Results 21 to 30 of about 1,400 (161)

Current understanding of eryptosis: mechanisms, physiological functions, role in disease, pharmacological applications, and nomenclature recommendations. [PDF]

Cell Death Dis
Early studies have shown that erythrocytes have caspase-3 and caspase-8 and are capable of dying through an apoptotic-like cell death triggered by Ca2+ ionophores.
Tkachenko A, Alfhili MA, Alsughayyir J, Attanzio A, Al Mamun Bhuyan A, Bukowska B, Cilla A, Quintanar-Escorza MA, Föller M, Havranek O, Jilani K, Onishchenko A, Pretorius E, Prokopiuk V, Restivo I, Tesoriere L, Virzì GM, Wieder T.   +17 more
europepmc   +2 more sources

Association Between Nitric Oxide, Oxidative Stress, Eryptosis, Red Blood Cell Microparticles, and Vascular Function in Sickle Cell Anemia

Frontiers in Immunology, 2020
Chronic hemolysis, enhanced oxidative stress, and decreased nitric oxide (NO) bioavailability promote vasculopathy in sickle cell anemia (SCA). Oxidative stress and NO are known to modulate eryptosis in healthy red blood cells (RBCs); however, their role
Elie Nader, Marc Romana, Nicolas Guillot   +2 more
exaly   +3 more sources

Stimulation of Eryptosis by Cryptotanshinone [PDF]

Cellular Physiology and Biochemistry, 2014
Background/Aims: Cryptotanshinone, a component of Salvia miltiorrhiza Bunge roots, may trigger suicidal death or apoptosis of tumor cells and has thus been recommended for the prevention and treatment of malignancy.
Rosi Bissinger, Adrian Lupescu, Christine Zelenak, Kashif Jilani, Florian Lang   +4 more
doaj   +3 more sources

Smoking is associated with increased eryptosis, suicidal erythrocyte death, in a large population-based cohort. [PDF]

Sci Rep
Smoking has multiple detrimental effects on health, and is a major preventable cause of premature death and chronic disease. Despite the well-described effect of inhaled substances from tobacco smoke on cell toxicity, the association between smoking and ...
Schmitt M, Ewendt F, Kluttig A, Mikolajczyk R, Kraus FB, Wätjen W, Bürkner PC, Stangl GI, Föller M.   +8 more
europepmc   +2 more sources

Computerized Morphometric Analysis of Eryptosis [PDF]

Frontiers in Physiology, 2019
Eryptosis is the suicidal destruction-process of erythrocytes, much like apoptosis of nucleated cells, in the course of which the stressed red cell undergoes cell-shrinkage, vesiculation and externalization of membrane phosphatidylserine.
Sanu Susan Jacob, Keerthana Prasad, Pragna Rao, Asha Kamath, Roopa B Hegde, Roopa B Hegde, Prathap M Baby, Raghavendra K Rao   +7 more
doaj   +3 more sources

Red Blood Cell Glycation Triggers In Vivo Cerebral Erythrophagocytosis in Adult Zebrafish in a Model Mimicking Hemorrhagic Stroke. [PDF]

Compr Physiol
In zebrafish, glycated RBCs promoted increased erythrophagocytic activity in microglia/macrophages, revealing a potential mechanism linking diabetes‐induced RBC glycation to exacerbated inflammatory responses and secondary damage after ICH. ABSTRACT Hemorrhagic stroke, particularly intracerebral hemorrhage (ICH), is a highly lethal subtype of stroke ...
Morello E, Rondeau P, Canonne-Hergaux F, Bourdon E, Bringart M, Meilhac O, Couret D, Diotel N.   +7 more
europepmc   +2 more sources

The Cytotoxic Effect of Septic Plasma on Healthy RBCs: Is Eryptosis a New Mechanism for Sepsis? [PDF]

International Journal of Molecular Sciences, 2023
Matteo Marcello, Grazia Maria Virzì, Massimo de Cal   +2 more
exaly   +2 more sources

Physiology and Pathophysiology of Eryptosis [PDF]

Transfusion Medicine and Hemotherapy, 2012
Suicidal erythrocyte death (eryptosis) is characterized by cell shrinkage, cell membrane blebbing, and cell membrane phospholipid scrambling with phosphatidylserine exposure at the cell surface. Eryptotic cells adhere to the vascular wall and are rapidly cleared from circulating blood. Eryptosis is stimulated by an increase in cytosolic Ca(2)+ activity,
Florian, Lang, Elisabeth, Lang, Michael, Föller   +2 more
openaire   +2 more sources

Stimulation of Eryptosis by Caspofungin [PDF]

Cellular Physiology and Biochemistry, 2016
Background/Aims: The echinocandin antifungal agent caspofungin has been shown to trigger apoptosis of fungal cells. Beyond that, caspofungin is toxic for host mitochondria. Even though lacking mitochondria, erythrocytes may enter apoptosis-like suicidal erythrocyte death or eryptosis, characterized by cell shrinkage and cell membrane scrambling with ...
Thomas Peter, Rosi Bissinger, Florian Lang   +2 more
openaire   +3 more sources

Peritoneal Inflammation in PD-Related Peritonitis Induces Systemic Eryptosis: In Vitro and In Vivo Assessments [PDF]

International Journal of Molecular Sciences
Grazia Maria Virzì, Niccolo Morisi, Ilaria Tantillo   +2 more
exaly   +2 more sources