Results 41 to 50 of about 1,400 (161)
Erythrocyte Sodium Sensitivity and Eryptosis in Chronic Hemodialysis Patients
Kidney & Blood Pressure Research, 2017 Background/Aims: In hemodialysis (HD) patients the endothelial and erythrocyte glycocalyx is impaired which in turn correlates with elevated erythrocyte sodium sensitivity (ESS).
Anna Meyring-Wösten +8 more
doaj +1 more source
Enhanced Eryptosis Following Exposure to Dolutegravir [PDF]
Cellular Physiology and Biochemistry, 2016 Background/Aims: The viral integrase enzyme inhibitor dolutegravir is utilized for the treatment of immunodeficiency virus (HIV) infection. Knowledge on cytotoxicity of dolutegravir is limited. The present study thus explored, whether dolutegravir is able to trigger suicidal erythrocyte death or eryptosis, which is characterized by cell shrinkage and ...
A. A. M. Bhuyan +3 more
openaire +4 more sources
Eryptosis - the Neglected Cause of Anemia in End Stage Renal Disease
Kidney & Blood Pressure Research, 2017 End stage renal disease (ESRD) invariably leads to anemia which has been mainly attributed to compromised release of erythropoietin from the defective kidneys with subsequent impairment of erythropoiesis.
Florian Lang +3 more
doaj +1 more source
Spectosis: One small step for NLRP3 but a giant leap for human mature red blood cells. [PDF]
Clin Transl MedClinical and Translational Medicine, Volume 15, Issue 8, August 2025.
Chen Y, Zhang J, Hu X.
europepmc +2 more sources
Stimulation of Hemolysis and Eryptosis by β-Caryophyllene Oxide. [PDF]
Life (Basel), 2023 Background: Eryptosis stimulated by anticancer drugs can lead to anemia in patients. β-caryophyllene oxide (CPO) is an anticancer sesquiterpene present in various plants; however, its effect on the structure and function of human red blood cells (RBCs) remains unexplored.
Alghareeb SA, Alfhili MA, Alsughayyir J.
europepmc +4 more sources
Studying Mechanisms of Eryptosis [PDF]
Cytotechnology, 2005 Cellular stress leads to activation of erythrocyte cation channels with subsequent Ca2+ entry and stimulates a sphingomyelinase with subsequent formation of ceramide. Both signaling molecules then activate the death program of erythrocytes (eryptosis) which is characterized by phosphatidylserine exposure, cellular shrinkage, membrane blebbing and ...
Thomas Wieder +8 more
openaire +1 more source
Atorvastatin Induced Erythrocytes Membrane Blebbing
Dose-Response, 2019 Atorvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl-coenzymeA reductase, is usually used for the treatment of hypercholesterolemia. Besides its pharmacological and side actions, its toxic effects on human nucleus devoid of erythrocytes are still ...
Rumaisa Bashir Rana +7 more
doaj +1 more source
Enhanced Eryptosis Following Gramicidin Exposure [PDF]
Toxins, 2015 The peptide antibiotic and ionophore gramicidin has previously been shown to trigger apoptosis of nucleated cells. In analogy to apoptosis, the suicidal death of erythrocytes or eryptosis involves cell shrinkage and cell membrane scrambling with phosphatidylserine translocation to the erythrocyte surface. Triggers of eryptosis include oxidative stress,
Abaid Malik +4 more
openaire +3 more sources
Frontiers in Cell and Developmental Biology, 2020 Red blood cells (RBC) are the most abundant cells in the blood. Despite powerful defense systems against chemical and mechanical stressors, their life span is limited to about 120 days in healthy humans and further shortened in patients with kidney ...
Gabriela Ferreira Dias +9 more
doaj +1 more source
Enhanced Eryptosis Following Exposure to Lopinavir [PDF]
Cellular Physiology and Biochemistry, 2015 Background/Aims: The protease inhibitor lopinavir, used for the treatment of HIV infections, triggers suicidal death or apoptosis of nucleated cells. Side effects of lopinavir include anemia, which could in theory result from stimulation of suicidal erythrocyte death or eryptosis, characterized by cell shrinkage and by phospholipid scrambling of the ...
Rosi Bissinger +5 more
openaire +3 more sources