Results 21 to 30 of about 2,751,456 (226)

Activation of Human Stearoyl-Coenzyme A Desaturase 1 Contributes to the Lipogenic Effect of PXR in HepG2 Cells [PDF]

, 2013
The pregnane X receptor (PXR) was previously known as a xenobiotic receptor. Several recent studies suggested that PXR also played an important role in lipid homeostasis but the underlying mechanism remains to be clearly defined.
Wei, Yijuan, Hu, Bingfang, Wen Xie, Xie Wen, Zhai Yonggong, Yonggong Zhai, Huang Min, Bingfang Hu, Hu, B, Xie, W, Jun Zhang, Yijuan Wei, Zhai, Yonggong, Xie, Wen, Min Huang, Zhang Jun, Hu Bingfang, Huang, M, Huang, Min, Wei Yijuan, Zhang, Jun, Zhang, J, Wei, Y, Zhai, Y   +23 more
core   +2 more sources

Trans-vaccenate is Δ13-desaturated by FADS3 in rodents

Journal of Lipid Research, 2013
Fatty acid desaturases play critical roles in regulating the biosynthesis of unsaturated fatty acids in all biological kingdoms. As opposed to plants, mammals are so far characterized by the absence of desaturases introducing additional double bonds at ...
Vincent Rioux, Frédérique Pédrono, Hélène Blanchard, Cécile Duby, Nathalie Boulier-Monthéan, Laurence Bernard, Erwan Beauchamp, Daniel Catheline, Philippe Legrand   +8 more
doaj   +1 more source

Identification and analysis of the FAD gene family in walnuts (Juglans regia L.) based on transcriptome data

BMC Genomics, 2020
Background Walnut kernels contain a large amount of unsaturated fatty acids, such as linoleic acid and linolenic acid, which are essential fatty acids for humans and have important effects on growth and health. The main function of fatty acid desaturase (
Kai Liu, Shugang Zhao, Shuang Wang, Hongxia Wang, Zhihua Zhang   +4 more
doaj   +1 more source

Alternation of plasma fatty acids composition and desaturase activities in children with liver steatosis. [PDF]

PLoS ONE, 2017
The aim of this study was to investigate changes in plasma fatty acids proportions and estimated desaturase activities for variable grading of liver steatosis in children.In total, 111 schoolchildren (aged 8-18 years) were included in the analysis from ...
Man-Chin Hua, Hui-Min Su, Tsung-Chieh Yao, Ming-Ling Kuo, Ming-Wei Lai, Ming-Han Tsai, Jing-Long Huang   +6 more
doaj   +1 more source

Temperature Acclimation of the Picoalga Ostreococcus tauri Triggers Early Fatty-Acid Variations and Involves a Plastidial ω3-Desaturase

Frontiers in Plant Science, 2021
Alteration of fatty-acid unsaturation is a universal response to temperature changes. Marine microalgae display the largest diversity of polyunsaturated fatty-acid (PUFA) whose content notably varies according to temperature.
Charlotte Degraeve-Guilbault, Nattiwong Pankasem, Maurean Gueirrero, Cécile Lemoigne, Frédéric Domergue, Tomonori Kotajima, Iwane Suzuki, Jérôme Joubès, Florence Corellou   +8 more
doaj   +1 more source

Three-year tracking of fatty acid composition of plasma phospholipids in healthy children [PDF]

, 2007
Objectives: The fatty acid composition of plasma phospholipids reflects the dietary fatty acid intake as well as endogenous turnover. We aimed at investigating the potential tracking of plasma phospholipid fatty acid composition in children that ...
Toschke, Andre Michael, Guerra, Antonio, Koletzko, Berthold, Demmelmair, Hans   +3 more
core   +1 more source

Serum Fatty Acids, Desaturase Activities and Abdominal Obesity - A Population-Based Study of 60-Year Old Men and Women. [PDF]

PLoS ONE, 2017
Abdominal obesity is a key contributor of metabolic disease. Recent trials suggest that dietary fat quality affects abdominal fat content, where palmitic acid and linoleic acid influence abdominal obesity differently, while effects of n-3 polyunsaturated
Zayed D Alsharari, Ulf Risérus, Karin Leander, Per Sjögren, Axel C Carlsson, Max Vikström, Federica Laguzzi, Bruna Gigante, Tommy Cederholm, Ulf De Faire, Mai-Lis Hellénius, Matti Marklund   +11 more
doaj   +1 more source

FADS1 FADS2 gene cluster, PUFA intake and blood lipids in children [PDF]

, 2012
Elevated cholesterol levels in children can be a risk factor for cardiovascular diseases in later life. In adults, it has been shown that blood lipid levels are strongly influenced by polymorphisms in the fatty acid desaturase (FADS) gene cluster in ...
Drogies, Tim, Schaaf, Beate, Krämer, Ursula, Thiery, Joachim, Berg, Andrea von, Buyken, Anette, Berdel, Dietrich, Bauer, Carl-Peter, Lattka, Eva, Standl, Marie, Heinrich, Joachim, Stach, Barbara, Röder, Stefan, Koletzko, Berthold, Herbarth, Olf, Koletzko, Sibylle   +15 more
core   +1 more source

Influence of consumption of high oleic sunflower oil on the biosynthesis of fatty acids in the liver of rats

Journal of Education, Health and Sport, 2022
Background. To determine the effect of consumption of high-oleic sunflower oil on the content and biosynthesis of energy and polyunsaturated (PUFA) fatty acids in rat liver lipids. Methods. Rats received a semi-synthetic fat-free diet in which 5 % or
A. Levitsky, B. Egorov, A. Lapinskaya, I. Selivanskaya, V. Velichko   +4 more
doaj   +1 more source

Isolation of a Delta(5)-fatty acid desaturase gene from Mortierella alpina [PDF]

, 1998
Arachidonic acid (C20:4 Δ5,8,11,14)) is a polyunsaturated fatty acid synthesized by the ?-fatty acid desaturation of di-homo-?-linolenic acid (C20:3 Δ8,11,14)).
Michaelson, L. V., Michaelson, Louise V., Stobart, A. K., Napier, Johnathan A., Stobart, A.Keith, Napier, J. A., Griffiths, G., Griffiths, Gareth, Lazarus, C. M., Lazarus, Colin M.   +9 more
core   +1 more source