Results 81 to 90 of about 242,673 (264)

Chronic hyperplastic anemia as an independent risk factor for atherosclerotic lesions: a lesson from thalassemia intermedia [PDF]

open access: yes, 2010
Introduction. Cardiovascular involvement represents a well-known complication and the primary cause of mortality, both in transfusion-dependent beta thalassemia major (β-TM) and in transfusion-independent beta thalassemia intermedia (β-TI ...
Alessandra Spiga   +7 more
core   +1 more source

Percutaneous mechanical circulatory support for acute right heart failure: A practical approach

open access: yesESC Heart Failure, EarlyView.
This is an overview of percutaneous mechanical circulatory support options for acute right heart failure, illustrating key clinical scenarios, device types, and principles of tailored device selection based on haemodynamics and underlying pathology. Abstract Acute right heart failure (RHF) represents a critical entity with significant morbidity and ...
Mario Gramegna   +18 more
wiley   +1 more source

Baseline characteristics of contemporary trial participants with heart failure and reduced ejection fraction: The VICTOR trial

open access: yesEuropean Journal of Heart Failure, EarlyView.
Baseline characteristics for the vericiguat global study in participants with chronic heart failure (VICTOR) trial. ARNI, angiotensin receptor/neprilysin inhibitor; CRT, cardiac resynchronization therapy; eGFR, estimated glomerular filtration rate; GDMT, guideline‐directed medical therapy; HF, heart failure; HFrEF, heart failure with reduced ejection ...
Clara I. Saldarriaga   +21 more
wiley   +1 more source

An Optimized Power Load Forecasting Algorithm Based on VMD‐SMA‐LSTM

open access: yesEnergy Science &Engineering, EarlyView.
This paper proposes a load forecasting method that successfully combines the VMD‐SMA‐LSTM algorithms for load forecasting, and compares it with existing methods, demonstrating the superiority of the algorithm. ABSTRACT Accurate load forecasting can scientifically guide the optimal operation and scheduling of urban power grids.
Wei Liu   +4 more
wiley   +1 more source

The Impact of Augmented Renal Clearance on the Pharmacokinetics of Levetiracetam in Critically Ill Patients: A Literature Review

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Levetiracetam is an antiseizure medication (ASM) that has several advantages over other ASMs, such as dose‐proportional pharmacokinetics, high bioavailability, and minimal drug interactions. The drug is primarily eliminated through the kidneys. Therefore, dose adjustments are necessary in patients with renal impairment or patients experiencing
Maged Kharouba   +3 more
wiley   +1 more source

MEMOFinder: combining _de_ _novo_ motif prediction methods with a database of known motifs [PDF]

open access: yes, 2008
*Background:* Methods for finding overrepresented sequence motifs are useful in several key areas of computational biology. They aim at detecting very weak signals responsible for biological processes requiring robust sequence identification like ...
Bartek Wilczynski   +2 more
core   +2 more sources

Livedoid Vasculopathy Successfully Treated With JAK Inhibitors

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Livedoid vasculopathy is a rare thrombotic disease of the small blood vessels. It manifests as fixed violaceous macules, noninflammatory retiform purpura, painful ulcers, and white atrophic scars on the lower extremities. The pathophysiology involves the type 1 interferon pathway. Many patients do not improve with oral anticoagulants.
Antoine Delpuech   +7 more
wiley   +1 more source

Structural Requirements for Expression of Factor VA Activity [PDF]

open access: yes, 2003
Thrombin activated factor Va (factor VIIa, residues 1-709 and 1546-2196) has an apparent dissociation constant (Kd,app) for factor Xa within prothrombinase of approximately 0.5 nM.
Beck, Daniel O   +2 more
core   +1 more source

RADA‐16 Reduces Postoperative Epistaxis After Inferior Turbinate Submucosal Resection

open access: yesThe Laryngoscope, EarlyView.
RADA‐16 is a self‐assembling peptide matrix that forms a hydrogel structure, showing potential for enhanced wound healing and hemostasis. In this retrospective cohort study, postoperative bleeding rates were compared between patients treated with RADA‐16 and those without, demonstrating an association between RADA‐16 use and decreased rates of ...
Annie Xu   +6 more
wiley   +1 more source

Drivers of dissolved organic matter processing in subterranean estuaries

open access: yesLimnology and Oceanography Letters, EarlyView.
Abstract Subterranean estuaries (i.e., seawater‐fresh groundwater mixing zones at coastal aquifers) are highly reactive boundaries between continental groundwater and coastal surface seawater. Because particulate organic matter is retained in shallow sediments, internal microbial transformations rely on dissolved organic matter (DOM) supply and ...
Elisa Calvo‐Martin   +4 more
wiley   +1 more source

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