Results 41 to 50 of about 1,947 (173)
What should be responsible for eryptosis in chronic kidney disease?
Kidney & Blood Pressure Research, 2022 Background: Renal anemia is an important complication of chronic kidney disease (CKD). In addition to insufficient secretion of erythropoietin (EPO) and erythropoiesis disorders, the impact of eryptosis on renal anemia demands attention.
Dongxin Li +9 more
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Diverse Effect of Vitamin C and N-Acetylcysteine on Aluminum-Induced Eryptosis
Biochemistry Research International, 2021 Purpose. The role of oxidative stress in Aluminum (Al)-induced apoptotic effects has been investigated and suicidal death of erythrocytes, eryptosis, is characterized by cell shrinkage and phosphatidylserine externalization (PSE) at the surface of the ...
Ali Reza Zangeneh +4 more
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Enhanced Eryptosis Following Exposure to Dolutegravir [PDF]
Cellular Physiology and Biochemistry, 2016 Background/Aims: The viral integrase enzyme inhibitor dolutegravir is utilized for the treatment of immunodeficiency virus (HIV) infection. Knowledge on cytotoxicity of dolutegravir is limited. The present study thus explored, whether dolutegravir is able to trigger suicidal erythrocyte death or eryptosis, which is characterized by cell shrinkage and ...
A. A. M. Bhuyan +3 more
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Atorvastatin Induced Erythrocytes Membrane Blebbing
Dose-Response, 2019 Atorvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl-coenzymeA reductase, is usually used for the treatment of hypercholesterolemia. Besides its pharmacological and side actions, its toxic effects on human nucleus devoid of erythrocytes are still ...
Rumaisa Bashir Rana +7 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2020 Red blood cells (RBC) are the most abundant cells in the blood. Despite powerful defense systems against chemical and mechanical stressors, their life span is limited to about 120 days in healthy humans and further shortened in patients with kidney ...
Gabriela Ferreira Dias +9 more
doaj +1 more source
Eryptosis as a marker of Parkinson's disease
Aging, 2014 A major trend in recent Parkinson's disease (PD) research is the investigation of biological markers that could help in identifying at-risk individuals or to track disease progression and response to therapies. Central to this is the knowledge that inflammation is a known hallmark of PD and of many other degenerative diseases.
Pretorius, Etheresia +5 more
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The specific PKC-α inhibitor chelerythrine blunts costunolide-induced eryptosis [PDF]
, 2020 Costunolide, a natural sesquiterpene lactone, has multiple pharmacological activities such as neuroprotection or induction of apoptosis and eryptosis.
Rossi, Ranieri +13 more
core +2 more sources
Studying Mechanisms of Eryptosis [PDF]
Cytotechnology, 2005 Cellular stress leads to activation of erythrocyte cation channels with subsequent Ca2+ entry and stimulates a sphingomyelinase with subsequent formation of ceramide. Both signaling molecules then activate the death program of erythrocytes (eryptosis) which is characterized by phosphatidylserine exposure, cellular shrinkage, membrane blebbing and ...
Thomas Wieder +8 more
openaire +1 more source
Stimulation of Eryptosis by Anti-A IgG Antibodies [PDF]
Cellular Physiology and Biochemistry, 2007 Anti-A IgG antibodies have previously been shown to stimulate Ca(2+) entry into red blood cells. Increased cytosolic free Ca(2+) concentration is known to trigger eryptosis, i.e. suicidal erythrocyte death, characterized by exposure of phosphatidylserine at the erythrocyte surface.
Philipp, Attanasio +7 more
openaire +2 more sources
Storage of Erythrocytes Induces Suicidal Erythrocyte Death
Cellular Physiology and Biochemistry, 2016 Background/Aims: Similar to apoptosis of nucleated cells, red blood cells (RBC) can undergo suicidal cell death - called eryptosis. It is characterized by cell shrinkage and phosphatidylserine translocation.
Elisabeth Lang +11 more
doaj +1 more source