Results 81 to 90 of about 25,445 (232)

Necrotizing Pneumonia Caused by PVL‐Negative Methicillin‐Susceptible Staphylococcus aureus Complicated by Refractory Pneumothorax: A Case Report

open access: yesRespirology Case Reports, Volume 14, Issue 1, January 2026.
Here we report a case of PVL‐negative MSSA necrotizing pneumonia in a previously healthy man that rapidly progressed to cavitary lesions and refractory pneumothorax. Despite its improvement after clindamycin‐based therapy, the patient experienced recurrent pneumothorax and chronic respiratory failure.
Shun Endo   +4 more
wiley   +1 more source

Effect of Pseudomonas aeruginosa Pure Exotoxin A on Mice WBC in Comparison with Human WBC Contaminated by Pseudomonas aeruginosa

open access: yesArmaghane Danesh Bimonthly Journal, 2008
Introduction & Objective: Pseudomonas aeruginosa is a gram negative bacterial. This bacterium is resistant to many antibiotics and chemical disinfectants.
M Naghmachi, A Sharifi, J Kohanteb
doaj  

Anthrax protective antigen is a calcium-dependent serine protease

open access: yesVirulence, 2018
Bacillus anthracis secretes a three component exotoxin-complex, which contributes to anthrax pathogenesis. Formation of this complex starts with the binding of protective antigen (PA) to its cellular receptor.
Lisanne Storm   +7 more
doaj   +1 more source

Considerations and challenges of septic arthritis and osteomyelitis

open access: yesEquine Veterinary Education, Volume 38, Issue 1, Page 19-25, January 2026.
Summary Septic arthritis remains a common orthopaedic condition in both human and veterinary medicine which can cause serious morbidity and pose considerable challenges for clinical management. The majority of the published clinical research in humans and veterinary species has been focused on the diagnosis, treatment, prevention and outcome of this ...
J. B. Engiles, H. L. Stewart
wiley   +1 more source

Identification of Distinct Bacillus thuringiensis 4A4 Nematicidal Factors Using the Model Nematodes Pristionchus pacificus and Caenorhabditis elegans

open access: yesToxins, 2014
Bacillus thuringiensis has been extensively used for the biological control of insect pests. Nematicidal B. thuringiensis strains have also been identified; however, virulence factors of such strains are poorly investigated.
Igor Iatsenko   +2 more
doaj   +1 more source

HER2-Specific Pseudomonas Exotoxin A PE25 Based Fusions: Influence of Targeting Domain on Target Binding, Toxicity, and In Vivo Biodistribution

open access: yesPharmaceutics, 2020
The human epidermal growth factor receptor 2 (HER2) is a clinically validated target for cancer therapy, and targeted therapies are often used in regimens for patients with a high HER2 expression level.
Haozhong Ding   +10 more
doaj   +1 more source

Progress of Programmed Cell Death in Steroid‐Induced Osteonecrosis of the Femoral Head

open access: yesOrthopaedic Surgery, Volume 18, Issue 1, Page 16-30, January 2026.
Steroid‐induced osteonecrosis of the femoral head is a severe osteoarticular condition resulting from glucocorticoid overuse, characterized by femoral head bone structure collapse and cell death, now predominant among nontraumatic femoral head necroses.
Zhi Kong, Chao Han
wiley   +1 more source

Determining Induction Conditions for Expression of Truncated Diphtheria Toxin and Pseudomonas Exotoxin A in E. coli BL21

open access: yesNovelty in Biomedicine, 2018
Background: Targeted cancer therapies have played a great role in the treatment of malignant tumors, in the recent years. Among these therapies, targeted toxin therapies such as immunotoxins, has improved the patient’s survival rate by minimizing the ...
Sahel Amoozadeh   +4 more
doaj   +1 more source

Mechanisms of Resistance to Immunotoxins Containing Pseudomonas Exotoxin A in Cancer Therapy

open access: yesBiomolecules, 2020
Immunotoxins are a class of targeted cancer therapeutics in which a toxin such as Pseudomonas exotoxin A (PE) is linked to an antibody or cytokine to direct the toxin to a target on cancer cells.
Michael Dieffenbach, Ira Pastan
doaj   +1 more source

How to rewire the host cell: A home improvement guide for intracellular bacteria. [PDF]

open access: yes, 2017
Intracellular bacterial pathogens have developed versatile strategies to generate niches inside the eukaryotic cells that allow them to survive and proliferate.
Cornejo, Elias   +2 more
core   +2 more sources

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