Results 51 to 60 of about 1,400 (161)

Stimulation of Eryptosis by Anti-A IgG Antibodies [PDF]

Cellular Physiology and Biochemistry, 2007
Anti-A IgG antibodies have previously been shown to stimulate Ca(2+) entry into red blood cells. Increased cytosolic free Ca(2+) concentration is known to trigger eryptosis, i.e. suicidal erythrocyte death, characterized by exposure of phosphatidylserine at the erythrocyte surface.
Philipp, Attanasio, Ekaterina, Shumilina, Tobias, Hermle, Valentin, Kiedaisch, Philipp A, Lang, Stephan M, Huber, Thomas, Wieder, Florian, Lang   +7 more
openaire   +2 more sources

Age Sensitivity of NFκB Abundance and Programmed Cell Death in Erythrocytes Induced by NFκB Inhibitors

Cellular Physiology and Biochemistry, 2013
Background/Aims: Erythrocytes may enter eryptosis, a suicidal death characterized by cell shrinkage and phosphatidylserine exposure at the erythrocyte outer membrane.
Mehrdad Ghashghaeinia, Judith C. Cluitmans, Mahmoud Toulany, Mohammad Saki, Martin Köberle, Elisabeth Lang, Peter Dreischer, Tilo Biedermann, Michael Duszenko, Florian Lang, Giel J. Bosman, Thomas Wieder   +11 more
doaj   +1 more source

Eryptosis as a marker of Parkinson's disease

Aging, 2014
A major trend in recent Parkinson's disease (PD) research is the investigation of biological markers that could help in identifying at-risk individuals or to track disease progression and response to therapies. Central to this is the knowledge that inflammation is a known hallmark of PD and of many other degenerative diseases.
Pretorius, Etheresia, Swanepoel, A.C. (Albe Carina), Buys, A.V. (Antonia Vergina), Vermeulen, Natasha, Duim, Wiebren, Kell, Douglas B.   +5 more
openaire   +2 more sources

Erythrocyte ‘Feierzeit’ reaction: Novel filamentous and vesicular response to n‐butyl acetate

Journal of Microscopy, EarlyView.
Abstract Human erythrocytes (red blood cells; RBCs) undergo spontaneous disassembly after several hours of exposure to n‐butyl acetate (nBA). Images of the morphological changes were captured in time‐lapse sequences using differential interference contrast (DIC) light microscopy.
Philip W. Kuchel
wiley   +1 more source

Storage of Erythrocytes Induces Suicidal Erythrocyte Death

Cellular Physiology and Biochemistry, 2016
Background/Aims: Similar to apoptosis of nucleated cells, red blood cells (RBC) can undergo suicidal cell death - called eryptosis. It is characterized by cell shrinkage and phosphatidylserine translocation.
Elisabeth Lang, Vitaly I. Pozdeev, Haifeng C. Xu, Prashant V. Shinde, Kristina Behnke, Junnat M. Hamdam, Erik Lehnert, Rüdiger E. Scharf, Florian Lang, Dieter Häussinger, Karl S. Lang, Philipp A. Lang   +11 more
doaj   +1 more source

Acute pain transfusion reaction in a patient with thalassemia: In‐depth characterization of short‐ and long‐term phenotypes

Transfusion, EarlyView.
Abstract Background Acute pain transfusion reaction (APTR) is a rare, under‐recognized condition of unknown etiology. It can cause significant distress in recipients, necessitating symptomatic management and, occasionally, hospitalization. Study Design and Methods Here, we present an APTR event in an adult subject with transfusion‐dependent thalassemia
Georgia Tzafa, Sophia Delicou, Ioanna Barla, Konstantina Theocharaki, Aggeliki Kondi, Athanassios D. Velentzas, Nikolaos Simantiris, Elli‐Anna Stylianaki, George Mpekoulis, Efthymia Pavlou, Niki Vassilaki, Ioannis V. Kostopoulos, Aikaterini Xydaki, Efrosyni Nomikou, Ioanna‐Katerina Aggeli, Nikolaos Thomaidis, Evangelos Gikas, Martina Samiotaki, Jerome Zoidakis, Constantina Politis, Marianna H. Antonelou   +20 more
wiley   +1 more source

Sulindac Sulfide – Induced Stimulation of Eryptosis [PDF]

Cellular Physiology and Biochemistry, 2012
Sulindac sulfide, a non-steroidal anti-inflammatory drug (NSAID), stimulates apoptosis of tumor cells and is thus effective against malignancy. In analogy to apoptosis of nucleated cells, erythrocytes may undergo eryptosis, an apoptosis-like suicidal erythrocyte death, characterized by cell shrinkage and cell membrane scrambling with phosphatidylserine-
Zbidah, Mohanad, Lupescu, Adrian, Yang, Wenting, Bosc, Anastasia, Jilani, Kashif, Shaik, Nazneen, Lang, Florian   +6 more
openaire   +3 more sources

Estramustine-Induced Suicidal Erythrocyte Death

Cellular Physiology and Biochemistry, 2013
Background: The nitrogen mustard derivative of estradiol-17β-phosphate estramustine is used for the treatment of prostate cancer. Estramustine may trigger suicidal death of cancer cells. Side effects of estramustine include anemia.
Rosi Bissinger, Paola Modicano, Leonie Frauenfeld, Elisabeth Lang, Janin Jacobi, Caterina Faggio, Florian Lang   +6 more
doaj   +1 more source

Eryptosis: Programmed Death of Nucleus-Free, Iron-Filled Blood Cells

Cells, 2022
Human erythrocytes are organelle-free cells packaged with iron-containing hemoglobin, specializing in the transport of oxygen. With a total number of approximately 25 trillion cells per individual, the erythrocyte is the most abundant cell type not only ...
Peter Dreischer, Michael Duszenko, Jasmin Stein, Thomas Wieder   +3 more
doaj   +1 more source

Hypomorphic ATP11c is a novel regulator of decreased efficacy of transfused red blood cells in humans and mice

HemaSphere, Volume 10, Issue 1, January 2026.
Abstract Chronic red blood cell (RBC) transfusion sustains patients with diverse hematologic disorders, but repeated transfusion leads to iron overload and alloimmunization. Reducing transfusion burden requires identifying donor units that circulate more effectively after storage, yet determinants of this variability remain incompletely defined.
James C. Zimring, Ariel M. Hay, Monika Dzieciatkowska, Daniel Stephenson, Zachary B. Haiman, Steven Kleinman, Philip J. Norris, Michael P. Busch, Nareg Roubinian, Elisa Fermo, Paola Bianchi, Gregory R. Keele, Grier P. Page, Angelo D'Alessandro   +13 more
wiley   +1 more source