Results 161 to 170 of about 13,359 (214)

4,4-Dimethylsterols Reduces Fat Accumulation via Inhibiting Fatty Acid Amide Hydrolase In Vitro and In Vivo. [PDF]

Research (Wash D C)
Zhang T, Xie L, Guo Y, Wang Z, Guo X, Liu R, Jin Q, Chang M, Wang X.   +8 more
europepmc   +1 more source

Fatty acid amide hydrolase activity in the dorsal periaqueductal gray attenuates neuropathic pain and associated dysautonomia.

Am J Physiol Regul Integr Comp Physiol, 2022
Woyach V, Sherman K, Hillard CJ, Hopp FA, Hogan QH, Dean C.   +5 more
europepmc   +1 more source

The efficacy of elevating anandamide via inhibition of fatty acid amide hydrolase (FAAH) combined with internet-delivered cognitive behavioral therapy in the treatment of post-traumatic stress disorder: a randomized, placebo-controlled clinical trial. [PDF]

Neuropsychopharmacology
Mayo LM, Gauffin E, Petrie GN, Tansey R, Mazurka R, Haggarty CJ, Jones MR, Engelbrektsson H, Aminoff V, Hühne-Landgraf A, Schmidt ME, Pemberton DJ, Fredlund C, Östman L, Karlsson H, Löfberg A, Pietrzak M, Andersson G, Capusan AJ, Hill MN, Heilig M.   +20 more
europepmc   +1 more source

Efficacy and safety of JNJ-42165279, a fatty acid amide hydrolase inhibitor, in adolescents and adults with autism spectrum disorder: a randomized, phase 2, placebo-controlled study. [PDF]

Neuropsychopharmacology
Klein ME, Bangerter A, Halter RJ, Cooper K, Aguilar Z, Canuso CM, Drevets WC, Schmidt ME, Pandina G.   +8 more
europepmc   +1 more source

4-Phenyl-thiazole-based dual inhibitors of fatty acid amide hydrolase and soluble epoxide hydrolase do not alleviate orofacial inflammatory pain in female rats. [PDF]

BBA Adv
Carr D, Chin C, Chacon T, Herawi MK, Gonzalez M, West R, Morisseau C, Hammock BD, Pecic S, Kandasamy R.   +9 more
europepmc   +1 more source

Evaluating Fatty Acid Amide Hydrolase as a Suitable Target for Sleep Promotion in a Transgenic TauP301S Mouse Model of Neurodegeneration. [PDF]

Pharmaceuticals (Basel)
Martin SC, Joyce KK, Harper KM, Harp SJ, Cohen TJ, Moy SS, Diering GH.   +6 more
europepmc   +1 more source

Effect of MCH1, a fatty-acid amide hydrolase inhibitor, on the depressive-like behavior and gene expression of endocannabinoid and dopaminergic-signaling system in the mouse nucleus accumbens. [PDF]

Braz J Med Biol Res
Medina-Saldivar C, Pardo GVE, Pacheco-Otalora LF.   +2 more
europepmc   +1 more source

Fatty Acid Amide Hydrolase: From Characterization to Therapeutics

Chemistry and Biodiversity, 2007
AbstractFatty acid amide hydrolase (FAAH) is an integral membrane enzyme within the amidase‐signature family that terminates the action of several endogenous lipid messengers, including oleamide and the endocannabinoid anandamide. The hydrolysis of such messengers leads to molecules devoid of biological activity, and, therefore, modulates a number of ...
Geoffray Labar, Catherine Michaux
exaly   +5 more sources