose-Response, 2020
Naproxen sodium is a nonsteroidal anti-inflammatory drug (NSAID) having antipyretic and analgesic properties, mainly used for the treatment of rheumatoid arthritis and osteoarthritis.
Sajida Ilyas, Kashif Jilani, Muhammad Sikandar, Saba Siddiq, Muhammad Riaz, Ayesha Naveed, Ismat Bibi, Haq Nawaz, Muhammad Irfan, Asma Asghar   +9 more
doaj   +1 more source

Prognostic Biomarkers for Predicting Decompensation in Alcoholic and Nonalcoholic Patients With Compensated Cirrhosis: An Umbrella Review

Biochemistry Research International, Volume 2026, Issue 1, 2026.
Introduction Compensated cirrhosis carries a significant risk of progression to decompensation, which substantially worsens prognosis. Accurate prediction of decompensation events is critical for guiding surveillance, optimizing intervention timing, and improving patient outcomes.
Kristina Baktikulova, Saulesh Kurmangaliyeva, Amin Tamadon, Kairat Kurmangaliyev, Nadiar M. Mussin, Ramazon Safarzoda Sharoffidin, Jurandir Fernando Comar   +6 more
wiley   +1 more source

Eryptosis

, 2019
Tato bakalářská práce popisuje zánik erytrocytů eryptózou, ale i jiné způsoby zániku červených krvinek. V úvodní části jsou stručně popsány obecné vlastnosti erytrocytů, stavba jejich buněčné membrány a vznik erytrocytů (= erytropoéza).
Nováková, Zuzana
core   +1 more source

Induction of Suicidal Erythrocyte Death by Novobiocin

Cellular Physiology and Biochemistry, 2014
Background: Novobiocin, an aminocoumarin antibiotic, interferes with heat shock protein 90 and hypoxia inducible factor dependent gene expression and thus compromises cell survival.
Adrian Lupescu, Rosi Bissinger, Tabea Herrmann, Gergely Oswald, Kashif Jilani, Florian Lang   +5 more
doaj   +1 more source

Oxidative Stress in Neonatal Disease: Established Organ Injury and Emerging Evidence for Skeletal Involvement

Oxidative Medicine and Cellular Longevity, Volume 2026, Issue 1, 2026.
Reactive oxygen and nitrogen species participate in physiological signaling and adaptation during fetal and neonatal development, whereas excessive, prolonged, or spatially dysregulated production may contribute to oxidative and nitrosative tissue injury.
Laura Cannavò, Virginia Beretta, Chiara Petrolini, Vincenzo Raitano, Elena Scarpa, Valentina Dell’Orto, Silvia Carloni, Maria Cristina Albertini, Serafina Perrone, Erika Ramos-Tovar   +9 more
wiley   +1 more source

Stimulation of Erythrocyte Cell Membrane Scrambling by Gedunin

Cellular Physiology and Biochemistry, 2014
Background/Aims: Gedunin, an inhibitor of heat shock protein HSP90, triggers apoptosis of tumor cells and is thus effective against malignancy. Moreover, the drug has antimalarial potency.
Adrian Lupescu, Rosi Bissinger, Jamshed Warsi, Kashif Jilani, Florian Lang   +4 more
doaj   +1 more source

Toxic Evaluations of Calea phyllolepis Extracts Standardized on 6‐epi‐β‐Verbesinol Coumarate and Its In Silico Prediction of the Toxicity

Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.
In vivo and in silico toxicological effects of Calea phyllolepis extracts Standardized on 6‐epi‐β‐Verbesinol Coumarate. ABSTRACT Medicinal plants are traditionally used in folk medicine. Still, there is a misconception about the safety/efficacy of natural treatments, which results in few studies on the toxic, genotoxic, and mutagenic potential of ...
Suele Bierhals Vencato, Guilherme Borsoi, Cleverson Feistel, Mariele Feiffer Charão, Angélica Rocha Joaquim, Jaqueline Nascimento Picada, Alexandre de Barros Falcão Ferraz   +6 more
wiley   +1 more source

Modulation of Autophagy by Ursolic and Betulinic Acids: Distinct Cytotoxic and Membrane‐Disruption in Malignant and Nonmalignant Cells

Cell Biology International, Volume 49, Issue 11, Page 1518-1536, November 2025.
ABSTRACT Autophagy is a critical adaptive mechanism in tumor cells that promotes survival under stress, but when dysregulated, it may trigger programmed cell death. The pentacyclic triterpenoids betulinic acid (BA) and ursolic acid (UA) are structurally related compounds that modulate autophagy; however, comparative insights into their effects on ...
Waleska Kerllen Martins, Tayana Mazin Tsubone, Chimara Emilia Nascimento Sanches, Cleidiane de Sousa Rocha, Ricardo Scarparo Navarro, Beatriz Simonsen Stolf, Susana Nogueira Diniz, Rosangela Itri, Mauricio S. Baptista   +8 more
wiley   +1 more source