Transcriptional memory emerges from cooperative histone modifications [PDF]
, 2011 Background Transcriptional regulation in cells makes use of diverse mechanisms to ensure that functional states can be maintained and adapted to variable environments; among them are chromatin-related mechanisms.
Hans Binder +4 more
core +1 more source
The Attentional Routing Circuit: Receptive Field Modulation Through Nonlinear Dendritic Interactions [PDF]
, 2011 We present a model of attentional routing called the Attentional Routing Circuit (ARC) that extends an existing model of spiking neurons with dendritic nonlinearities. Specifically, we employ the Poirazi et al.
Bruce Bobier +2 more
core +2 more sources
FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron
Advanced Science, EarlyView.This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang +14 more
wiley +1 more source
An evidence-based review of edoxaban and its role in stroke prevention in patients with nonvalvular atrial fibrillation. [PDF]
, 2015 Atrial fibrillation is the most common arrhythmia in the elderly. It is responsible for significant morbidity and mortality from cardioembolic complications like stroke.
Acharya, Tushar, Deedwania, Prakash
core +1 more source
Advanced Science, EarlyView.A calcium‐dependent, specific biorecognition between coagulation factor Xa (FXa) and zeolite is discovered. It alters the prothrombin activation pathway to a more efficient mechanism by mimicking the FXa/factor Va (FXa/FVa) interaction formed during the natural coagulation cascade.
Chaojie Shi +9 more
wiley +1 more source
Fuzzy logic as a decision-making support system for the indication of bariatric surgery based on an index (OBESINDEX) generated by the association between body fat and body mass index [PDF]
, 2011 Background: A Fuzzy Obesity Index (OBESINDEX) for use as an alternative in bariatric surgery indication (BSI) is presented. The search for a more accurate method to evaluate obesity and to indicate a better treatment is important in the world health ...
Glicia C. Azevedo +6 more
core +1 more source
Effect of a single Dialysis session on plasma Lp(a) levels in patients on Maintenance haemodialysis [PDF]
, 2011 Background: Cardiovascular disease (CVD) is a major cause of mortality in End stage renal disease (ESRD) patients on Maintenance haemodialysis (MHD).
Aparna R. Bitla +5 more
core +1 more source
Advanced Science, EarlyView.BaTiO3‐based polymorphic relaxor ferroelectrics are engineered by mesoscopically chemical homogeneity, constructing diversified nanodomain architectures with similar multiple local symmetries but different nanodomain scales in diverse grains. Ex‐/In situ multiscale structure analysis indicates that a relatively continuous polarization switching with ...
Aiwen Xie +10 more
wiley +1 more source
Comparison of coagulation factor Xa and des-(1-44)factor Xa in the assembly of prothrombinase.
Journal of Biological Chemistry, 1984 The gamma-carboxyglutamic acid (Gla)-domain region of factor X (residues 1-44 of the light chain) was selectively removed by limited proteolysis with alpha-chymotrypsin. The Gla-domainless factor X was then activated by the factor X coagulant protein of Russell's viper venom.
W F Skogen, A C Cox, C T Esmon
openaire +3 more sources
Spintronic Memtransistor Leaky Integrate and Fire Neuron for Spiking Neural Networks
Advanced Electronic Materials, EarlyView.Spintronic memtransistor neurons based on domain walls enable energy‐efficient, field‐gated, and current‐controlled LIF functionality for neuromorphic computing, as demonstrated. When integrated into spiking neural network architectures, these devices achieve >96% pattern recognition accuracy, demonstrating high performance, scalability, and mem ...
Aijaz H. Lone +7 more
wiley +1 more source