Results 41 to 50 of about 9,726 (170)
FAAH-Catalyzed C-C Bond Cleavage of a New Multitarget Analgesic Drug.
, 2018 The discovery of extended catalytic versatilities is of great importance in both the chemistry and biotechnology fields. Fatty acid amide hydrolase (FAAH) belongs to the amidase signature superfamily and is a major endocannabinoid inactivating enzyme ...
Jose L. Martos (5818553) +67 more
core +1 more source
Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders
Clinical, Cosmetic and Investigational Dermatology, 2020 Sudhir M Baswan,1,* Allison E Klosner,2,* Kelly Glynn,1 Arun Rajgopal,1 Kausar Malik,1 Sunghan Yim,1 Nathan Stern1 1Innovation and Science, Amway Corporation, Ada, MI, 49355, USA; 2Innovation and Science, Nutrilite Health Institute, Amway Corporation ...
Baswan SM +6 more
doaj
Plant Direct, 2022 Fatty acid amide hydrolase (FAAH) is a conserved amidase that is known to modulate the levels of endogenous N‐acylethanolamines (NAEs) in both plants and animals.
Omar Arias‐Gaguancela +3 more
doaj +1 more source
Membrane lipids are key modulators of the endocannabinoid-hydrolase FAAH
, 2014 Lipid composition is expected to play an important role in modulating membrane enzyme activity, in particular if the substrates are themselves lipid molecules.
Del Carlo M +10 more
core +2 more sources
Phytotherapy Research, EarlyView.Functional dyspepsia involves duodenal barrier dysfunction, low‐grade immune activation and altered neuroimmune signalling. Various plant‐derived bioactives may modulate PPAR signalling, reduce inflammatory and oxidative stress, and support epithelial, immune, metabolic, and sensory homeostasis.
Irene Palenca +5 more
wiley +1 more source
Investigating Endocannabinoid Metabolism in Alcohol Use Disorder: a focus on fatty acid amide hydrolase (FAAH) [PDF]
, 2022 The endocannabinoid enzyme, fatty acid amide hydrolase (FAAH), has been proposed as a therapeutic target for Alcohol Use Disorder (AUD) and psychiatric illnesses. Studies suggest that FAAH regulates alcohol intake/preference, and its impairment increases
Best, Laura M
core +1 more source
Türk Biyokimya DergisiObesity is a global health problem related to reduced life quality and shorter life expectancy. Given the fact that genetic factors play a role in obesity development, studies have suggested that polymorphisms of cannabinoid receptor 1 (CNR1 ...
Altun Beril +8 more
doaj +1 more source
A pro-nociceptive phenotype unmasked in mice lacking fatty-acid amide hydrolase
Molecular Pain, 2016 Fatty-acid amide hydrolase (FAAH) is the major enzyme responsible for degradation of anandamide, an endocannabinoid. Pharmacological inhibition or genetic deletion of FAAH (FAAH KO) produces antinociception in preclinical pain models that is largely ...
Lawrence M Carey BA, MS +6 more
doaj +1 more source
Crystals, 2019 Fatty acid amide hydrolase (FAAH) is a well-characterized member of the amidase signature (AS) family of serine hydrolases. The membrane-bound FAAH protein is responsible for the catabolism of neuromodulatory fatty acid amides, including anandamide and ...
Cho-Ah Min +6 more
doaj +1 more source
Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?
British Journal of Pharmacology, EarlyView.Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli +7 more
wiley +1 more source