Results 31 to 40 of about 81,192 (267)

Oxidative Signaling in Experimental Autoimmune Encephalomyelitis [PDF]

Toxicological Sciences, 2010
The article by Johnson et al. on the role of antioxidant signaling pathways in a model of experimental autoimmune encephalomyelitis (EAE) merits further discussion. This group hypothesized that alterations in oxidative signaling may be involved in the development of EAE and multiple sclerosis (MS).
Gary W. Miller, Alison I. Bernstein
openaire   +3 more sources

Tim-3 Relieves Experimental Autoimmune Encephalomyelitis by Suppressing MHC-II

Frontiers in Immunology, 2022
Tim-3, an immune checkpoint inhibitor, is widely expressed on the immune cells and contributes to immune tolerance. However, the mechanisms by which Tim-3 induces immune tolerance remain to be determined.
Lili Tang, Ge Li, Yang Zheng, Chunmei Hou, Yang Gao, Ying Hao, Zhenfang Gao, Rongliang Mo, Yuxiang Li, Beifen Shen, Renxi Wang, Zhiding Wang, Zhiding Wang, Gencheng Han   +13 more
doaj   +1 more source

The Innate Immune Receptor CD14 Mediates Lymphocyte Migration in EAE

Cellular Physiology and Biochemistry, 2015
Background: Multiple sclerosis is the most common autoimmune disease of the central nervous system in young adults and histopathologically characterized by inflammation, demyelination and gliosis.
Ramona Halmer, Laura Davies, Yang Liu, Klaus Fassbender, Silke Walter   +4 more
doaj   +1 more source

Gestational hypothyroxinemia affects its offspring with a reduced suppressive capacity impairing the outcome of the experimental autoimmune encephalomyelitis [PDF]

, 2018
Indexación: Scopus.Hypothyroxinemia (Hpx) is a thyroid hormone deficiency (THD) condition highly frequent during pregnancy, which although asymptomatic for the mother, it can impair the cognitive function of the offspring.
Albornoz, E., Binzberger, R., Bueno, S.M., Bugueño, K., Cabello-Verrugio, C., Elorza, A.A., Haensgen, H., Jara Fernández, E.L., Kalergis, A.M., Opazo, M.C., Riedel, C.A., Rivero-Castillo, T., Simon, F., Venegas Salas, L.F.   +13 more
core   +2 more sources

ADAMTS13 ameliorates inflammatory responses in experimental autoimmune encephalomyelitis

Journal of Neuroinflammation, 2020
Background ADAMTS13 (a disintegrin and metalloprotease with a thrombospondin type 1 motif, member 13) plays a vital role in preventing microvascular thrombosis and inflammation.
Kaili Lu, Lan Liu, Xiaofeng Xu, Fei Zhao, Jiangshan Deng, Xin Tang, Xiuzhe Wang, Bing-Qiao Zhao, Xiaojie Zhang, Yuwu Zhao   +9 more
doaj   +1 more source

Characterization of immune response to neurofilament light in experimental autoimmune encephalomyelitis [PDF]

, 2013
PMCID: PMC3856490This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided ...
Amor, S, Baker, D, Beyer, C, Gerritsen, W, Huizinga, R, Kipp, M, Peferoen-Baert, R, Pryce, G, Puentes, F, Reijerkerk, A, Ummenthum, K, van der Star, BJ, van der Valk, P, Victor, M   +13 more
core   +5 more sources

A Role for the Intestinal Microbiota and Virome in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)? [PDF]

, 2016
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a heterogeneous disorder of significant societal impact that is proposed to involve both host and environmentally derived aetiologies that may be autoimmune in nature. Immune-related symptoms
Acheson, Bassi, Burbelo, Caligiuri, Carlo-Stella, Collins, Enbom, Fattah, Fremont, Gill, Jason, Klein, Klimas, Kumar, Lerner, Lerner, Maes, Meeus, Nishikai, Sharpe, Sheedy, Tannock, Vollmer-Conna   +22 more
core   +2 more sources

Experimental Autoimmune Encephalomyelitis [PDF]

, 2012
Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis (MS). MS is also named encephalomyelitis disseminata (ED). EAE has been also called experimental allergic encephalomyelitis, but the word `allergic` is more and more replaced by the word `autoimmune`.
openaire   +3 more sources

Induction of inhibitory central nervous system-derived and stimulatory blood-derived dendritic cells suggests a dual role for granulocyte-macrophage colony-stimulating factor in central nervous system inflammation [PDF]

, 2017
The mononuclear phagocyte system, particularly dendritic cells, plays several pivotal roles in the development of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis.
Fontana, Adriano, Heikenwalder, Mathias, Hesske, Lysann, Prinz, Marco, Reith, Walter, Suter, Tobias, Vincenzetti, Christine   +6 more
core  

Durable B‐Cell Impairment While Sparing IgA B Cells After Ocrelizumab Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Ocrelizumab (OCR), a humanized anti‐CD20 monoclonal antibody, is highly efficient in relapsing–remitting multiple sclerosis (RR‐MS). We assessed early cellular B‐cell profiles in patients prior to OCR treatment, on OCR treatment, and after 15 months of therapy discontinuation.
Alexandra Garcia, Stephane Rodriguez, Emilie Dugast, Christine Lebrun‐Frenay, Eric Thouvenot, Jérôme de Sèze, Emmanuelle Le Page, Sandra Vukusic, Inès Doghri, Eric Berger, Olivier Casez, Pierre Labauge, Aurélie Ruet, Catarina Raposo, Fabienne Le Frère, Arnaud B. Nicot, Sandrine Wiertlewski, Pierre‐Antoine Gourraud, Laure Michel, Laureline Berthelot, David‐Axel Laplaud   +20 more
wiley   +1 more source