Results 61 to 70 of about 1,947 (173)
Background/Aims: The study was aimed to investigate if vitamin C could exert protective effects on development of eryptosis caused by glucose-6-phosphate dehydrogenase (G6PD) deficiency and hydrogen peroxide. Methods: Isolated erythrocytes with different
Feng Shan +3 more
doaj +1 more source
Stimulation of Erythrocyte Membrane Blebbing by Naproxen Sodium
Naproxen sodium is a nonsteroidal anti-inflammatory drug (NSAID) having antipyretic and analgesic properties, mainly used for the treatment of rheumatoid arthritis and osteoarthritis.
Sajida Ilyas +9 more
doaj +1 more source
Introduction Compensated cirrhosis carries a significant risk of progression to decompensation, which substantially worsens prognosis. Accurate prediction of decompensation events is critical for guiding surveillance, optimizing intervention timing, and improving patient outcomes.
Kristina Baktikulova +6 more
wiley +1 more source
Induction of Suicidal Erythrocyte Death by Novobiocin
Background: Novobiocin, an aminocoumarin antibiotic, interferes with heat shock protein 90 and hypoxia inducible factor dependent gene expression and thus compromises cell survival.
Adrian Lupescu +5 more
doaj +1 more source
In vivo and in silico toxicological effects of Calea phyllolepis extracts Standardized on 6‐epi‐β‐Verbesinol Coumarate. ABSTRACT Medicinal plants are traditionally used in folk medicine. Still, there is a misconception about the safety/efficacy of natural treatments, which results in few studies on the toxic, genotoxic, and mutagenic potential of ...
Suele Bierhals Vencato +6 more
wiley +1 more source
Enhanced Eryptosis Following Auranofin Exposure
Background/Aims: The antiinflammatory, antimicrobial and anticancer drug auranofin has previously been shown to trigger apoptosis, the suicidal death of nucleated cells. Side effects of the drug include anaemia. At least in theory the anaemia could result from stimulation of suicidal death of erythrocytes or eryptosis, which involves cell shrinkage and
Kousi Alzoubi +3 more
openaire +3 more sources
Stimulation of Erythrocyte Cell Membrane Scrambling by Gedunin
Background/Aims: Gedunin, an inhibitor of heat shock protein HSP90, triggers apoptosis of tumor cells and is thus effective against malignancy. Moreover, the drug has antimalarial potency.
Adrian Lupescu +4 more
doaj +1 more source
ABSTRACT Autophagy is a critical adaptive mechanism in tumor cells that promotes survival under stress, but when dysregulated, it may trigger programmed cell death. The pentacyclic triterpenoids betulinic acid (BA) and ursolic acid (UA) are structurally related compounds that modulate autophagy; however, comparative insights into their effects on ...
Waleska Kerllen Martins +8 more
wiley +1 more source
Sulindac Sulfide Induced Stimulation of Eryptosis [PDF]
Sulindac sulfide, a non-steroidal anti-inflammatory drug (NSAID), stimulates apoptosis of tumor cells and is thus effective against malignancy. In analogy to apoptosis of nucleated cells, erythrocytes may undergo eryptosis, an apoptosis-like suicidal erythrocyte death, characterized by cell shrinkage and cell membrane scrambling with phosphatidylserine-
Zbidah, Mohanad +6 more
openaire +3 more sources
Eryptosis as an Underlying Mechanism in Systemic Lupus Erythematosus-Related Anemia
Background: The progression of systemic lupus erythematosus (SLE) leads to anemia in patients, adversely affecting prognosis. The diverse causes of anemia may include excessive eryptosis or premature suicidal erythrocyte death characterized by cell ...
Peipei Jiang +11 more
doaj +1 more source

