Results 71 to 80 of about 1,947 (173)
Eryptosis is the stress-induced RBC (red blood cell) death mechanism. It is known that eryptosis is largely influenced by plasma and blood composition, and that it is accelerated in patients affected by chronic kidney disease (CKD). The aim of this study
Battaglia, Giovanni Giorgio +13 more
core +1 more source
Patulin-Induced Suicidal Erythrocyte Death
Background: Patulin, the most common mycotoxin in apples and apple-derived products, triggers apoptosis and has thus been considered for the treatment of cancer. Similar to apoptosis of nucleated cells, erythrocytes may enter suicidal death or eryptosis,
Adrian Lupescu +3 more
doaj +1 more source
Induction of Erythrocyte Shrinkage by Omeprazole
Omeprazole, a proton pump inhibitor blocks the H + /K + -ATPase channels of gastric parietal cells. It is used for the treatment of peptic ulcer. Prolonged use of omeprazole may involve in inducing anemia.
Ayesha Naveed +11 more
doaj +1 more source
ABSTRACT Sickle cell disease (SCD) is a monogenic disorder caused by the presence of hemoglobin S (Hb S) and is associated with a wide range of clinical complications, including hemolytic anemia, vaso‐occlusive crises (VOC), and acute chest syndrome (ACS).
Khouloud Khalfaoui +12 more
wiley +1 more source
RBC (A, R1) were incubated at 37°C for 4 h at 2% hematocrit in presence (gray) or absence (black line) of ionomycin (1 µM) and, then, induction of eryptosis was verified by forward scatter measurement (B) and annexin V-PE staining (C).
Paulo Renato Rivas Totino (341334) +2 more
core +1 more source
Triggering of Suicidal Erythrocyte Death by Celecoxib
The selective cyclooxygenase-2 (COX-2) inhibitor celecoxib triggers apoptosis of tumor cells and is thus effective against malignancy. The substance is at least partially effective through mitochondrial depolarization.
Florian Lang +3 more
doaj +1 more source
The Uremic Toxin Acrolein Promotes Suicidal Erythrocyte Death
Background: Anemia is a major complication of end stage renal disease. The anemia is mainly the result of impaired formation of erythrocytes due to lack of erythropoietin and iron deficiency.
Mohamed Siyabeldin E. Ahmed +4 more
doaj +1 more source
Dapsone‐Induced Heinz Body Hemolytic Anemia: A Case Report
ABSTRACT Patients who develop acute anemia, without evidence of blood loss, should have a hemolysis workup including a medication review in case this could be contributing. In our patient's case, workup was significant for Heinz body hemolytic anemia due to home dapsone. Patient's anemia ultimately resolved with drug cessation.
Tyler Edwards +2 more
wiley +1 more source
Background. Eryptosis is the programmed death of red blood cells; it may contribute to worsening anemia in chronic kidney disease (CKD). In this clinical condition, different factors induce eryptosis, such as oxidative stress, energy depletion and uremic
Grazia Virzì +11 more
core +1 more source
Sensitization of Erythrocytes to Suicidal Erythrocyte Death Following Water Deprivation
Background/Aims: Klotho deficiency results in excessive formation of 1,25(OH)2D3, accelerated ageing and early death. Moreover, klotho deficiency enhances eryptosis, the suicidal erythrocyte death characterized by phosphatidylserine exposure at the ...
Majed Abed +7 more
doaj +1 more source

