Results 21 to 30 of about 1,947 (173)

Enhanced Eryptosis Following Exposure to Lopinavir [PDF]

Cellular Physiology and Biochemistry, 2015
Background/Aims: The protease inhibitor lopinavir, used for the treatment of HIV infections, triggers suicidal death or apoptosis of nucleated cells. Side effects of lopinavir include anemia, which could in theory result from stimulation of suicidal erythrocyte death or eryptosis, characterized by cell shrinkage and by phospholipid scrambling of the ...
Rosi Bissinger, Sabrina Waibel, Ghada Bouguerra, Abdulla Al Mamun Bhuyan, Salem Abbès, Florian Lang   +5 more
openaire   +5 more sources

Eryptosis - the Neglected Cause of Anemia in End Stage Renal Disease

Kidney & Blood Pressure Research, 2017
End stage renal disease (ESRD) invariably leads to anemia which has been mainly attributed to compromised release of erythropoietin from the defective kidneys with subsequent impairment of erythropoiesis.
Florian Lang, Rosi Bissinger, Majed Abed, Ferruh Artunc   +3 more
doaj   +3 more sources

Eryptosis: An Erythrocyte’s Suicidal Type of Cell Death [PDF]

BioMed Research International, 2018
Erythrocytes play an important role in oxygen and carbon dioxide transport. Although erythrocytes possess no nucleus or mitochondria, they fulfil several metabolic activities namely, the Embden-Meyerhof pathway, as well as the hexose monophosphate shunt.
Lisa Repsold, Anna Margaretha Joubert
openaire   +5 more sources

Eryptosis: Programmed Death of Nucleus-Free, Iron-Filled Blood Cells

Cells, 2022
Human erythrocytes are organelle-free cells packaged with iron-containing hemoglobin, specializing in the transport of oxygen. With a total number of approximately 25 trillion cells per individual, the erythrocyte is the most abundant cell type not only ...
Peter Dreischer, Michael Duszenko, Jasmin Stein, Thomas Wieder   +3 more
doaj   +2 more sources

Smoking is associated with increased eryptosis, suicidal erythrocyte death, in a large population-based cohort [PDF]

Scientific Reports
Smoking has multiple detrimental effects on health, and is a major preventable cause of premature death and chronic disease. Despite the well-described effect of inhaled substances from tobacco smoke on cell toxicity, the association between smoking and ...
Marvin Schmitt, Franz Ewendt, Alexander Kluttig, Rafael Mikolajczyk, F. Bernhard Kraus, Wim Wätjen, Paul-Christian Bürkner, Gabriele I. Stangl, Michael Föller   +8 more
doaj   +2 more sources

Enhanced Eryptosis Following Exposure to Carnosic Acid [PDF]

Cellular Physiology and Biochemistry, 2015
Background/Aims: The phenolic abietane diterpene component of rosemary and sage, carnosic acid, may either induce or inhibit apoptosis of nucleated cells. The mechanisms involved in the effects of carnosic acid include altered mitochondrial function and gene expression.
Katja Stockinger, Rosi Bissinger, Ghada Bouguerra, Salem Abbès, Florian Lang   +4 more
openaire   +4 more sources

Computerized Morphometric Analysis of Eryptosis [PDF]

Frontiers in Physiology, 2019
Eryptosis is the suicidal destruction-process of erythrocytes, much like apoptosis of nucleated cells, in the course of which the stressed red cell undergoes cell-shrinkage, vesiculation and externalization of membrane phosphatidylserine.
Sanu Susan Jacob, Keerthana Prasad, Pragna Rao, Asha Kamath, Roopa B Hegde, Roopa B Hegde, Prathap M Baby, Raghavendra K Rao   +7 more
doaj   +3 more sources

Simvastatin, a Novel Stimulator of Eryptosis, the Suicidal Erythrocyte Death

Cellular Physiology and Biochemistry, 2017
Background/Aims: The 3-hydroxy-3-methyl-glutaryl-Coenzyme A (HMG-CoA) reductase inhibitor simvastatin has been shown to trigger apoptosis of several cell types. The substance has thus been proposed as an additional treatment of malignancy.
Abdulla Al Mamun Al Mamun Bhuyan, Sigrid Nüßle, Hang Cao, Shaqiu Zhang, Florian Lang   +4 more
doaj   +2 more sources

Triggering of Eryptosis, the Suicidal Erythrocyte Death, by Perifosine [PDF]

Cellular Physiology and Biochemistry, 2017
Background/Aims: The alkylphospholipid perifosine is used for the treatment of malignancy. The substance is effective by triggering suicidal tumor cell death or apoptosis. Side effects of perifosine include anemia. At least in theory, perifosine-induced anemia could result from stimulation of suicidal erythrocyte death or eryptosis.
Jasmin Egler, Florian Lang
openaire   +4 more sources

Red Blood Cell Glycation Triggers In Vivo Cerebral Erythrophagocytosis in Adult Zebrafish in a Model Mimicking Hemorrhagic Stroke. [PDF]

Compr Physiol
In zebrafish, glycated RBCs promoted increased erythrophagocytic activity in microglia/macrophages, revealing a potential mechanism linking diabetes‐induced RBC glycation to exacerbated inflammatory responses and secondary damage after ICH. ABSTRACT Hemorrhagic stroke, particularly intracerebral hemorrhage (ICH), is a highly lethal subtype of stroke ...
Morello E, Rondeau P, Canonne-Hergaux F, Bourdon E, Bringart M, Meilhac O, Couret D, Diotel N.   +7 more
europepmc   +2 more sources