Results 31 to 40 of about 1,400 (161)

Stimulation of Eryptosis by Afatinib [PDF]

Cellular Physiology and Biochemistry, 2018
Background/Aims: The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor afatinib is primarily utilized for the treatment of non-small cell lung carcinoma. The drug is at least partially effective by triggering suicidal tumor cell death. Side effects of afatinib treatment include anemia.
Abdulla Al Mamun Bhuyan, Florian Lang
openaire   +3 more sources

Stimulation of Eryptosis by Narasin [PDF]

Cellular Physiology and Biochemistry, 2015
Background/Aims: Narasin, an ionophore used for the treatment of coccidiosis, has been shown to foster apoptosis of tumor cells. In analogy to apoptosis of nucleated cells, erythrocytes may enter eryptosis, the suicidal erythrocyte death characterized by cell shrinkage and cell membrane scrambling with phosphatidylserine translocation to the ...
Ghada Bouguerra, Rosi Bissinger, Salem Abbès, Florian Lang   +3 more
openaire   +3 more sources

Suicidal Erythrocyte Death in Metabolic Syndrome

Antioxidants, 2021
Eryptosis is a coordinated, programmed cell death culminating with the disposal of cells without disruption of the cell membrane and the release of endocellular oxidative and pro-inflammatory milieu.
Ignazio Restivo, Alessandro Attanzio, Luisa Tesoriere, Mario Allegra   +3 more
doaj   +1 more source

Testosterone inhibits eryptosis induced by hydrogen peroxide

Zhongguo shuxue zazhi, 2022
Objective To explore the mechanism of testosterone on eryptosis. Methods The erythrocyte suspension (1%) was cultured in vitro and divided into 3 groups: 2 kinds of eryptosis models induced by hydrogen peroxide (H2O2) in vitro, 3×10-8 mol/L testosterone +
Hua WEI, Na LI, Wenda FU, Shijie MU
doaj   +1 more source

Stimulation of Eryptosis by Cadmium Ions [PDF]

Cellular Physiology and Biochemistry, 2008
Cadmium ions are known to trigger apoptosis. Erythrocytes may similarly undergo suicidal death or eryptosis, which is characterized by exposure of phosphatidylserine at the erythrocyte surface. As macrophages are equipped with phosphatidylserine receptors, they bind, engulf and degrade phosphatidylserine exposing cells.
Mentor, Sopjani, Michael, Föller, Peter, Dreischer, Florian, Lang   +3 more
openaire   +2 more sources

Eryptosis, a Window to Systemic Disease [PDF]

Cellular Physiology and Biochemistry, 2008
Similar to apoptosis of nucleated cells, suicidal erythrocyte death or eryptosis is characterized by cell shrinkage, membrane blebbing and membrane phospholipid scrambling with phosphatidylserine exposure at the cell surface. Signaling of eryptosis involves formation of prostaglandin E(2) with subsequent activation of cation channels and Ca(2+)-entry ...
Florian, Lang, Erich, Gulbins, Holger, Lerche, Stephan M, Huber, Daniela S, Kempe, Michael, Foller   +5 more
openaire   +2 more sources

The impact of erythrocyte age on eryptosis [PDF]

British Journal of Haematology, 2012
SummaryMature, circulating erythrocytes undergo senescence, which limits their life span to approximately 120 d. Upon injury, erythrocytes may undergo suicidal erythrocyte death or eryptosis, which may accelerate senescence and shorten their survival.
Ghashghaeinia, M., Cluitmans, J.C.A., Akel, A., Dreischer, P., Toulany, M., Koberle, M., Skabytska, Y., Saki, M., Biedermann, T., Duszenko, M., Lang, F., Wieder, T., Bosman, G.J.C.G.M.   +12 more
openaire   +4 more sources

Methods Employed in Cytofluorometric Assessment of Eryptosis, the Suicidal Erythrocyte Death

Cellular Physiology and Biochemistry, 2017
Suicidal erythrocyte death or eryptosis contributes to or even accounts for anemia in a wide variety of clinical conditions, such as iron deficiency, dehydration, hyperphosphatemia, vitamin D excess, chronic kidney disease (CKD), hemolytic-uremic ...
Mohamed Jemaà, Myriam Fezai, Rosi Bissinger, Florian Lang   +3 more
doaj   +1 more source

What should be responsible for eryptosis in chronic kidney disease?

Kidney & Blood Pressure Research, 2022
Background: Renal anemia is an important complication of chronic kidney disease (CKD). In addition to insufficient secretion of erythropoietin (EPO) and erythropoiesis disorders, the impact of eryptosis on renal anemia demands attention.
Dongxin Li, Xujuan Zheng, Yunxia Zhang, Xiangling Li, Xuexun Chen, Yonghua Yin, Jingwen Hu, Jialin Li, Min Guo, Xiangming Wang   +9 more
doaj   +1 more source

Diverse Effect of Vitamin C and N-Acetylcysteine on Aluminum-Induced Eryptosis

Biochemistry Research International, 2021
Purpose. The role of oxidative stress in Aluminum (Al)-induced apoptotic effects has been investigated and suicidal death of erythrocytes, eryptosis, is characterized by cell shrinkage and phosphatidylserine externalization (PSE) at the surface of the ...
Ali Reza Zangeneh, Mohammad Ali Takhshid, Reza Ranjbaran, Mahsa Maleknia, Mohammad Hassan Meshkibaf   +4 more
doaj   +1 more source