Results 91 to 100 of about 25,445 (232)
Introduction Pseudomonas aeruginosa is a leading cause of severe nosocomial infections worldwide. This opportunistic pathogen is associated with increased morbidity and mortality rates due to its high levels of antibiotic resistance. The identification of novel therapeutic targets is therefore a pressing global health priority.
Fatemeh Nasiri Khoonsari +2 more
wiley +1 more source
Into the cells of Escherichia coli (strain BL21(DE3)) two forms of the fusion protein Pseudomonas aeruginosa containing the full length outer membrane protein F (OprF) and nontoxic form of Exotoxin A (without 106 C-terminal amino acid residues) have been
A. V. Soldatenkova +4 more
doaj
Background and Objectives: Pseudomonas aeruginosa is a ubiquitous opportunistic pathogen. The presence of several virulence factors such as exotoxin and exoenzyme genes and biofilm may contribute to its pathogenicity.
Nima Bahador +6 more
doaj +1 more source
Crystal Structure of Exotoxin A from Aeromonas Pathogenic Species
Aeromonas exotoxin A (AE) is a bacterial virulence factor recently discovered in a clinical case of necrotising fasciitis caused by the flesh-eating Aeromonas hydrophila.
Geoffrey Masuyer
doaj +1 more source
Beta‐thalassemia is an inherited blood disorder associated with defective hemoglobin production and impaired immunity, increasing susceptibility to severe infections. Streptococcus pyogenes poses a significant risk due to its potential to cause streptococcal toxic shock syndrome (STSS), a life‐threatening condition characterized by fever, shock, and ...
Fajr Saeedi +2 more
wiley +1 more source
Group A β-Hemolytic Streptococcus Meningitis: Clinical and Microbiological Features of Nine Cases [PDF]
Group A β-hemolytic streptococcus (GAS) meningitis is a rare disease in adults. We conducted a retrospective study to describe clinical and microbiological features of nine cases of GAS meningitis in Switzerland.
Auckenthaler, Raymond +6 more
core
Elucidating the mechanisms of cooperative calcium-calmodulin interactions: a structural systems biology approach [PDF]
BACKGROUND: Calmodulin is an important multifunctional molecule that regulates the activities of a large number of proteins in the cell. Calcium binding induces conformational transitions in calmodulin that make it specifically active to particular ...
Bates, Declan +4 more
core +5 more sources
Nanobiosensor designing with molecular framework polymer method compared with agent-linked nanosilica biosensor for Staphylococcus aureus exotoxin detection [PDF]
Considering the ever increasing population and industrialization leading to developmental trend of humankind's life, we are hardly able to detect the toxins produced in food products using traditional techniques.
Ahari, H. +3 more
core
New and emerging therapeutic options for malignant pleural mesothelioma: review of early clinical trials. [PDF]
Malignant pleural mesothelioma (MPM) is a rare tumor that is challenging to control. Despite some benefit from using the multimodality-approach (surgery, combination chemotherapy and radiation), survival remains poor. However, current research produced a
Cameron, Robert B +2 more
core +2 more sources
Detection of Exotoxins and Antimicrobial Susceptibility Pattern in Clinical Pseudomonas Aeruginosa Isolates [PDF]
Background: Pseudomonas aeruginosa is a common opportunistic pathogen that causes nosocomial infection in immunocompromised patients. Among different virulence factors, the type III secretion system (TTSS) is an important agent in virulence and ...
Deris, Fatemeh. +4 more
core +1 more source

