Results 21 to 30 of about 2,020 (175)

Stimulation of Eryptosis by Afatinib [PDF]

Cellular Physiology and Biochemistry, 2018
Background/Aims: The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor afatinib is primarily utilized for the treatment of non-small cell lung carcinoma.
Abdulla Al Mamun Bhuyan, Florian Lang
core   +5 more sources

Enhanced Eryptosis Following Exposure to Lopinavir [PDF]

Cellular Physiology and Biochemistry, 2015
Background/Aims: The protease inhibitor lopinavir, used for the treatment of HIV infections, triggers suicidal death or apoptosis of nucleated cells.
Abdulla Al Mamun Bhuyan, Salem Abbès, Rosi Bissinger, Rosi Bissinger, Florian Lang, Ghada Bouguerra, Sabrina Waibel, Bhuyan, Abdulla Al Mamun, Lang, Florian, Bouguerra, Ghada, Abbes, Salem, Bissinger, Rosi, Waibel, Sabrina   +12 more
core   +5 more sources

Eryptosis: An Erythrocyte’s Suicidal Type of Cell Death [PDF]

BioMed Research International, 2018
Erythrocytes play an important role in oxygen and carbon dioxide transport. Although erythrocytes possess no nucleus or mitochondria, they fulfil several metabolic activities namely, the Embden-Meyerhof pathway, as well as the hexose monophosphate shunt.
Repsold, Lisa, Joubert, Annie M., Lisa Repsold, Anna Margaretha Joubert   +3 more
core   +5 more sources

Disrupting the Kinase–Phosphatase Equilibrium: A Unified Mechanism for Drug-Induced Eryptosis [PDF]

Hematology Reports
The advent of targeted cancer therapies has revolutionized oncology, yet the off-target effects of these agents on healthy cells remain a significant clinical challenge.
Mohamed Jemaà, Yesmine Lahlaoui, Ghofrane Kitar, Khouloud Khalfaoui, Imen Moumni, Ines Safra   +5 more
doaj   +2 more sources

Diverse Effect of Vitamin C and N-Acetylcysteine on Aluminum-Induced Eryptosis

Biochemistry Research International, 2021
Purpose. The role of oxidative stress in Aluminum (Al)-induced apoptotic effects has been investigated and suicidal death of erythrocytes, eryptosis, is characterized by cell shrinkage and phosphatidylserine externalization (PSE) at the surface of the ...
Ali Reza Zangeneh, Mohammad Ali Takhshid, Reza Ranjbaran, Mahsa Maleknia, Mohammad Hassan Meshkibaf   +4 more
doaj   +2 more sources

Eryptosis in polycythemia vera and essential thrombocythemia [PDF]

Postępy Higieny i Medycyny Doświadczalnej, 2020
Aim: Polycythemia vera (PV) and essential thrombocythemia (ET) are Philadelphia–negative myeloproliferative neoplasms with documented apoptosis impairment at the level of hematopoietic stem cell.
Chojnowski, Krzysztof, Treliński, Jacek, Sicińska, Paulina, Kopka, Paweł, Bliźniewska, Katarzyna, Duchnowicz, Piotr, Bukowska, Bożena   +6 more
core   +4 more sources

Enhanced Eryptosis Following Gramicidin Exposure [PDF]

Toxins, 2015
The peptide antibiotic and ionophore gramicidin has previously been shown to trigger apoptosis of nucleated cells. In analogy to apoptosis, the suicidal death of erythrocytes or eryptosis involves cell shrinkage and cell membrane scrambling with ...
Rosi Bissinger, Florian Lang, Guoxing Liu, Abaid Malik, Guilai Liu   +4 more
core   +4 more sources

Computerized Morphometric Analysis of Eryptosis [PDF]

Frontiers in Physiology, 2019
Eryptosis is the suicidal destruction-process of erythrocytes, much like apoptosis of nucleated cells, in the course of which the stressed red cell undergoes cell-shrinkage, vesiculation and externalization of membrane phosphatidylserine.
Sanu Susan Jacob, Keerthana Prasad, Pragna Rao, Asha Kamath, Roopa B Hegde, Roopa B Hegde, Prathap M Baby, Raghavendra K Rao   +7 more
doaj   +3 more sources

Eryptosis as an Underlying Mechanism in Systemic Lupus Erythematosus-Related Anemia

Cellular Physiology and Biochemistry, 2016
Background: The progression of systemic lupus erythematosus (SLE) leads to anemia in patients, adversely affecting prognosis. The diverse causes of anemia may include excessive eryptosis or premature suicidal erythrocyte death characterized by cell ...
Peipei Jiang, Maohong Bian, Wenjuan Ma, Chunqiu Liu, Peng Yang, Bangqiang Zhu, Yuanhong Xu, Meijuan Zheng, Jinpin Qiao, Zongwen Shuai, Xueyong Zhou, Dake Huang   +11 more
doaj   +2 more sources

Red Blood Cell Glycation Triggers In Vivo Cerebral Erythrophagocytosis in Adult Zebrafish in a Model Mimicking Hemorrhagic Stroke. [PDF]

Compr Physiol
In zebrafish, glycated RBCs promoted increased erythrophagocytic activity in microglia/macrophages, revealing a potential mechanism linking diabetes‐induced RBC glycation to exacerbated inflammatory responses and secondary damage after ICH. ABSTRACT Hemorrhagic stroke, particularly intracerebral hemorrhage (ICH), is a highly lethal subtype of stroke ...
Morello E, Rondeau P, Canonne-Hergaux F, Bourdon E, Bringart M, Meilhac O, Couret D, Diotel N.   +7 more
europepmc   +2 more sources