Results 91 to 100 of about 242,673 (264)
Macromolecular Bioscience, EarlyView.Heparin is postulated to possess antitumor properties‐ beyond its anticoagulative activities in oncology, but disclosure of targeted activities is complicated by heparins structural variabilities as natural glycosaminoglycans. Here, synthetic noncarbohydrate polymers are presented with tuneable structures as heparin mimetics in in‐vitro‐approaches for ...
Katrin Nekipelov +12 more
wiley +1 more source
Construction and Expression of Recombinant LL-37 as Histag-SUMO Fusion Protein with Factor Xa Cleavage Site [PDF]
LL-37 is an antimicrobial protein expressed by the CAMP gene in humans. This protein has various antibacterial, antiviral and anticancer effects. Expressing LL-37 as a heterologous protein in E. coli cells has its challenges.
Fadhlillah, Muhammad +3 more
core +2 more sources
Macromolecular Materials and Engineering, EarlyView.Representation of fabrication of carbon nanodots/platinum functionalized nanocomposite hydrogel formulation for near‐infrared responsive delivery of doxorubicin for lung cancer treatment. Abstract Lung cancer remains one of the deadliest cancers, marked by uncontrolled cell growth in the lungs and often diagnosed at later stages.
Xiaoqin An, Junjun Bai, Yuan Li
wiley +1 more source
Mass Spectrometry Reviews, EarlyView.Abstract Affinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on the identification of peptide partners using photoaffinity labeling coupled to mass spectrometry in different contexts such as in vitro with a
Astrid Walrant, Emmanuelle Sachon
wiley +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT Dielectric barrier discharge ionization (DBDI) sources, employing low‐temperature plasma, have emerged as sensitive and efficient ionization tools with various atmospheric pressure ionization processes. In this review, we summarize a historical overview of the development of DBDI, highlighting key principles of gas‐phase ion chemistry and the ...
Kseniya Dryahina +4 more
wiley +1 more source
Antithrombin: Deficiency, Diversity, and the Future of Diagnostics
Mass Spectrometry Reviews, EarlyView.ABSTRACT Our healthcare system provides reactive sick‐care, treating patients after symptoms have appeared by prescription of generic and often suboptimal therapy. This strategy brings along high costs and high pressure which is not sustainable.
Mirjam Kruijt +2 more
wiley +1 more source
Factor Xa inhibitors in hemodialysis: OK-for now! [PDF]
Proc (Bayl Univ Med Cent), 2023 Banchs JE.
europepmc +1 more source
Regimes and Mechanisms of Inflammation Described by a Reaction–Diffusion System
Mathematical Methods in the Applied Sciences, EarlyView.ABSTRACT Inflammation is a biological response of the immune system to external stimuli such as injury or infection. It plays an important role in various diseases including atherosclerosis, cancer, and neurodegenerative diseases. This work presents a generic inflammation model based on reaction–diffusion equations that describes the concentrations of ...
W. El Hajj, N. El Khatib, V. Volpert
wiley +1 more source
Molecular Nutrition &Food Research, EarlyView.(Poly)phenols constitute a source of natural therapeutic molecules capable of targeting angiogenesis in different scenarios. This review summarizes the current evidence of the role of (poly)phenols in modulating angiogenesis. The reader can find a compilation of preclinical and human investigations describing pro‐ and anti‐angiogenic effects of these ...
María Ángeles Ávila‐Gálvez +5 more
wiley +1 more source
Social mechanics of gifting bear bile in Việt Nam
People and Nature, EarlyView.Abstract The illegal wildlife trade is a major cause of global diversity loss. In Southeast Asia and particularly in Việt Nam, the consumption of wildlife products is mostly driven by demand for food and traditional medicine products. One key example of this in Việt Nam is the use of bear bile. While bear bile is one of the most well‐researched illegal
Elizabeth Oneita Davis +2 more
wiley +1 more source