Results 111 to 120 of about 2,920,145 (314)
Clinician to Medical Teacher: Perspectives for the First Year
MedEdPublish, 2021 Practicing physicians may follow the desire to enter full-time academic medicine as a clinician-educator. There is a paucity of literature to inform the clinician with a successful framework in transitioning to all the necessary roles encountered as a ...
Robert Tyler +4 more
doaj
Resident Physicians' Preparedness to Provide Cross-Cultural Care: Implications for Clinical Care and Medical Education Policy [PDF]
, 2007 Recommends integrating cross-cultural training into medical school curricula, training faculty to ensure useful instruction and mentoring, and mandatory and formal evaluation of residents' cross-cultural communication ...
Joel S. Weissman +2 more
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Student Perceptions of the Professional Behavior of Faculty Physicians [PDF]
, 2003 This study was conducted to obtain a baseline understanding of the professional behavior of clinical faculty physicians from the medical students’ perspective.
Ainsworth ,MD, Michael A. +5 more
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Revista Brasileira de Educação MédicaRESUMO A avaliação programática do estudante é uma abordagem relativamente nova, que tem como objetivo principal o aperfeiçoamento das condições de utilização dos diferentes métodos de avaliação, com vistas ao melhor cumprimento das funções da avaliação:
Luiz Ernesto de Almeida Troncon
doaj +1 more source
Annual Performance Reviews Of, For and By Faculty: A Qualitative Analysis of One Department's Experiences [PDF]
, 2018 Purpose: Although annual performance reviews and feedback are recommended for faculty development, best practices and faculty perceptions have not been documented.
Connelly, Maureen T. +3 more
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source