Results 111 to 120 of about 83,143 (262)
Brain and Behavior, Volume 16, Issue 2, February 2026.The gut microbiome in multiple sclerosis (MS) shows consistent depletion of short‐chain fatty acid (SCFA)‐producing bacteria, expansion of pro‐inflammatory species, and reduced levels of butyrate, propionate, and indole metabolites. These alterations increase intestinal permeability, disrupt immune balance, and contribute to blood–brain barrier ...
Husna Irfan Thalib +7 more
wiley +1 more source
Inhibition of the immunoproteasome ameliorates experimental autoimmune encephalomyelitis
EMBO Molecular Medicine, 2014 Multiple sclerosis (MS) is a chronic demyelinating immune mediated disease of the central nervous system. The immunoproteasome is a distinct class of proteasomes found predominantly in monocytes and lymphocytes. Recently, we demonstrated a novel function
Michael Basler +6 more
doaj +1 more source
Cell Biochemistry and Function, Volume 44, Issue 2, February 2026.ABSTRACT Living beings are persistently challenged by stress. Stress can be induced by internal stressors and external stressors. External stressors, including radiation, heat, heavy metals, nutritional imbalances, infections, and psychological stress, can induce protein denaturation, leading to misfolded or aggregated proteins.
Paka Sravan Kumar +5 more
wiley +1 more source
Role of nuclear factor κB in multiple sclerosis and experimental autoimmune encephalomyelitis
Neural Regeneration Research, 2018 The transcription factor nuclear factor κB (NF-κB) plays major roles in inflammatory diseases through regulation of inflammation and cell viability. Multiple sclerosis (MS) is a chronic inflammatory demyelinating and neurodegenerative disease of the ...
Yuan Yue, Sarrabeth Stone, Wensheng Lin
doaj +1 more source
The nod-like receptor, Nlrp12, plays an anti-inflammatory role in experimental autoimmune encephalomyelitis [PDF]
, 2015 Marjan Gharagozloo +8 more
openalex +1 more source
Isolation of Pure Stable Human Treg Cells Based on Expression of GPA33
European Journal of Immunology, Volume 56, Issue 2, February 2026.GPA33 identifies stable human regulatory T cells suitable for therapeutic use. GPA33+ Treg subsets expand efficiently, maintain high FOXP3+Helios+ expression, and lack production of IL‐2, IFNγ, and IL‐17A. GPA33, alone or combined with TIGIT, also enables robust post‐expansion isolation of pure, stable Treg cells for adoptive cell therapy.
Florencia Morgana +2 more
wiley +1 more source
European Journal of Immunology, Volume 56, Issue 2, February 2026.Mechanism of action of the intestinal microbiota on CNS autoimmune diseases. Environmental factors shape gut microbiota composition; dysbiosis alters microbial metabolites and antigenic signals. These modulate innate and adaptive immunity, affect barrier integrity, and influence CNS‐resident cells such as microglia and astrocytes, contributing to ...
Matteo Ceccon, Francesca Ronchi
wiley +1 more source
Neural Regeneration Research, 2016 Hydroxycitric acid (HCA) is derived primarily from the Garcinia plant and is widely used for its anti-inflammatory effects. Multiple sclerosis can cause an inflammatory demyelination and axonal damage.
Mahdi Goudarzvand +11 more
doaj +1 more source
Advances in the Role of Adipose Tissue in Promoting Injury Repair and Resist Infection
Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.ABSTRACT Background In recent years, adipose tissue (AT) transplantation has increasingly been noticed by many people in the field of tissue repair and regeneration. Accumulating evidence demonstrates that AT exerts dual functions in promoting tissue repair and conferring anti‐infective properties, with distinct biological effects attributed to its ...
Xi Duan +4 more
wiley +1 more source
Innate immunomodulation with MIS416: mechanism of action in experimental autoimmune encephalomyelitis [PDF]
, 2015 Madeleine P. J. White
openalex +1 more source