Results 11 to 20 of about 42,465 (246)

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Clinical Characteristics, Molecular Diagnosis, and Drug Resistance Profiles of Nontuberculous Mycobacteria Infections: A Retrospective Analysis Using PCR Melting Curve Technology. [PDF]

open access: yesClin Transl Sci
ABSTRACT Nontuberculous mycobacteria (NTM) are emerging global pathogens. This study aimed to analyze the clinical features, species distribution, and drug resistance profiles of NTM infections in a northern Chinese hospital. A retrospective cohort study included 1769 patients with suspected mycobacterial infection from August 2023 to July 2025.
Wang K, Xu D, Gao Y, Zhao W, Ma K.
europepmc   +2 more sources

Role of ethambutol and rifampicin in the treatment of Mycobacterium avium complex pulmonary disease

open access: yesBMC Pulmonary Medicine, 2019
Background A three-drug regimen (macrolide, ethambutol, and rifampicin) is recommended for the treatment of Mycobacterium avium complex pulmonary disease (MAC-PD).
Hyung-Jun Kim   +6 more
doaj   +1 more source

Antimycobacterial Activities of an Edible Mushroom Extract and its Synergy with the Standard Antituberculous Drugs [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2018
Introduction: Tuberculosis is a leading cause of death in most developing countries mainly due to drug resistance. Mushrooms are reservoirs of many unexplored active ingredients in relation to antimicrobial applications, giving us a scope to exploit it ...
Debasmita Chatterjee   +4 more
doaj   +1 more source

A truncated lipoglycan from mycobacteria with altered immunological properties [PDF]

open access: yes, 2010
Maintenance of cell-wall integrity in Mycobacterium tuberculosis is essential and is the target of several antitubercular drugs. For example, ethambutol targets arabinogalactan and lipoarabinomannan (LAM) biosynthesis through the inhibition of several ...
Alderwick, Luke J.   +9 more
core   +2 more sources

Incidence, risk factors and ophthalmic clinical characteristic of ethambutol-induced optic neuropathy: 7-year experience

open access: yesFrontiers in Ophthalmology, 2023
BackgroundThe purpose of this research was to investigate the characteristics, clinical manifestations, incidence, and risk factors in ethambutol-induced optic neuropathy (EON) in the Thai population.MethodsPatients treated with ethambutol for ...
Pareena Chaitanuwong   +11 more
doaj   +1 more source

On the analysis of tuberculosis studies with intermittent missing sputum data [PDF]

open access: yes, 2015
In randomized studies evaluating treatments for tuberculosis (TB), individuals are scheduled to be routinely evaluated for the presence of TB using sputum cultures. One important endpoint in such studies is the time of culture conversion, the first visit
Abraham, Maria   +5 more
core   +2 more sources

Breast tuberculosis in Northeast Iran: Review of 22 cases [PDF]

open access: yes, 2014
Background: Breast tuberculosis (breast TB) is an extremely rare disease, so case reviews are also rare.Methods: This study is a retrospective review of patients with breast TB who were treated between 2002 and 2012 at the Health Center of Gorgan City ...
Khodabakhshi, B., Mehravar, F.
core   +2 more sources

Ethambutol optic neuropathy in the extended anti-tubercular therapy regime: A systematic review

open access: yesIndian Journal of Ophthalmology, 2023
The extended use of ethambutol beyond 2 months for treating tuberculosis has increased risk of optic neuropathy. We performed a systematic review of studies evaluating optic neuropathy in extended ethambutol use since 2010 and compared the outcome with a
Swapnali Sabhapandit   +6 more
doaj   +1 more source

embCAB Sequence Variation Among Ethambutol-Resistant Mycobacterium Tuberculosis Isolates Without embB306 Mutation [PDF]

open access: yes, 2010
Mechanisms of resistance to ethambutol in Mycobacterium tuberculosis remain inadequately described. Although there is mounting evidence that mutations of codon 306 in embB play a key role, a significant number of phenotypically ethambutol-resistant ...
Ahmad   +27 more
core   +2 more sources

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