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Imaging Brain Fatty Acid Amide Hydrolase in Untreated Patients With Psychosis. [PDF]
Watts JJ +10 more
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Fatty acid amide hydrolase (FAAH); monoacylglycerol lipase (MAGL) [PDF]
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Inhibition of fatty acid amide hydrolase exerts cutaneous anti-inflammatory effects both in vitro and in vivo [PDF]
Abels, Christoph +8 more
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Fatty Acid Amide Hydrolase: An Integrative Clinical Perspective
Cannabis and Cannabinoid Research, 2023Introduction: Fatty acid amide hydrolase (FAAH) is one of the main terminating enzymes of the endocannabinoid system (ECS). Since being discovered in 1996, the modulation of FAAH has been viewed as a compelling alternative strategy to obtain the beneficial effect of the ECS.
Anugrah D. Santoso, Dirk De Ridder
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Fatty acid amide hydrolase substrate specificity
Bioorganic & Medicinal Chemistry Letters, 2000Fatty acid amide hydrolase (FAAH), also referred to as oleamide hydrolase and anandamide amidohydrolase, is a serine hydrolase responsible for the degradation of endogenous oleamide and anandamide, fatty acid amides that function as chemical messengers.
D L, Boger +5 more
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Anandamide amidohydrolase (fatty acid amide hydrolase)
Prostaglandins & Other Lipid Mediators, 2000Anandamide (N-arachidonoylethanolamine) loses its cannabimimetic activity when it is hydrolyzed to arachidonic acid and ethanolamine by the catalysis of an enzyme referred to as anandamide amidohydrolase or fatty acid amide hydrolase. Cravatt's group and our group cloned cDNA of the enzyme from rat, human, mouse and pig, and the primary structures ...
N, Ueda, S, Yamamoto
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The fatty acid amide hydrolase (FAAH)
Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA), 2002The fatty acid amide hydrolase (FAAH), is the enzyme responsible for the hydrolysis of anandamide, an endocannabinoid. The FAAH knockout, the assays for FAAH, the activity of its substrates, its reversibility and its cloning from rat, mouse, human, and pig are covered in this review.
D G, Deutsch, N, Ueda, S, Yamamoto
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The fatty acid amide hydrolase (FAAH)
Chemistry and Physics of Lipids, 2000The topic of this review is fatty acid amide hydrolase (FAAH), one of the best-characterized enzymes involved in the hydrolysis of bioactive lipids such as anandamide, 2-arachidonoylglycerol (2-AG), and oleamide. Herein, we discuss the nomenclature, the various assays that have been developed, the relative activity of the various substrates and the ...
N, Ueda +3 more
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