Results 71 to 80 of about 1,947 (173)

In Vitro Induction of Eryptosis by Uremic Toxins and Inflammation Mediators in Healthy Red Blood Cells

open access: yes, 2022
Eryptosis is the stress-induced RBC (red blood cell) death mechanism. It is known that eryptosis is largely influenced by plasma and blood composition, and that it is accelerated in patients affected by chronic kidney disease (CKD). The aim of this study
Battaglia, Giovanni Giorgio   +13 more
core   +1 more source

Patulin-Induced Suicidal Erythrocyte Death

open access: yesCellular Physiology and Biochemistry, 2013
Background: Patulin, the most common mycotoxin in apples and apple-derived products, triggers apoptosis and has thus been considered for the treatment of cancer. Similar to apoptosis of nucleated cells, erythrocytes may enter suicidal death or eryptosis,
Adrian Lupescu   +3 more
doaj   +1 more source

Induction of Erythrocyte Shrinkage by Omeprazole

open access: yesDose-Response, 2020
Omeprazole, a proton pump inhibitor blocks the H + /K + -ATPase channels of gastric parietal cells. It is used for the treatment of peptic ulcer. Prolonged use of omeprazole may involve in inducing anemia.
Ayesha Naveed   +11 more
doaj   +1 more source

Circulating Erythrocyte‐ and Endothelial‐Derived Microvesicles as Biomarkers of Hemolysis and Clinical Severity in Sickle Cell Disease

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 19, October 2025.
ABSTRACT Sickle cell disease (SCD) is a monogenic disorder caused by the presence of hemoglobin S (Hb S) and is associated with a wide range of clinical complications, including hemolytic anemia, vaso‐occlusive crises (VOC), and acute chest syndrome (ACS).
Khouloud Khalfaoui   +12 more
wiley   +1 more source

Induction of RBC eryptosis.

open access: yes, 2013
RBC (A, R1) were incubated at 37°C for 4 h at 2% hematocrit in presence (gray) or absence (black line) of ionomycin (1 µM) and, then, induction of eryptosis was verified by forward scatter measurement (B) and annexin V-PE staining (C).
Paulo Renato Rivas Totino (341334)   +2 more
core   +1 more source

Triggering of Suicidal Erythrocyte Death by Celecoxib

open access: yesToxins, 2013
The selective cyclooxygenase-2 (COX-2) inhibitor celecoxib triggers apoptosis of tumor cells and is thus effective against malignancy. The substance is at least partially effective through mitochondrial depolarization.
Florian Lang   +3 more
doaj   +1 more source

The Uremic Toxin Acrolein Promotes Suicidal Erythrocyte Death

open access: yesKidney & Blood Pressure Research, 2013
Background: Anemia is a major complication of end stage renal disease. The anemia is mainly the result of impaired formation of erythrocytes due to lack of erythropoietin and iron deficiency.
Mohamed Siyabeldin E. Ahmed   +4 more
doaj   +1 more source

Dapsone‐Induced Heinz Body Hemolytic Anemia: A Case Report

open access: yesClinical Case Reports, Volume 13, Issue 4, April 2025.
ABSTRACT Patients who develop acute anemia, without evidence of blood loss, should have a hemolysis workup including a medication review in case this could be contributing. In our patient's case, workup was significant for Heinz body hemolytic anemia due to home dapsone. Patient's anemia ultimately resolved with drug cessation.
Tyler Edwards   +2 more
wiley   +1 more source

Eryptosis in Patients with Chronic Kidney Disease: A Possible Relationship with Oxidative Stress and Inflammatory Markers

open access: yes, 2022
Background. Eryptosis is the programmed death of red blood cells; it may contribute to worsening anemia in chronic kidney disease (CKD). In this clinical condition, different factors induce eryptosis, such as oxidative stress, energy depletion and uremic
Grazia Virzì   +11 more
core   +1 more source

Sensitization of Erythrocytes to Suicidal Erythrocyte Death Following Water Deprivation

open access: yesKidney & Blood Pressure Research, 2013
Background/Aims: Klotho deficiency results in excessive formation of 1,25(OH)2D3, accelerated ageing and early death. Moreover, klotho deficiency enhances eryptosis, the suicidal erythrocyte death characterized by phosphatidylserine exposure at the ...
Majed Abed   +7 more
doaj   +1 more source

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