Results 21 to 30 of about 39,692 (272)

Influence of FADS polymorphisms on tracking of serum glycerophospholipid fatty acid concentrations and percentage composition in children. [PDF]

, 2011
Tracking of fatty acid (FA) contribution to plasma or serum lipids over time was shown in children and adults. However, the potential role of FADS gene variants has not been investigated.
Demmelmair Hans, Berthold Koletzko, Rzehak, P., Claudia Glaser, Peter Rzehak, Joachim Heinrich, Heinrich, Joachim, Glaser, C., Glaser, Claudia, Heinrich, J., LISA study group, Klopp Norman, Demmelmair, Hans, Klopp, N., Rzehak, Peter, Demmelmair, H., Koletzko Berthold, Rzehak Peter, Glaser Claudia, LISAplus Study Group (Wichmann, H.-E. ; Heinrich, J. ; Bolte, G. ; Belcredi, P. ; Jacob, B. ; Schoetzau, A. ; Mosetter, M. ; Schindler, J. ; Höhnke, A.), Hans Demmelmair, null null, Norman Klopp, Heinrich Joachim, Koletzko, Berthold, Klopp, Norman, Koletzko, B.   +26 more
core   +1 more source

Fatty acid desaturase systems of hen liver and their inhibition by cyclopropene fatty acids [PDF]

Lipids, 1969
AbstractHen liver preparations which desaturate stearic acid at the 9,10 position to form oleic acid have been found to desaturate other saturated fatty acids of carbon chain length from 12 to 20 and 22. The 9,10‐monoenoic fatty acid of the same chain length as the substrate fatty acid is the major product formed. Minor amounts of the 10,11‐ and 11, 12‐
A. R. Johnson, A. C. Fogerty, Judith A. Pearson, F. S. Shenstone, Audrey M. Bersten   +4 more
openaire   +3 more sources

Up-regulated delta 9-desaturase gene expression by hypolipidemic peroxisome-proliferating fatty acids results in increased oleic acid content in liver and VLDL: accumulation of a delta 9-desaturated metabolite of tetradecylthioacetic acid

Journal of Lipid Research, 1997
In the liver of rats, monocarboxylic 3-thia fatty acids, tridecylthioacetic acid (C13-S-acetic acid) and tetradecylthioacetic acid (C14-S-acetic acid), increase the mRNA levels of delta 9-desaturase both in a time- and dose-dependent manner.
L Madsen, L Frøyland, H J Grav, R K Berge   +3 more
doaj   +1 more source

Homology modeling and docking studies of a Δ9-fatty acid desaturase from a Cold-tolerant Pseudomonas sp. AMS8 [PDF]

PeerJ, 2018
Membrane-bound fatty acid desaturases perform oxygenated desaturation reactions to insert double bonds within fatty acyl chains in regioselective and stereoselective manners.
Lawal Garba, Mohamad Ariff Mohamad Yussoff, Khairul Bariyyah Abd Halim, Siti Nor Hasmah Ishak, Mohd Shukuri Mohamad Ali, Siti Nurbaya Oslan, Raja Noor Zaliha Raja Abd. Rahman   +6 more
doaj   +2 more sources

Inhibition of Fatty Acyl Desaturase by Cyclopropene Fatty Acids

Journal of Biological Chemistry, 1967
Abstract Comparisons were made of the ratios of the specific activities of stearic acid to oleic acid in adipose tissue and liver triglycerides of rats given methyl stearate-1-14C dissolved in 0.25 ml of corn oil and Sterculia foetida oil. The ratios were about 3 in the corn oil control animals compared to 31 to 43 in adipose tissue and 44 to 246 in ...
P K, Raju, R, Reiser
openaire   +2 more sources

The Generation of Transgenic Mice with Fat1 and Fad2 Genes that have their own Polyunsaturated Fatty Acid Biosynthetic Pathway

Cellular Physiology and Biochemistry, 2013
Background: Microorganisms and higher plants possess their own omega-3 and omega-6 polyunsaturated fatty acid (PUFAs) biosynthetic pathways. The n-6 fatty acid desaturase gene fad-2 codes for the n-6 desaturase enzyme that coverts oleic acid (OA 18:1 n-9)
Yue Chen, Mei Mei, Peng Zhang, Kuiying Ma, Guangqi Song, Xin Ma, Tianchuang Zhao, Bo Tang, Hongsheng Ouyang, Guangpeng Li, Ziyi Li   +10 more
doaj   +1 more source

Activation of Human Stearoyl-Coenzyme A Desaturase 1 Contributes to the Lipogenic Effect of PXR in HepG2 Cells [PDF]

, 2013
The pregnane X receptor (PXR) was previously known as a xenobiotic receptor. Several recent studies suggested that PXR also played an important role in lipid homeostasis but the underlying mechanism remains to be clearly defined.
Wei, Yijuan, Hu, Bingfang, Wen Xie, Xie Wen, Zhai Yonggong, Yonggong Zhai, Huang Min, Bingfang Hu, Hu, B, Xie, W, Jun Zhang, Yijuan Wei, Zhai, Yonggong, Xie, Wen, Min Huang, Zhang Jun, Hu Bingfang, Huang, M, Huang, Min, Wei Yijuan, Zhang, Jun, Zhang, J, Wei, Y, Zhai, Y   +23 more
core   +1 more source

Trans-vaccenate is Δ13-desaturated by FADS3 in rodents

Journal of Lipid Research, 2013
Fatty acid desaturases play critical roles in regulating the biosynthesis of unsaturated fatty acids in all biological kingdoms. As opposed to plants, mammals are so far characterized by the absence of desaturases introducing additional double bonds at ...
Vincent Rioux, Frédérique Pédrono, Hélène Blanchard, Cécile Duby, Nathalie Boulier-Monthéan, Laurence Bernard, Erwan Beauchamp, Daniel Catheline, Philippe Legrand   +8 more
doaj   +1 more source

Identification and analysis of the FAD gene family in walnuts (Juglans regia L.) based on transcriptome data

BMC Genomics, 2020
Background Walnut kernels contain a large amount of unsaturated fatty acids, such as linoleic acid and linolenic acid, which are essential fatty acids for humans and have important effects on growth and health. The main function of fatty acid desaturase (
Kai Liu, Shugang Zhao, Shuang Wang, Hongxia Wang, Zhihua Zhang   +4 more
doaj   +1 more source

Alternation of plasma fatty acids composition and desaturase activities in children with liver steatosis. [PDF]

PLoS ONE, 2017
The aim of this study was to investigate changes in plasma fatty acids proportions and estimated desaturase activities for variable grading of liver steatosis in children.In total, 111 schoolchildren (aged 8-18 years) were included in the analysis from ...
Man-Chin Hua, Hui-Min Su, Tsung-Chieh Yao, Ming-Ling Kuo, Ming-Wei Lai, Ming-Han Tsai, Jing-Long Huang   +6 more
doaj   +1 more source