Results 31 to 40 of about 2,751,456 (226)

Characterization of an Omega-3 Desaturase From Phytophthora parasitica and Application for Eicosapentaenoic Acid Production in Mortierella alpina

Frontiers in Microbiology, 2018
Omega-3 long-chain polyunsaturated fatty acids (LC-PUFAs) have important therapeutic and nutritional benefits in humans. In the biosynthesis pathways of these LC-PUFAs, omega-3 desaturase plays a critical role.
Xin Tang, Xin Tang, Haiqin Chen, Haiqin Chen, Tiantian Mei, Tiantian Mei, Chengfeng Ge, Chengfeng Ge, Zhennan Gu, Zhennan Gu, Hao Zhang, Hao Zhang, Yong Q. Chen, Yong Q. Chen, Yong Q. Chen, Yong Q. Chen, Wei Chen, Wei Chen, Wei Chen, Wei Chen   +19 more
doaj   +1 more source

Structure and Biosynthesis of Mangotoxin Produced by the Plant Pathogen Pseudomonas syringae

Angewandte Chemie, EarlyView.
The structure of mangotoxin remained elusive for over two decades. Here, mangotoxin was isolated from the native producer, Pseudomonas syringae pv. syringae, and was determined to be an alkyne‐containing dipeptide. Mangotoxin inhibited the growth of multidrug‐resistant human pathogen Klebsiella pneumoniae.
Alexis H. Murray, Sohan Hazra, Ryan W. Mull, Erinn M. O'Neill, Bo Li   +4 more
wiley   +2 more sources

Molecular Cloning and Functional Expression of a Δ9- Fatty Acid Desaturase from an Antarctic Pseudomonas sp. A3.

PLoS ONE, 2016
Fatty acid desaturase enzymes play an essential role in the synthesis of unsaturated fatty acids. Pseudomonas sp. A3 was found to produce a large amount of palmitoleic and oleic acids after incubation at low temperatures. Using polymerase Chain Reaction (
Lawal Garba, Mohd Shukuri Mohamad Ali, Siti Nurbaya Oslan, Raja Noor Zaliha Raja Abd Rahman   +3 more
doaj   +1 more source

Effect of genotype on estimated indexes of fatty acid metabolism in rabbits

World Rabbit Science, 2014
To analyse the effect of rabbit genotype on fatty acid metabolism, 60 weaned rabbits (30 d old, sex ratio 1:1; 20 New Zealand White, 20 Leprino of Viterbo and 20 rabbits of a Local grey population) were reared in bicellular standard cages.
Alessandro Dal Bosco, Cecilia Mugnai, Valentina Roscini, Gisella Paci, Cesare Castellini   +4 more
doaj   +1 more source

Influence of fine process particles enriched with metals and metalloids on Lactuca sativa L. leaf fatty acid composition following air and/or soil-plant field exposure [PDF]

, 2013
We investigate the effect of both foliar and root uptake of a mixture of metal(loid)s on the fatty acid composition of plant leaves. Our objectives are to determine whether both contamination pathways have a similar effect and whether they interact ...
Bessoule, Jean-Jacques, Schreck, Eva, Le Guédard, Marina, Dumat, Camille, Xiong, Tiantian, Foucault, Yann, Austruy, Annabelle, Laplanche, Christophe   +7 more
core   +1 more source

Effect of weight loss on circulating fatty acid profiles in overweight subjects with high visceral fat area: a 12-week randomized controlled trial

Nutrition Journal, 2018
Background Significant associations between visceral fat and alterations in plasma fatty acids have been identified in overweight individuals. However, there are scant data regarding the relationships of the visceral fat area (VFA) with the plasma fatty ...
Young Ju Lee, Ayoung Lee, Hye Jin Yoo, Minjoo Kim, Minkyung Kim, Sun Ha Jee, Dong Yeob Shin, Jong Ho Lee   +7 more
doaj   +1 more source

Identification of amino acid residues that determine the substrate specificity of mammalian membrane-bound front-end fatty acid desaturases

Journal of Lipid Research, 2016
Membrane-bound desaturases are physiologically and industrially important enzymes that are involved in the production of diverse fatty acids such as polyunsaturated fatty acids and their derivatives. Here, we identified amino acid residues that determine
Kenshi Watanabe, Makoto Ohno, Masahiro Taguchi, Seiji Kawamoto, Kazuhisa Ono, Tsunehiro Aki   +5 more
doaj   +1 more source

Relationship between Polyunsaturated Fatty Acid Metabolism and Atherosclerosis

Reviews in Cardiovascular Medicine
Multiple factors cause atherosclerosis, meaning its pathogenesis is complex, and has not been fully elucidated. Polyunsaturated fatty acids are a member of the fatty acid family, which are critical nutrients for mammalian growth and development.
Qiulei Liu, Zhaoxuan Liu, Ding Wu, Sheng Wang   +3 more
doaj   +1 more source

A vertebrate fatty acid desaturase with delta5 and delta6 activities [PDF]

, 2001
Δ5 and Δ6 fatty acid desaturases are critical enzymes in the pathways for the biosynthesis of the polyunsaturated fatty acids (PUFA) arachidonic, eicosapentanoic and docosahexanoic acids.
Sargent, John R, Teale, Alan J, Tocher, Douglas R, Agaba, Morris K, Hastings, Nicola, Leaver, Michael, Dick, James R   +6 more
core   +1 more source

Fatty Acid Profile and Desaturase Activity in Obesity: Roles, Mechanisms, and Clinical Relevance

Metabolites
Background: Obesity is a complex metabolic disease associated with several health complications, including insulin resistance, hypertension, and type 2 diabetes mellitus.
Michalina Banaszak, Ilona Górna, Sławomira Drzymała-Czyż   +2 more
doaj   +1 more source