Results 111 to 120 of about 16,055,310 (231)

NbN Broadband Plasmonic Absorbers for Efficient Hot‐Carrier Injection Toward Improved Solar‐to‐Hydrogen Conversion

Advanced Science, EarlyView.
Niobium nitride (NbN) broadband plasmonic metasurface absorbers provide an efficient platform for solar‐energy conversion through hot‐carrier injection. Quasi‐epitaxial NbN features a low work function of 4.0 eV, reducing the interfacial injection barrier and facilitating charge transfer into adjacent photocatalysts.
Tzu‐Yu Peng, Tse‐Fu Huang, Takeshi Yamaguchi, Jia‐Wern Chen, Hsing‐Yu Kuo, Ying‐Rang Zhuang, Hung Wei Shiu, Seongmin Im, Yang Zhao, Takuo Tanaka, Ho‐Hsiu Chou, Yu‐Jung Lu   +11 more
wiley   +1 more source

Distinct Cleavage Trajectories Mediated by DNA and RNA Substrate in Argonaute From Methanocaldococcus Fervens

Advanced Science, EarlyView.
This study characterizes MfAgo, an enzyme exhibiting highly efficient DNA‐guided DNA and RNA cleavage capability. Precise RNA cleavage strictly requires dimerization to stabilize the PIWI‐loop region, while its robust DNA cleavage functions in a dimerization‐independent manner.
Fuyong Huang, Taiyu Chen, Meng Fang, Qinmiao Duanmu, Kangle Mu, Yuqi Bi, Siwei Xu, Xin Tao, Jiening Wang, Shan Wu   +9 more
wiley   +1 more source

Development and Characterization of Novel ELISAs for the Specific Quantification of the Factor H-Related Proteins 2, 3, 4, and 5

Journal of Innate Immunity
Introduction: The complement system’s alternative pathway relies on factor H (FH) for immune homeostasis. Next to FH, a group of highly similar proteins was described known as the FH-related (FHR) proteins.
Mara van Rossum, Bert R.J. Veuskens, Mieke C. Brouwer, Gerard van Mierlo, Laura Lucientes-Continente, Elena Goicoechea de Jorge, Barbara Uzonyi, Alexandra T. Matola, Mihály Józsi, Günter Müller, Anita M. Meter-Arkema, Felix Poppelaars, Diana Pauly, Richard B. Pouw, Erik J.M. Toonen   +14 more
doaj   +1 more source

Longitudinal Multifrequency MR Elastography Reveals Biomechanical Signatures of Progression in a Translational Liver Tumor Model

Advanced Science, EarlyView.
Longitudinal multifrequency magnetic resonance elastography (mMRE) performed on a clinical 3 Tesla magnetic resonance imaging system reveals early biomechanical alterations during liver tumor progression in a translational VX2 model. Changes in tumor stiffness and viscosity precede diffusion‐related alterations and are associated with extracellular ...
Justus Ramtke, Friederike Hesse, Lasse Noack, Justus Klockner, Yubei He, Yu Liu, Yanglei Wu, Robin Schmidt, Selma Saclier, Salma A. S. Abosabie, Tom Meyer, Richard Ruppel, Nikolaus Berndt, Michael Mülleder, Eyk Schellenberger, Nicola Beindorff, Dominik N. Müller, Ingolf Sack, Jing Guo, Shraga Nahum Goldberg, Lynn Jeanette Savic   +20 more
wiley   +1 more source

Self‐Assembling Peptide‐Adjuvant Conjugate (SaPAC) Platform for Precision Cancer Immunotherapy

Advanced Science, EarlyView.
A self‐assembling peptide–adjuvant conjugate links neoantigens to TLR7 agonism, forming cationic nanoparticles that enhance lymph‐node retention, dendritic‐cell activation, and antitumor T‐cell immunity. This chemically defined platform shows how synchronized antigen and innate stimulation can be adapted across melanoma, bladder cancer, and triple ...
Yang‐Fan Wu, Jing‐Chu Hu, Ye‐Fan Hu, Wen‐Jun Li, Li Rong, Ren‐Hao Li, Yuan Yao, Lehan Hu, Xiao‐Lei Wang, Bao‐Zhong Zhang, Yicheng Lu, Shing‐Fung Chow, Canhui Su, Thomas Yau, Clive Yik‐Sham Chung, Jian‐Dong Huang   +15 more
wiley   +1 more source

Impaired Immunogenicity of a Meningococcal Factor H-Binding Protein Vaccine Engineered To Eliminate Factor H Binding

, 2010
Meningococcal factor H-binding protein (fHbp) is a promising antigen that is part of two vaccines in clinical development. The protein specifically binds human complement factor H (fH), which downregulates complement activation on the bacterial surface ...
Sanjay Ram, Jutamas Shaughnessy, Peter T. Beernink, Dan M. Granoff   +3 more
core   +1 more source

SOX30 Facilitates Triple‐Negative Breast Cancer Metastasis via TNFR2–NF‐κB Signaling and Tumor Microenvironment Remodeling

Advanced Science, EarlyView.
SOX30 drives triple‐negative breast cancer (TNBC) metastasis through a dual mechanism: direct activation of the TNFR2/NF‐κB signaling cascade and subsequent CCL20‐mediated recruitment of tumor‐associated macrophages (TAMs) into the tumor microenvironment.
Pingping Gao, Na Sun, Ning Yang, Tingting Zhao, Rui Fu, Zhenyu Wu, Yuqin Zhou, Xuanni Tan, Yi Zhang, Fei Han, Xiaowei Qi   +10 more
wiley   +1 more source

A case of atypical hemolytic uremic syndrome with a transient decrease in complement factor H

, 2005
We report a case of sporadic atypical hemolytic uremic syndrome (HUS) with a transient decrease in complement factor H. Referred for hemolysis and azotemia without diarrhea prodrome, this 31-month-old boy showed a decreased complement 3 (C3) and ...
Park, Young Seo, Um, Eun Young, Hahn, Hyewon, Cheong, Hae Il   +3 more
core   +1 more source

High‐Current‐Density Acidic CO2 Electroreduction to Formic Acid Enabled by Multiscale Microenvironment Regulation Over Defect‐Rich Sn/SnOx

Advanced Science, EarlyView.
Acidic CO2 electroreduction to formic acid is enabled by integrating mixed Sn/SnOx nanoclusters, K+‐regulated interfacial solvation, and Janus wettability. Coordinated control of active sites, interfacial water, and gas‐liquid transport suppresses hydrogen evolution and delivers approximately 85% HCOOH Faradaic efficiency at 400 mA cm−2.
Qiaoqi Guo, Bowen Jiang, Le Huang, Kunyu Jiang, Rongrong Tang, Qinong Zhu, Huajun Feng, Mengyang Fan, Yijing Xia   +8 more
wiley   +1 more source

Corrigendum: A Family Affair: Addressing the Challenges of Factor H and the Related Proteins

Frontiers in Immunology, 2022
Felix Poppelaars, Elena Goicoechea de Jorge, Ilse Jongerius, Ilse Jongerius, Antje J. Baeumner, Mark-Steven Steiner, Mihály Józsi, Mihály Józsi, Erik J. M. Toonen, Diana Pauly, Diana Pauly, the SciFiMed consortium   +11 more
doaj   +1 more source