Results 31 to 40 of about 1,947 (173)
The Cytotoxic Effect of Septic Plasma on Healthy RBCs: Is Eryptosis a New Mechanism for Sepsis? [PDF]
Grazia Maria, Luca Sgarabotto
exaly +2 more sources
Physiology and Pathophysiology of Eryptosis [PDF]
Suicidal erythrocyte death (eryptosis) is characterized by cell shrinkage, cell membrane blebbing, and cell membrane phospholipid scrambling with phosphatidylserine exposure at the cell surface. Eryptotic cells adhere to the vascular wall and are rapidly cleared from circulating blood. Eryptosis is stimulated by an increase in cytosolic Ca(2)+ activity,
Florian, Lang +2 more
openaire +2 more sources
Red blood cell membrane proteome as a reporter of disease severity, transfusion impact and genetic background in transfusion-dependent β-thalassaemia. [PDF]
Summary Omics technologies have transformed research in haemoglobinopathies, yet the proteome of RBCs remains largely unexplored in transfusion‐dependent thalassaemia (TDT). In this proteomic analysis, Red blood cell (RBC) membranes from 48 adults with TDT were compared with healthy controls.
Theocharaki K +8 more
europepmc +2 more sources
Suicidal Erythrocyte Death in Metabolic Syndrome
Eryptosis is a coordinated, programmed cell death culminating with the disposal of cells without disruption of the cell membrane and the release of endocellular oxidative and pro-inflammatory milieu.
Ignazio Restivo +3 more
doaj +1 more source
Testosterone inhibits eryptosis induced by hydrogen peroxide
Objective To explore the mechanism of testosterone on eryptosis. Methods The erythrocyte suspension (1%) was cultured in vitro and divided into 3 groups: 2 kinds of eryptosis models induced by hydrogen peroxide (H2O2) in vitro, 3×10-8 mol/L testosterone +
Hua WEI, Na LI, Wenda FU, Shijie MU
doaj +1 more source
Association between vitamin D status and eryptosis–results from the German National Cohort Study [PDF]
Vitamin D, besides its classical effect on mineral homeostasis and bone remodeling, can also modulate apoptosis. A special form of apoptosis termed eryptosis appears in erythrocytes.
Frank B. Kraus +23 more
core +2 more sources
Chronic hemolysis, enhanced oxidative stress, and decreased nitric oxide (NO) bioavailability promote vasculopathy in sickle cell anemia (SCA). Oxidative stress and NO are known to modulate eryptosis in healthy red blood cells (RBCs); however, their role
Elie Nader +41 more
doaj +1 more source
Eryptosis, a Window to Systemic Disease [PDF]
Similar to apoptosis of nucleated cells, suicidal erythrocyte death or eryptosis is characterized by cell shrinkage, membrane blebbing and membrane phospholipid scrambling with phosphatidylserine exposure at the cell surface. Signaling of eryptosis involves formation of prostaglandin E(2) with subsequent activation of cation channels and Ca(2+)-entry ...
Florian, Lang +5 more
openaire +2 more sources
Stimulation of Eryptosis by Cadmium Ions [PDF]
Cadmium ions are known to trigger apoptosis. Erythrocytes may similarly undergo suicidal death or eryptosis, which is characterized by exposure of phosphatidylserine at the erythrocyte surface. As macrophages are equipped with phosphatidylserine receptors, they bind, engulf and degrade phosphatidylserine exposing cells.
Mentor, Sopjani +3 more
openaire +2 more sources
Hemotrophic mycoplasmas induce programmed cell death in red blood cells [PDF]
Hemotrophic mycoplasmas (HM) are uncultivable bacteria found on and in the red blood cells (RBCs). The main clinical sign of HM infections is the hemolytic anemia. However, anemia-inducing pathogenesis has not been totally clarified. In this work we used
Groebel, K +23 more
core +1 more source

