Results 41 to 50 of about 39,692 (272)

Influence of fine process particles enriched with metals and metalloids on Lactuca sativa L. leaf fatty acid composition following air and/or soil-plant field exposure [PDF]

, 2013
We investigate the effect of both foliar and root uptake of a mixture of metal(loid)s on the fatty acid composition of plant leaves. Our objectives are to determine whether both contamination pathways have a similar effect and whether they interact ...
Bessoule, Jean-Jacques, Schreck, Eva, Le Guédard, Marina, Dumat, Camille, Xiong, Tiantian, Foucault, Yann, Austruy, Annabelle, Laplanche, Christophe   +7 more
core   +1 more source

Effect of weight loss on circulating fatty acid profiles in overweight subjects with high visceral fat area: a 12-week randomized controlled trial

Nutrition Journal, 2018
Background Significant associations between visceral fat and alterations in plasma fatty acids have been identified in overweight individuals. However, there are scant data regarding the relationships of the visceral fat area (VFA) with the plasma fatty ...
Young Ju Lee, Ayoung Lee, Hye Jin Yoo, Minjoo Kim, Minkyung Kim, Sun Ha Jee, Dong Yeob Shin, Jong Ho Lee   +7 more
doaj   +1 more source

A vertebrate fatty acid desaturase with delta5 and delta6 activities [PDF]

, 2001
Δ5 and Δ6 fatty acid desaturases are critical enzymes in the pathways for the biosynthesis of the polyunsaturated fatty acids (PUFA) arachidonic, eicosapentanoic and docosahexanoic acids.
Sargent, John R, Teale, Alan J, Tocher, Douglas R, Agaba, Morris K, Hastings, Nicola, Leaver, Michael, Dick, James R   +6 more
core   +1 more source

Comparative Analysis of Fatty Acid Desaturases in Cyanobacterial Genomes [PDF]

Comparative and Functional Genomics, 2008
Fatty acid desaturases are enzymes that introduce double bonds into the hydrocarbon chains of fatty acids. The fatty acid desaturases from 37 cyanobacterial genomes were identified and classified based upon their conserved histidine-rich motifs and phylogenetic analysis, which help to determine the amounts and distributions of desaturases in ...
Chi, Xiaoyuan, Yang, Qingli, Zhao, Fangqing, Qin, Song, Yang, Yu, Shen, Junjun, Lin, Hanzhi   +6 more
openaire   +2 more sources

Identification of amino acid residues that determine the substrate specificity of mammalian membrane-bound front-end fatty acid desaturases

Journal of Lipid Research, 2016
Membrane-bound desaturases are physiologically and industrially important enzymes that are involved in the production of diverse fatty acids such as polyunsaturated fatty acids and their derivatives. Here, we identified amino acid residues that determine
Kenshi Watanabe, Makoto Ohno, Masahiro Taguchi, Seiji Kawamoto, Kazuhisa Ono, Tsunehiro Aki   +5 more
doaj   +1 more source

Characterization of membrane-bound fatty acid desaturases

General physiology and biophysics, 2013
Membrane-bound desaturases play key role in metabolism of polyunsaturated fatty acids. Characterization of these enzymes and their genes is the first step in basic understanding of their proper functioning in living cells as well as in tailor-made preparation of highly-specific and highly-productive strains of microorganisms interesting for applied ...
Tatiana, Klempova, Daniel, Mihalik, Milan, Certik   +2 more
openaire   +3 more sources

The impact of fatty acid desaturase genotype on fatty acid status and cardiovascular health in adults [PDF]

Proceedings of the Nutrition Society, 2016
The aim of this review was to determine the impact of the fatty acid desaturase (FADS) genotype on plasma and tissue concentrations of the long-chain (LC) n-3 PUFA, including EPA and DHA, which are associated with the risk of several diet-related chronic diseases, including CVD. In addition to dietary intakes, which are low for many individuals, tissue
O'Neill, Colette M., Minihane, Anne-Marie   +1 more
openaire   +5 more sources

Relationship between Polyunsaturated Fatty Acid Metabolism and Atherosclerosis

Reviews in Cardiovascular Medicine
Multiple factors cause atherosclerosis, meaning its pathogenesis is complex, and has not been fully elucidated. Polyunsaturated fatty acids are a member of the fatty acid family, which are critical nutrients for mammalian growth and development.
Qiulei Liu, Zhaoxuan Liu, Ding Wu, Sheng Wang   +3 more
doaj   +1 more source

Mutagenesis of the borage Δ6 fatty acid desaturase

Biochemical Society Transactions, 2000
The consensus sequence of the third histidine box of a range of Δ5, Δ6, Δ8 and sphingolipid desaturases differs from that of the membrane-bound non-fusion Δ12 and Δ15 desaturases in the presence of glutamine instead of histidine. We have used site-directed mutagenesis to determine the importance of glutamine and other residues of the third histidine ...
Sayanova, O. V., Beaudoin, F., Libisch, B., Shewry, P. R., Napier, J. A.   +4 more
openaire   +2 more sources

Alternative transcripts of fatty acid desaturase (FADS) genes [PDF]

Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA), 2010
Alternative splicing is a major mechanism for increasing the range of products encoded by the genome. We recently reported positive identification of the first alternative transcripts (AT) of fatty acid desaturase 3 (FADS3) and FADS2 in fetal and neonatal baboons.
J Thomas, Brenna, Kumar S D, Kothapalli, Woo Jung, Park   +2 more
openaire   +2 more sources