Results 51 to 60 of about 1,847 (171)

The Role of Eryptosis in the Pathogenesis of Renal Anemia: Insights From Basic Research and Mathematical Modeling

Frontiers in Cell and Developmental Biology, 2020
Red blood cells (RBC) are the most abundant cells in the blood. Despite powerful defense systems against chemical and mechanical stressors, their life span is limited to about 120 days in healthy humans and further shortened in patients with kidney ...
Gabriela Ferreira Dias, Gabriela Ferreira Dias, Nadja Grobe, Sabrina Rogg, David J. Jörg, Roberto Pecoits-Filho, Roberto Pecoits-Filho, Andréa Novais Moreno-Amaral, Peter Kotanko, Peter Kotanko   +9 more
doaj   +1 more source

Spectosis: One small step for NLRP3 but a giant leap for human mature red blood cells. [PDF]

Clin Transl Med
Clinical and Translational Medicine, Volume 15, Issue 8, August 2025.
Chen Y, Zhang J, Hu X.
europepmc   +2 more sources

Stimulation of Eryptosis by Anti-A IgG Antibodies [PDF]

Cellular Physiology and Biochemistry, 2007
Anti-A IgG antibodies have previously been shown to stimulate Ca(2+) entry into red blood cells. Increased cytosolic free Ca(2+) concentration is known to trigger eryptosis, i.e. suicidal erythrocyte death, characterized by exposure of phosphatidylserine at the erythrocyte surface.
Philipp, Attanasio, Ekaterina, Shumilina, Tobias, Hermle, Valentin, Kiedaisch, Philipp A, Lang, Stephan M, Huber, Thomas, Wieder, Florian, Lang   +7 more
openaire   +2 more sources

Induction of RBC eryptosis. [PDF]

, 2013
RBC (A, R1) were incubated at 37°C for 4 h at 2% hematocrit in presence (gray) or absence (black line) of ionomycin (1 µM) and, then, induction of eryptosis was verified by forward scatter measurement (B) and annexin V-PE staining (C).
Paulo Renato Rivas Totino (341334), Cláudio Tadeu Daniel-Ribeiro (341335), Maria de Fátima Ferreira-da-Cruz (5652754)   +2 more
core   +1 more source

Eryptosis as a marker of Parkinson's disease

Aging, 2014
A major trend in recent Parkinson's disease (PD) research is the investigation of biological markers that could help in identifying at-risk individuals or to track disease progression and response to therapies. Central to this is the knowledge that inflammation is a known hallmark of PD and of many other degenerative diseases.
Pretorius, Etheresia, Swanepoel, A.C. (Albe Carina), Buys, A.V. (Antonia Vergina), Vermeulen, Natasha, Duim, Wiebren, Kell, Douglas B.   +5 more
openaire   +2 more sources

Storage of Erythrocytes Induces Suicidal Erythrocyte Death

Cellular Physiology and Biochemistry, 2016
Background/Aims: Similar to apoptosis of nucleated cells, red blood cells (RBC) can undergo suicidal cell death - called eryptosis. It is characterized by cell shrinkage and phosphatidylserine translocation.
Elisabeth Lang, Vitaly I. Pozdeev, Haifeng C. Xu, Prashant V. Shinde, Kristina Behnke, Junnat M. Hamdam, Erik Lehnert, Rüdiger E. Scharf, Florian Lang, Dieter Häussinger, Karl S. Lang, Philipp A. Lang   +11 more
doaj   +1 more source

Erythrocyte ‘Feierzeit’ reaction: Novel filamentous and vesicular response to n‐butyl acetate

Journal of Microscopy, EarlyView.
Abstract Human erythrocytes (red blood cells; RBCs) undergo spontaneous disassembly after several hours of exposure to n‐butyl acetate (nBA). Images of the morphological changes were captured in time‐lapse sequences using differential interference contrast (DIC) light microscopy.
Philip W. Kuchel
wiley   +1 more source

Sulindac Sulfide – Induced Stimulation of Eryptosis [PDF]

Cellular Physiology and Biochemistry, 2012
Sulindac sulfide, a non-steroidal anti-inflammatory drug (NSAID), stimulates apoptosis of tumor cells and is thus effective against malignancy. In analogy to apoptosis of nucleated cells, erythrocytes may undergo eryptosis, an apoptosis-like suicidal erythrocyte death, characterized by cell shrinkage and cell membrane scrambling with phosphatidylserine-
Zbidah, Mohanad, Lupescu, Adrian, Yang, Wenting, Bosc, Anastasia, Jilani, Kashif, Shaik, Nazneen, Lang, Florian   +6 more
openaire   +3 more sources

Acute pain transfusion reaction in a patient with thalassemia: In‐depth characterization of short‐ and long‐term phenotypes

Transfusion, Volume 66, Issue 7, Page 1299-1315, July 2026.
Abstract Background Acute pain transfusion reaction (APTR) is a rare, under‐recognized condition of unknown etiology. It can cause significant distress in recipients, necessitating symptomatic management and, occasionally, hospitalization. Study Design and Methods Here, we present an APTR event in an adult subject with transfusion‐dependent thalassemia
Georgia Tzafa, Sophia Delicou, Ioanna Barla, Konstantina Theocharaki, Aggeliki Kondi, Athanassios D. Velentzas, Nikolaos Simantiris, Elli‐Anna Stylianaki, George Mpekoulis, Efthymia Pavlou, Niki Vassilaki, Ioannis V. Kostopoulos, Aikaterini Xydaki, Efrosyni Nomikou, Ioanna‐Katerina Aggeli, Nikolaos Thomaidis, Evangelos Gikas, Martina Samiotaki, Jerome Zoidakis, Constantina Politis, Marianna H. Antonelou   +20 more
wiley   +1 more source

Age Sensitivity of NFκB Abundance and Programmed Cell Death in Erythrocytes Induced by NFκB Inhibitors

Cellular Physiology and Biochemistry, 2013
Background/Aims: Erythrocytes may enter eryptosis, a suicidal death characterized by cell shrinkage and phosphatidylserine exposure at the erythrocyte outer membrane.
Mehrdad Ghashghaeinia, Judith C. Cluitmans, Mahmoud Toulany, Mohammad Saki, Martin Köberle, Elisabeth Lang, Peter Dreischer, Tilo Biedermann, Michael Duszenko, Florian Lang, Giel J. Bosman, Thomas Wieder   +11 more
doaj   +1 more source