Results 81 to 90 of about 39,692 (272)

Heavy ion mutagenesis combined with triclosan screening provides a new strategy for improving the arachidonic acid yield in Mortierella alpina

BMC Biotechnology, 2018
Background Arachidonic acid (ARA), which is a ω-6 polyunsaturated fatty acid, has a wide range of biological activities and is an essential component of cellular membranes in some human tissues.
Huidan Zhang, Dong Lu, Xin Li, Yingang Feng, Qiu Cui, Xiaojin Song   +5 more
doaj   +1 more source

Investigations into β-ketoacyl-ACP Synthase III and enoyl-ACP reductase of plant fatty acid synthase [PDF]

, 1999
An antisense transgenic approach was taken in order to assess the importance of P-ketoacyl-ACP- Synthase III (KAS III) in regulation and initiation of de novo fatty acid synthesis in planta.
Clarke, Hayley Diana
core  

Functional identification of a fatty acid Δ5 desaturase gene from Caenorhabditis elegans

, 1998
We have identified a cDNA from the nematode worm Caenorhabditis elegans that encodes a fatty acid Δ5 desaturase. Saccharomyces cerevisiae expressing the full-length cDNA was able to convert di-homo-γ-linolenic acid to arachidonic acid, thus confirming Δ5
Lewis, Mervyn, Michaelson, L. V., Napier, Johnathan A., Mervyn Lewis, Colin M. Lazarus, Griffiths, Gareth, Lazarus, Colin M., Lazarus, C. M., Johnathan A. Napier, Michaelson, Louise V., Louise V. Michaelson, Stobart, A. K., Stobart, A.Keith, A.Keith Stobart, Napier, J. A., Griffiths, G., Gareth Griffiths, Lewis, M.   +17 more
core   +1 more source

Inverse Association between trans Isomeric and Long-Chain Polyunsaturated Fatty Acids in Pregnant Women and Their Newborns: Data from Three European Countries [PDF]

, 2011
Background: trans unsaturated fatty acids are thought to interfere with essential fatty acid metabolism. To extend our knowledge of this phenomenon, we investigated the relationship between trans isomeric and long-chain polyunsaturated fatty acids ...
Krauss-Etschmann, S., É. Szabó, Marosvolgyi, Tamas, Campoy, C., T. Marosvölgyi, Decsi, Tamás, Marosvölgyi, T., C. Campoy, B. Koletzko, M. Escolano, Campoy, Cristina, Cruz, M., Szabó, É., Krauss-Etschmann, Susanne, S. Krauss-Etschmann, M. Cruz, Szabo, Eva, Escolano, M., Marchal, G., T. Decsi, Koletzko, Berthold, H. Demmelmair, Demmelmair, Hans, G. Marchal   +23 more
core   +1 more source

Selection in Europeans on Fatty Acid Desaturases Associated with Dietary Changes [PDF]

Molecular Biology and Evolution, 2017
FADS genes encode fatty acid desaturases that are important for the conversion of short chain polyunsaturated fatty acids (PUFAs) to long chain fatty acids. Prior studies indicate that the FADS genes have been subjected to strong positive selection in Africa, South Asia, Greenland, and Europe.
Buckley, Matthew T., Racimo, Fernando, Allentoft, Morten E., Jonsson, Anna, Huang, Hongyan, Hormozdiari, Farhad, Sikora, Martin, Marnetto, Davide, Eskin, Eleazar, Jørgensen, Marit E., Grarup, Niels, Pedersen, Oluf, Hansen, Torben, Willerslev, Eske, Nielsen, Rasmus, Jensen, Majken, Kraft, Phillip   +16 more
openaire   +6 more sources

Oocyte–cumulus cell interaction: a key factor in early embryo development

Biological Reviews, EarlyView.
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido, Marc Yeste, Yentel Mateo‐Otero   +2 more
wiley   +1 more source

The cytoprotective effects of Δ-17 fatty acid desaturase on injured HUVECs and its underlying mechanism

Saudi Pharmaceutical Journal, 2017
Endothelium toxicity has been involved in early endothelial dysfunction to show the pathogenesis of multiple cardiovascular disease that shows atherosclerosis and its complications.
Xiulan Zhang, Shixin Xia, Qiqi Xu, Jiandong Huang   +3 more
doaj   +1 more source

Highly unsaturated fatty acid synthesis in marine fish: Cloning, functional characterization, and nutritional regulation of fatty acyl delta6 desaturase of Atlantic cod (Gadus morhua L.) [PDF]

, 2006
Fish contain high levels of the n-3 highly unsaturated fatty acids (HUFA), eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids that are crucial to the health of higher vertebrates.
Tocher, Douglas R, Zheng, Xiaozhong, Xiaozhong Zheng, Hastings, Nicola, James R. Dick, Schlechtriem, Christian, Dick, James R, Nicola Hastings, Douglas R. Tocher, Christian Schlechtriem, Alan J. Teale   +10 more
core   +1 more source

Analysis of Δ12-fatty acid desaturase function revealed that two distinct pathways are active for the synthesis of PUFAs in T. aureum ATCC 34304

Journal of Lipid Research, 2012
Thraustochytrids are known to synthesize PUFAs such as docosahexaenoic acid (DHA). Accumulating evidence suggests the presence of two synthetic pathways of PUFAs in thraustochytrids: the polyketide synthase-like (PUFA synthase) and desaturase/elongase ...
Takanori Matsuda, Keishi Sakaguchi, Rie Hamaguchi, Takumi Kobayashi, Eriko Abe, Yoichiro Hama, Masahiro Hayashi, Daiske Honda, Yuji Okita, Shinichi Sugimoto, Nozomu Okino, Makoto Ito   +11 more
doaj   +1 more source

Kefir Grains Change Fatty Acid Profile of Milk during Fermentation and Storage. [PDF]

PLoS ONE, 2015
Several studies have reported that lactic acid bacteria may increase the production of free fatty acids by lipolysis of milk fat, though no studies have been found in the literature showing the effect of kefir grains on the composition of fatty acids in ...
C P Vieira, T S Álvares, L S Gomes, A G Torres, V M F Paschoalin, C A Conte-Junior   +5 more
doaj   +1 more source