AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Clinical Characteristics, Molecular Diagnosis, and Drug Resistance Profiles of Nontuberculous Mycobacteria Infections: A Retrospective Analysis Using PCR Melting Curve Technology. [PDF]
ABSTRACT Nontuberculous mycobacteria (NTM) are emerging global pathogens. This study aimed to analyze the clinical features, species distribution, and drug resistance profiles of NTM infections in a northern Chinese hospital. A retrospective cohort study included 1769 patients with suspected mycobacterial infection from August 2023 to July 2025.
Wang K, Xu D, Gao Y, Zhao W, Ma K.
europepmc +2 more sources
Role of ethambutol and rifampicin in the treatment of Mycobacterium avium complex pulmonary disease
Background A three-drug regimen (macrolide, ethambutol, and rifampicin) is recommended for the treatment of Mycobacterium avium complex pulmonary disease (MAC-PD).
Hyung-Jun Kim +6 more
doaj +1 more source
Antimycobacterial Activities of an Edible Mushroom Extract and its Synergy with the Standard Antituberculous Drugs [PDF]
Introduction: Tuberculosis is a leading cause of death in most developing countries mainly due to drug resistance. Mushrooms are reservoirs of many unexplored active ingredients in relation to antimicrobial applications, giving us a scope to exploit it ...
Debasmita Chatterjee +4 more
doaj +1 more source
A truncated lipoglycan from mycobacteria with altered immunological properties [PDF]
Maintenance of cell-wall integrity in Mycobacterium tuberculosis is essential and is the target of several antitubercular drugs. For example, ethambutol targets arabinogalactan and lipoarabinomannan (LAM) biosynthesis through the inhibition of several ...
Alderwick, Luke J. +9 more
core +2 more sources
BackgroundThe purpose of this research was to investigate the characteristics, clinical manifestations, incidence, and risk factors in ethambutol-induced optic neuropathy (EON) in the Thai population.MethodsPatients treated with ethambutol for ...
Pareena Chaitanuwong +11 more
doaj +1 more source
On the analysis of tuberculosis studies with intermittent missing sputum data [PDF]
In randomized studies evaluating treatments for tuberculosis (TB), individuals are scheduled to be routinely evaluated for the presence of TB using sputum cultures. One important endpoint in such studies is the time of culture conversion, the first visit
Abraham, Maria +5 more
core +2 more sources
Breast tuberculosis in Northeast Iran: Review of 22 cases [PDF]
Background: Breast tuberculosis (breast TB) is an extremely rare disease, so case reviews are also rare.Methods: This study is a retrospective review of patients with breast TB who were treated between 2002 and 2012 at the Health Center of Gorgan City ...
Khodabakhshi, B., Mehravar, F.
core +2 more sources
Ethambutol optic neuropathy in the extended anti-tubercular therapy regime: A systematic review
The extended use of ethambutol beyond 2 months for treating tuberculosis has increased risk of optic neuropathy. We performed a systematic review of studies evaluating optic neuropathy in extended ethambutol use since 2010 and compared the outcome with a
Swapnali Sabhapandit +6 more
doaj +1 more source
embCAB Sequence Variation Among Ethambutol-Resistant Mycobacterium Tuberculosis Isolates Without embB306 Mutation [PDF]
Mechanisms of resistance to ethambutol in Mycobacterium tuberculosis remain inadequately described. Although there is mounting evidence that mutations of codon 306 in embB play a key role, a significant number of phenotypically ethambutol-resistant ...
Ahmad +27 more
core +2 more sources

