Results 141 to 150 of about 14,499 (192)

The open architecture of HD-PTP phosphatase provides new insights into the mechanism of regulation of ESCRT function

Scientific Reports, 2017
HD-PTP is a tumour suppressor phosphatase that controls endocytosis, down-regulation of mitogenic receptors and cell migration. Central to its role is the specific recruitment of critical endosomal sorting complexes required for transport (ESCRTs ...
Deepankar Gahloth, Graham Heaven, Thomas A. Jowitt, A. Paul Mould, Jordi Bella, Clair Baldock, Philip Woodman, Lydia Tabernero   +7 more
doaj   +1 more source

Q&A: Cellular near death experiences-what is anastasis? [PDF]

, 2017
Apoptosis is a form of programmed cell death that is carried out by proteolytic enzymes called caspases. Executioner caspase activity causes cells to shrink, bleb, and disintegrate into apoptotic bodies and has been considered a point of no return for ...
Montell, Denise J, Sun, Gongping
core   +1 more source

Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology [PDF]

, 2015
Mutations in the charged multivesicular body protein 2B (CHMP2B) cause frontotemporal dementia (FTD). We report that mice which express FTD-causative mutant CHMP2B at physiological levels develop a novel lysosomal storage pathology characterised by large
Asante, EA, Clayton, EL, Collinge, J, Damirji, H, Edgar, JR, FReJA consortium, ., Holm, IE, Isaacs, AM, Johannsen, P, Marshall, S, Mizielinska, S, Nielsen, JE, Nielsen, TT, Norona, FE, Robbins, M   +14 more
core  

On the microstructure of active cellular processes [PDF]

, 2015
Eukaryotic cells use a multitude of protein machines to regulate their own structure. In this thesis, we study how the geometrical arrangement of these interacting microscopic active elements sculpt the cell's own internal microstructure and its membrane
Lenz, Martin
core   +2 more sources

Role And Regulation Of ESCRT-III In Multivesiculr Body Biogenesis [PDF]

, 2009
Endosomal sorting complex required for transports: ESCRT) machinery responsible for multivesicular body: MVB) biogenesis is essential for receptor downregulation, viral budding and cytokinesis.
Shim, Soomin
core   +1 more source

Molecular structure of the ESCRT-III-based archaeal CdvAB cell division machinery. [PDF]

Proc Natl Acad Sci U S A
Drobnič T, Salzer R, Nierhaus T, Jiang MKX, Bellini D, Steindorf A, Albers SV, Baum B, Löwe J.   +8 more
europepmc   +2 more sources

Membrane binding of a cyanobacterial ESCRT-III protein crucially involves the helix α1-3 hairpin conserved in all superfamily members. [PDF]

Protein Sci
Schlösser L, Kutzner M, Hellmann N, Kiesewetter D, Bieber J, Quarta N, Ge X, Goetze T, Junglas B, Matsumura F, Bonn M, Gräter F, Sachse C, Liu LN, Schmidt C, Aponte-Santamaría C, Schneider D.   +16 more
europepmc   +2 more sources

Roles of ESCRT-III polymers in cell division across the tree of life. [PDF]

Curr Opin Cell Biol, 2023
Carlton JG, Baum B.
europepmc   +1 more source

Correction to "Accessory ESCRT-III proteins are conserved and selective regulators of Rab11a-exosome formation". [PDF]

J Extracell Vesicles, 2023
Fan SJ.
europepmc   +1 more source

Vesicle-mediated transport of ALIX and ESCRT-III to the intercellular bridge during cytokinesis. [PDF]

Cell Mol Life Sci, 2023
Pust S, Brech A, Wegner CS, Stenmark H, Haglund K.   +4 more
europepmc   +1 more source