Results 111 to 120 of about 39,848 (282)

Elevation of Stearoyl‐Coenzyme A Desaturase and Monounsaturated Fatty Acids in Parkinson's Disease Serum

Movement Disorders, EarlyView.
Abstract Background Emerging evidence indicates that dysregulation of monounsaturated fatty acids (MUFAs), synthesized by the enzyme stearoyl‐coenzyme A desaturase (SCD), impacts on α‐synuclein pathology in the Parkinson's disease (PD) brain. Objective The objective of this study was to analyze SCD and MUFA‐enriched lipids in the periphery of patients ...
Finula I. Isik, Russell Pickford, Michelle Chua, Simon J.G. Lewis, Nicolas Dzamko, Woojin Scott Kim   +5 more
wiley   +1 more source

Continental accumulation of fads2 copy numbers allows sticklebacks to thrive across a diversity of nutritional landscapes

Oikos, EarlyView.
Nutrients, including vital organic compounds, vary in availability across ecosystems, with the potential to act as a source of selection for traits that increase nutrient acquisition and biosynthesis. Compared to freshwaters, marine ecosystems are richer in the omega‐3 long‐chain polyunsaturated fatty acid (n‐3 LC‐PUFA) docosahexaenoic acid (DHA ...
Cornelia W. Twining, Cameron M. Hudson, Jernej Bravničar, Antonella Carosi, Gaël P. J. Denys, Philine G. D. Feulner, Žiga Fišer, Hanna Rosinger, Verena Saladin, Linda Zanella, Davor Zanella, Catherine L. Peichel, Blake Matthews   +12 more
wiley   +1 more source

Lipodystrophy and adipose tissue recovery are mediated by the Wnt/lipogenesis axis during skin fibrosis

The Journal of Pathology, EarlyView.
Abstract Acquired lipodystrophy in the dermal white adipose tissue (DWAT) is an early phenotype of skin fibrosis, followed by the accumulation of extracellular matrix (ECM). Lipodystrophy syndromes are estimated to affect 1 in 20,000 people and are associated with metabolic comorbidities.
Suneeti R Madhavan, Piper Moore, Rohan Varshney, Miles Montegut, Qiannan Ma, Kayla Klatt, Reshmi Parameswaran, Elif G Ertugral, Chandrasekhar R Kothapalli, Michael C Rudolph, Radhika P Atit   +10 more
wiley   +1 more source

Potentiation of drug-induced cytotoxicity by conjugated linoleic acids (CLA) in in vitro models of drug-resistant cancer [PDF]

, 2009
Preclinical studies indicating that conjugated isomers of linoleic acid suppress mitosis, restore apoptosis, induce differentiation and suppress angiogenesis in animal models of cancer formed the rationale for an in vitro investigation of their potential
O'Reilly, Isobel
core  

When Fat Goes Astray: Your Liver and Pancreas Get Into Trouble

Portal Hypertension &Cirrhosis, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) and intrapancreatic fat deposition (IPFD) are both common manifestations of ectopic fat accumulation. Although they share multiple risk factors, they also show notable differences in pathological features, standardization of diagnosis, and research maturity.
Yuying Chen, Li Ding, Shan Zhao, Weihong Wang, Jing Zhong, Qiang Yan   +5 more
wiley   +1 more source

In Vitro Versus in Situ Ruminal Biohydrogenation of Unsaturated Fatty Acids from a Raw or Extruded Mixture of Ground Canola Seed/Canola Meal [PDF]

, 2003
Raw or extruded blends of ground canola seeds and canola meal were used to compare in vitro and in situ lag times and rates of disappearance due to ruminal biohydrogenation of unsaturated fatty acids.
Moncoulon, R., Troegeler-Meynadier, Annabelle, Eynard, P., Bayourthe, Corine, Nicot, M.C., Enjalbert, Francis, Eynard, Philippe, Nicot, Marie-Claude, Bayourthe, C., Troegeler-Meynadier, A., Enjalbert, F.   +10 more
core   +1 more source

High-oleate yeast oil without polyunsaturated fatty acids

Biotechnology for Biofuels, 2018
Background Oleate-enriched triacylglycerides are well-suited for lubricant applications that require high oxidative stability. Fatty acid carbon chain length and degree of desaturation are key determinants of triacylglyceride properties and the ability ...
Vasiliki Tsakraklides, Annapurna Kamineni, Andrew L. Consiglio, Kyle MacEwen, Jonathan Friedlander, Hannah G. Blitzblau, Maureen A. Hamilton, Donald V. Crabtree, Austin Su, Jonathan Afshar, John E. Sullivan, W. Greg LaTouf, Colin R. South, Emily H. Greenhagen, A. Joe Shaw, Elena E. Brevnova   +15 more
doaj   +1 more source

SMILE: Extraction‐free submicron‐resolution mapping of lipid chain length and unsaturation by stimulated Raman imaging

VIEW, EarlyView.
In this work, we develop submicron‐resolution mapping of intracellular lipid elements (SMILE) as an extraction‐free vibrational spectroscopic imaging platform based on hyperspectral stimulated Raman scattering microscopy with a spectral analysis pipeline for pixel‐resolved lipid profiling.
Yihui Zhou, Xiangjie Huang, Xingxin Liu, Ling Zhang, Jie Huang, Jing Zhao, Yongqing Zhang, Jin Zhang, Yanqing Gong, Delong Zhang, Hyeon Jeong Lee   +10 more
wiley   +1 more source

Mechanisms of fatty acid metabolism in tumor metastasis and targeted therapeutic strategies

Discover Oncology
Fatty acid metabolism is a core metabolic pathway regulating tumor metastasis. Through fatty acid uptake and intracellular transport mediated by CD36 and fatty acid-binding proteins (FABPs), fatty acid oxidation (FAO) regulated by carnitine ...
Jiaqi Zhou, Chengwang Guo, Jiaying Li, Xueting Xia, Zhaojuan Bai, Shuping Li, Yongjin Wang, Xiaojun Liu   +7 more
doaj   +1 more source

Ozone‐driven degradation of sex pheromone in Plutella xylostella: Implications for reproductive communication and mating success

Insect Science, EarlyView.
In this study, we examined whether realistic ozone concentrations can interfere with sexual communication in the insect pest Plutella xylostella, the diamondback moth. Ozone exposure caused a degradation of pheromone components, leading to significant changes in blend composition and component ratios.
Francesco Sorrentino, Delia M. Pinto‐Zevallos, Oksana Skaldina, James D. Blande   +3 more
wiley   +1 more source