Results 111 to 120 of about 27,541,156 (167)

Exportin 1 Inhibitor Combined With Venetoclax Induces Apoptosis in Myelodysplastic Syndrome by Mitochondria‐Induced Apoptosis Pathway

Journal of clinical laboratory analysis (Print)
Myelodysplastic syndromes (MDS) are clonal hematopoietic malignancies that pose a serious health threat. Current therapies include symptomatic treatments for low‐risk and hypomethylating agents for high‐risk MDS. However, many patients develop resistance
Xiaohan Liu, Lei Huang, Junzhu Wang, Yixuan Guo, Hongli Shen, X. Zhao, L. Yue, Zhaoyun Liu, Rong Fu   +8 more
semanticscholar   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio
BMI‐1 (B‐cell‐specific Moloney murine leukemia virus integration site 1) has been implicated in both normal and cancer cell biology. While the canonical function of BMI‐1 involves epigenetic repression, novel extranuclear functions have been recently ...
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
doaj   +1 more source

22P Exploring exportin-1 as a therapeutic vulnerability in lung squamous cell carcinoma

ESMO Open, 2023
V. Durani, R. Caeser, Á. Quintanal-Villalonga, C. Rudin   +3 more
semanticscholar   +1 more source

Melphalan and Exportin 1 Inhibitors Exert Synergistic Antitumor Effects in Preclinical Models of Human Multiple Myeloma. [PDF]

Cancer Res, 2020
Turner JG, Cui Y, Bauer AA, Dawson JL, Gomez JA, Kim J, Cubitt CL, Nishihori T, Dalton WS, Sullivan DM.   +9 more
europepmc   +1 more source

A new therapeutic approach to <i>KRAS</i> mutant non-small cell lung cancer: the emerging role of exportin 1 inhibition. [PDF]

Transl Lung Cancer Res
von Itzstein MS, Gerber DE.
europepmc   +1 more source

Exportin 1 (XPO1; CRM1); histone deacetylase 1 (HDAC1) [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Exportin 1 Inhibition Induces Nerve Growth Factor Receptor Expression to Inhibit the NF-κB Pathway in Preclinical Models of Pediatric High-Grade Glioma. [PDF]

Mol Cancer Ther, 2020
DeSisto JA, Flannery P, Lemma R, Pathak A, Mestnik S, Philips N, Bales NJ, Kashyap T, Moroze E, Venkataraman S, Kung AL, Carter BD, Landesman Y, Vibhakar R, Green AL.   +14 more
europepmc   +1 more source

Unbiased screening reveals that blocking exportin 1 overcomes resistance to PI3Kα inhibition in breast cancer. [PDF]

Signal Transduct Target Ther, 2019
Liu XL, Wang BB, Wang Y, Wang YX, Yang CH, Tan C, Zhang X, He QJ, Ding J, Meng LH.   +9 more
europepmc   +1 more source

Phase I/II Trial of Exportin 1 Inhibitor Selinexor plus Docetaxel in Previously Treated, Advanced KRAS-Mutant Non-Small Cell Lung Cancer. [PDF]

Clin Cancer Res
von Itzstein MS, Burns TF, Dowell JE, Horn L, Camidge DR, York SJ, Eaton KD, Kyle K, Fattah F, Liu J, Mu-Mosley H, Gupta A, Nadeem U, Gao A, Zhang S, Gerber DE.   +15 more
europepmc   +1 more source

Correction: Targeting mantle cell lymphoma metabolism and survival through simultaneous blockade of mTOR and nuclear transporter exportin-1. [PDF]

Oncotarget, 2019
Sekihara K, Saitoh K, Han L, Ciurea S, Yamamoto S, Kikkawa M, Kazuno S, Taka H, Kaga N, Arai H, Miida T, Andreeff M, Konopleva M, Tabe Y.   +13 more
europepmc   +1 more source