Results 31 to 40 of about 10,130,145 (265)

Concepções do processo ensino-aprendizagem: um estudo com professores de medicina

Revista Brasileira de Educação Médica
Este artigo aborda a docência médica como um processo de construção social, que articula condicionantes político-acadêmicos, pedagógicos, pessoais e intersubjetivos.
Angela Maria Moreira Canuto, Sylvia Helena Souza da Silva Batista   +1 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Ten tips to effectively engage community-based preceptors in distributed medical education settings

Journal of Regional Medical Campuses
The effective engagement of community-based preceptors in distributed medical education (DME) settings is an active challenge in medical education. DME is a model of medical education that involves training medical students in multiple, geographically ...
Aaron Johnston, Grace Perez, Rebecca Malhi, Amanda Bell   +3 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Faculty Development Interventions in Medical Education During the COVID-19 Pandemic: A Systematic Review

Education Sciences
The onset of the COVID-19 pandemic in March 2020 began a series of disruptions that rapidly impacted medical education across the globe. This review collates current literature that relates to medical education faculties’ development interventions as a ...
Hengameh Karimi, Sarwar Khawaja
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Medical student and medical school teaching faculty perceptions of conflict of interest

BMC Research Notes, 2017
Background Attitudes towards conflict of interest (COI) and COI policy are shaped during medical school and influence both the education of medical students and their future medical practice.
Nicholas S. Andresen, Tyler S. Olson, Matthew D. Krasowski   +2 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Destacadas personalidades de la dermatología tropical en el Perú

Revista Peruana de Medicina Experimental y Salud Pública
En este artículo se rinde homenaje a tres personalidades médicas peruanas: José Neyra Ramírez (1929-2012), Abelardo Tejada (1931-2013) y Oscar Romero Rivas (1929-2011), se destaca sus valiosas contribuciones en el campo de la Dermatología Tropical y de ...
Zuño Burstein Alva
doaj   +2 more sources