Results 81 to 90 of about 2,205,533 (300)

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

Regulation of regulators: Role of the complement factor H-related proteins

Seminars in Immunology, 2019
The complement system, while being an essential and very efficient effector component of innate immunity, may cause damage to the host and result in various inflammatory, autoimmune and infectious diseases or cancer, when it is improperly activated or regulated.
Cserhalmi, Marcell, Papp, A., Brandus, B., Uzonyi, Barbara, Józsi, Mihály   +4 more
openaire   +4 more sources

Functional analysis and binding affinity of tomato ethylene response factors provide insight on the molecular bases of plant differential responses to ethylene [PDF]

, 2012
Background : The phytohormone ethylene is involved in a wide range of developmental processes and in mediating plant responses to biotic and abiotic stresses.
Bouzayen, Mondher, Chen, Kunsong, Latché, Alain, Mila, Isabelle, Ohme-Takagi, Masaru, Pech, Jean-Claude, Pirrello, Julien, Prasad, Narasimha, Regad, Farid, Zhang, Wangshu, Zouine, Mohamed   +10 more
core   +5 more sources

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Recurrence of Complement Factor H-Related Protein 5 Nephropathy in a Renal Transplant [PDF]

American Journal of Transplantation, 2011
Complement factor H-related protein 5 (CFHR5) nephropathy is a familial renal disease endemic in Cyprus. It is characterized by persistent microscopic hematuria, synpharyngitic macroscopic hematuria and progressive renal impairment. Isolated glomerular accumulation of complement component 3 (C3) is typical with variable degrees of glomerular ...
Vernon, KA, Gale, DP, de Jorge, E Goicoechea, McLean, AG, Galliford, J, Pierides, A, Maxwell, PH, Taube, D, Pickering, MC, Cook, HT   +9 more
openaire   +2 more sources

Association of Complement-Related Proteins in Subjects With and Without Second Trimester Gestational Diabetes

Frontiers in Endocrinology, 2021
IntroductionGestational Diabetes Mellitus (GDM) development is related to underlying metabolic syndrome that is associated with elevated complement C3 and C4.
Manjunath Ramanjaneya, Manjunath Ramanjaneya, Alexandra E. Butler, Meis Alkasem, Mohammed Bashir, Jayakumar Jerobin, Jayakumar Jerobin, Angela Godwin, Abu Saleh Md Moin, Lina Ahmed, Mohamed A. Elrayess, Steven C. Hunt, Stephen L. Atkin, Abdul-Badi Abou-Samra   +13 more
doaj   +1 more source

Genome-Wide Identification, Functional Analysis and Expression Profiling of the Aux/IAA Gene Family in Tomato [PDF]

, 2012
Auxin is a central hormone that exerts pleiotropic effects on plant growth including the development of roots, shoots, flowers and fruit. The perception and signaling of the plant hormone auxin rely on the cooperative action of several components,among
Abel, Abel, Abel, Bargmann, Carole Bassa, Chaabouni, Chaabouni, Corinne Audran-Delalande, Deng, Dharmasiri, Dharmasiri, Dreher, Eshed, Farid Regad, Finn, Hagen, Hamilton, Isabelle Mila, Jain, Jones, Kagale, Kalluri, Kepinski, Kloosterman, Leclercq, Li, Liscum, Mohamed Zouine, Mondher Bouzayen, Montgomery, Nebenführ, Oeller, Ohme-Takagi, Ottenschläger, Overvoorde, Paponov, Pirrello, Reed, Remington, Saitou, Sato, Szemenyei, Tamura, Tan, Theologis, Tiwari, Tiwari, Uehara, Ulmasov, Ulmasov, Wang, Wang, Wang, Wang, Yamamoto, Zuckerkandl   +55 more
core   +4 more sources

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

Time-Course Transcriptome Profiling Reveals Differential Resistance Responses of Tomato to a Phytotoxic Effector of the Pathogenic Oomycete Phytophthora cactorum

Plants, 2023
Blight caused by Phytophthora pathogens has a devastating impact on crop production. Phytophthora species secrete an array of effectors, such as Phytophthora cactorum-Fragaria (PcF)/small cysteine-rich (SCR) phytotoxic proteins, to facilitate their ...
Xue Zhou, Ke Wen, Shen-Xin Huang, Yi Lu, Yang Liu, Jing-Hao Jin, Shiv D. Kale, Xiao-Ren Chen   +7 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source