Results 91 to 100 of about 2,751,456 (226)

Functional characterisation of two cytochrome b 5-fusion desaturases from Anemone leveillei : the unexpected identification of a fatty acid delta6-desaturase

, 2003
The Ranunculaceae are known to accumulate a wide range of unusual fatty acids in their seed lipids, and this variability has been advocated as a taxonomic marker. The Anemone species, Anemone leveillei L. and Anemone rivularis Buch.-Ham., have previously
Pickett, J. A., Sayanova, Olga, Sayanova, O. V., Michaelson, L. V., Michaelson, Louise V., Napier, Johnathan A., Napier, J. A., Whitney, Heather M., Whitney, H. M., Pickett, John A.   +9 more
core   +1 more source

In Vitro Versus in Situ Ruminal Biohydrogenation of Unsaturated Fatty Acids from a Raw or Extruded Mixture of Ground Canola Seed/Canola Meal [PDF]

, 2003
Raw or extruded blends of ground canola seeds and canola meal were used to compare in vitro and in situ lag times and rates of disappearance due to ruminal biohydrogenation of unsaturated fatty acids.
Moncoulon, R., Troegeler-Meynadier, Annabelle, Eynard, P., Bayourthe, Corine, Nicot, M.C., Enjalbert, Francis, Eynard, Philippe, Nicot, Marie-Claude, Bayourthe, C., Troegeler-Meynadier, A., Enjalbert, F.   +10 more
core   +1 more source

In planta analysis of the mode of action of cinmethylin and confirmation of fatty acyl‐ACP thioesterases (FATs) as primary site of action

Pest Management Science, EarlyView.
In planta analysis of the mode of action of cinmethylin and confirmation of fatty acyl‐ACP thioesterases (FATs) as primary site of action. Cinmethylin inhibits FATs, disrupting eukaryotic de novo lipid biosynthesis and causing defects in cell division, elongation and integrity. We confirm FATs as the primary site of action in planta.
Maximillian Pollmeier, Aisha Gerhardt, Janneke Hendriks, Katharina Kaprocki, Alexandra Zimmermann, Sarina Ruehm, Martina Marnet, Maria Stroe, Jorge Alfredo Rojas Biava, Clara Hofmann, Michael Betz, Sascha Schlaefer, Philipp Ternes, Jens Lerchl, Selene Garcia‐Hernandez, Philipp Johnen   +15 more
wiley   +1 more source

Δ-6 Desaturase substrate competition: dietary linoleic acid (18:2n-6) has only trivial effects on α-linolenic acid (18:3n-3) bioconversion in the teleost rainbow trout.

PLoS ONE, 2013
It is generally accepted that, in vertebrates, omega-3 (n-3) and omega-6 (n-6) poly-unsaturated fatty acids (PUFA) compete for Δ-6 desaturase enzyme in order to be bioconverted into long-chain PUFA (LC-PUFA).
James A Emery, Karen Hermon, Noor K A Hamid, John A Donald, Giovanni M Turchini   +4 more
doaj   +1 more source

Multi‐Target Pharmacological Mechanisms of Salvia miltiorrhiza Bunge in Metabolic Syndrome and Cardiovascular Diseases: A Comprehensive Review Based on the Theory of “Same Treatment for Different Diseases”

Phytotherapy Research, EarlyView.
Salvia miltiorrhiza Bunge in metabolic syndrome and cardiovascular diseases: multi‐target actions on shared signaling pathways. ABSTRACT Metabolic syndrome (MetS) represents a clinical disorder characterized by the clustering of conditions including obesity, elevated blood sugar levels, and high lipid levels, which are intricately linked to the onset ...
Zhiyi Jia, Kaiyi Wu, Jiaying Qi, Nana Huang, Yusheng Liu, Xiumei Gao, Rong Sun   +6 more
wiley   +1 more source

Acid-exposed and hypoxic cancer cells do not overlap but are interdependent for unsaturated fatty acid resources

Nature Communications
Cancer cells in acidic tumor regions are aggressive and a key therapeutic target, but distinguishing between acid-exposed and hypoxic cells is challenging.
Katarzyna Głowacka, Sébastien Ibanez, Ophélie Renoult, Perrine Vermonden, Maria Virginia Giolito, Kübra Özkan, Charline Degavre, Léo Aubert, Céline Guilbaud, Florine Laloux-Morris, Elena Richiardone, Jérôme Ambroise, Caroline Bouzin, Davide Brusa, Jonas Dehairs, Johan Swinnen, Cyril Corbet, Yvan Larondelle, Olivier Feron   +18 more
doaj   +1 more source

Effect of dietary supplementation with conjugated linoleic acid on markers of calcium and bone metabolism in healthy adult men.

, 2005
INTRODUCTION: Conjugated linoleic acid (CLA) has been shown to positively influence calcium and bone metabolism in experimental animals and cells in culture, but there are limited human data available.
Mullen, A, Cashman, KD, Jewell, C, Roche, HM, Doyle, L, Nugent, AP   +5 more
core   +1 more source

Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine

Phytotherapy Research, EarlyView.
By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao, Huiming Huang, Xuejiao Wei, Xiaoxue Wang, Wanying Xie, Xinyu Qiu, Fei Wang, Zhuguo Wang, Ruoxin Zhang, Yilin Cai, Changhai Qu, Zhongdong Hu   +11 more
wiley   +1 more source

Effects of glucagon and dibutyryl adenosine 3‘, 5‘-cyclic monophosphate on oxidative desaturation of fatty acids in the rat

Journal of Lipid Research, 1975
The present work was undertaken to study the effect of anti-insulinic and glycogenolytic factors on the oxidative desaturation of fatty acids. The effects of glucagon and dibutyryl cyclic AMP on the desaturation of linoleic acid to γ-linolenic acid, α ...
I.N. de Gómez Dumm, M.J. de Alaniz, R.R. Brenner   +2 more
doaj   +1 more source

Ozone‐driven degradation of sex pheromone in Plutella xylostella: Implications for reproductive communication and mating success

Insect Science, EarlyView.
In this study, we examined whether realistic ozone concentrations can interfere with sexual communication in the insect pest Plutella xylostella, the diamondback moth. Ozone exposure caused a degradation of pheromone components, leading to significant changes in blend composition and component ratios.
Francesco Sorrentino, Delia M. Pinto‐Zevallos, Oksana Skaldina, James D. Blande   +3 more
wiley   +1 more source