Results 31 to 40 of about 2,020 (175)

Physiology and Pathophysiology of Eryptosis [PDF]

Transfusion Medicine and Hemotherapy, 2012
Suicidal erythrocyte death (eryptosis) is characterized by cell shrinkage, cell membrane blebbing, and cell membrane phospholipid scrambling with phosphatidylserine exposure at the cell surface. Eryptotic cells adhere to the vascular wall and are rapidly cleared from circulating blood. Eryptosis is stimulated by an increase in cytosolic Ca(2)+ activity,
Florian, Lang, Elisabeth, Lang, Michael, Föller   +2 more
openaire   +2 more sources

Association between vitamin D status and eryptosis–results from the German National Cohort Study [PDF]

, 2023
Vitamin D, besides its classical effect on mineral homeostasis and bone remodeling, can also modulate apoptosis. A special form of apoptosis termed eryptosis appears in erythrocytes.
Frank B. Kraus, Julia Kühn, Stangl, Gabriele I., Rafael Mikolajczyk, Föller, Michael, Ewendt, Franz, Ludwig-Kraus, Beatrice, Michael Föller, Schmitt, Marvin, Kraus, Frank B., Beatrice Ludwig-Kraus, Franz Ewendt, Bürkner, Paul-Christian, Kluttig, Alexander, Wim Wätjen, Frank Hirche, Alexander Kluttig, Hirche, Frank, Gabriele I. Stangl, Mikolajczyk, Rafael, Wätjen, Wim, Marvin Schmitt, Kühn, Julia, Paul-Christian Bürkner   +23 more
core   +3 more sources

Stimulation of Eryptosis by Caspofungin [PDF]

Cellular Physiology and Biochemistry, 2016
Background/Aims: The echinocandin antifungal agent caspofungin has been shown to trigger apoptosis of fungal cells. Beyond that, caspofungin is toxic for host mitochondria. Even though lacking mitochondria, erythrocytes may enter apoptosis-like suicidal erythrocyte death or eryptosis, characterized by cell shrinkage and cell membrane scrambling with ...
Thomas Peter, Rosi Bissinger, Florian Lang   +2 more
openaire   +3 more sources

Suicidal Erythrocyte Death in Metabolic Syndrome

Antioxidants, 2021
Eryptosis is a coordinated, programmed cell death culminating with the disposal of cells without disruption of the cell membrane and the release of endocellular oxidative and pro-inflammatory milieu.
Ignazio Restivo, Alessandro Attanzio, Luisa Tesoriere, Mario Allegra   +3 more
doaj   +1 more source

Testosterone inhibits eryptosis induced by hydrogen peroxide

Zhongguo shuxue zazhi, 2022
Objective To explore the mechanism of testosterone on eryptosis. Methods The erythrocyte suspension (1%) was cultured in vitro and divided into 3 groups: 2 kinds of eryptosis models induced by hydrogen peroxide (H2O2) in vitro, 3×10-8 mol/L testosterone +
Hua WEI, Na LI, Wenda FU, Shijie MU
doaj   +1 more source

Red blood cell membrane proteome as a reporter of disease severity, transfusion impact and genetic background in transfusion-dependent β-thalassaemia. [PDF]

Br J Haematol
Summary Omics technologies have transformed research in haemoglobinopathies, yet the proteome of RBCs remains largely unexplored in transfusion‐dependent thalassaemia (TDT). In this proteomic analysis, Red blood cell (RBC) membranes from 48 adults with TDT were compared with healthy controls.
Theocharaki K, Delicou S, Ntzoura-Kani A, Simantiris N, Politou M, Komninaka V, Samiotaki M, Zoidakis J, Antonelou MH.   +8 more
europepmc   +2 more sources

Stimulation of Eryptosis by Cadmium Ions [PDF]

Cellular Physiology and Biochemistry, 2008
Cadmium ions are known to trigger apoptosis. Erythrocytes may similarly undergo suicidal death or eryptosis, which is characterized by exposure of phosphatidylserine at the erythrocyte surface. As macrophages are equipped with phosphatidylserine receptors, they bind, engulf and degrade phosphatidylserine exposing cells.
Mentor, Sopjani, Michael, Föller, Peter, Dreischer, Florian, Lang   +3 more
openaire   +2 more sources

The specific PKC-α inhibitor chelerythrine blunts costunolide-induced eryptosis [PDF]

, 2020
Costunolide, a natural sesquiterpene lactone, has multiple pharmacological activities such as neuroprotection or induction of apoptosis and eryptosis.
Rossi, Ranieri, Ghashghaeinia, Mehrdad, Mrowietz, Ulrich, Giustarini, Daniela, Wieder, Thomas, Köberle, Martin, Lang, Florian, Mojzikova, Renata, Schaller, Martin, Dreischer, Peter, Koralkova, Pavla, Fehrenbacher, Birgit, Martínez-Ruiz, Antonio, Divoký, Vladimír   +13 more
core   +3 more sources

Eryptosis, a Window to Systemic Disease [PDF]

Cellular Physiology and Biochemistry, 2008
Similar to apoptosis of nucleated cells, suicidal erythrocyte death or eryptosis is characterized by cell shrinkage, membrane blebbing and membrane phospholipid scrambling with phosphatidylserine exposure at the cell surface. Signaling of eryptosis involves formation of prostaglandin E(2) with subsequent activation of cation channels and Ca(2+)-entry ...
Florian, Lang, Erich, Gulbins, Holger, Lerche, Stephan M, Huber, Daniela S, Kempe, Michael, Foller   +5 more
openaire   +2 more sources

Hemotrophic mycoplasmas induce programmed cell death in red blood cells [PDF]

, 2011
Hemotrophic mycoplasmas (HM) are uncultivable bacteria found on and in the red blood cells (RBCs). The main clinical sign of HM infections is the hemolytic anemia. However, anemia-inducing pathogenesis has not been totally clarified. In this work we used
Groebel, K, Ritzmann, Mathias, Hoelzle, Katharina, Kilchling, T, Mathias Ritzmann, Ritzmann, M, Felder, Kathrin M., Hoelzle, K, Ludwig E. Hoelzle, Schiele, D, Katharina Hoelzle, Heinritzi, K, Daniela Schiele, Kilchling, Tim, Kathrin M. Felder, Tim Kilchling, Karl Heinritzi, Felder, K M, Katrin Groebel, Heinritzi, Karl, Groebel, Katrin, Schiele, Daniela, Hoelzle, Ludwig E, Hoelzle, Ludwig E., Schiele D, Hoelzle LE, Heinritzi K, Kilchling T, Felder KM, Groebel K, Hoelzle K, Ritzmann M   +31 more
core   +1 more source