Measuring Direct Oral Anticoagulant (DOAC) Levels: Applications, Limitations, and Future Directions
ABSTRACT Introduction There are important challenges with the measurement and interpretation of direct oral anticoagulant (DOAC) anticoagulant effect including a lack of therapeutic ranges, inaccuracy of routinely available coagulation assays, lack of established thresholds for clinically significant effect, and uncertainty about how to apply the ...
Siraj Mithoowani +2 more
wiley +1 more source
Effects of DOACs on Mouse Melanoma Metastasis and the Inhibitory Mechanism of Edoxaban, a Factor Xa-Specific DOAC. [PDF]
Hiramoto K +3 more
europepmc +1 more source
Abstract The retrogressive thaw slumps (RTS), a prevalent form of thermokarst hazard in permafrost regions, are increasing in both number and extent under contemporary changing environments. On the Qinghai‐Tibet Plateau, RTS threaten transportation infrastructure and disrupt ecosystems.
Yuanzhuo Zhou +5 more
wiley +1 more source
Interfacial Atomic and Electronic Structures of LSM/YSZ Thin Films as Models for SOC Air Electrodes
Lanthanum–strontium manganite/yttria‐stabilized zirconia thin films serve as model systems for solid oxide cell electrodes, where high‐resolution scanning transmission electron microscopy and X‐ray photoelectron spectroscopy reveal atomistic interfacial features and electronic structure supported by atomistic modeling of these interfaces.
Hebatallah Ali +18 more
wiley +1 more source
Andexanet alfa vs standard of care for factor Xa inhibitor-induced intracranial hemorrhage-a systematic review and meta-analysis. [PDF]
Xiang AJ +7 more
europepmc +1 more source
The implementation of crown ethers into the ligand of cobalt porphyrins benefits the electrochemical CO2 reduction in the several ways: (1) the reduction potential is lowered in presence of K+; (2) it boosts the CO generation in Zero‐Gap Electrolyzers and (3) ensures complex stability during electrolysis.
Wiebke Wiesner +7 more
wiley +1 more source
Position statement of the Polish Society of Gastroenterology on the use of andexanet alfa in patients with gastrointestinal bleeding taking factor Xa inhibitors. [PDF]
Adrych K +4 more
europepmc +1 more source
Biohybrid Tendons Enhance the Power‐to‐Weight Ratio and Modularity of Muscle‐Powered Robots
Biohybrid robots powered by skeletal muscle actuators are capable of dynamically adapting to environmental cues. This study takes inspiration from native muscle–tendon architecture by leveraging tough hydrogels as synthetic tendons for muscle actuators to enhance the power‐to‐weight ratio and modularity of biohybrid machines.
Nicolas Castro +11 more
wiley +1 more source
Peak and Trough Concentration Ranges of Factor Xa Inhibitors for Preventing Thromboembolic Stroke in Korean Patients with Non-valvular Atrial Fibrillation. [PDF]
Park JS +5 more
europepmc +1 more source

