Results 51 to 60 of about 2,715,237 (202)

Influence of Dietary Lipids and Environmental Salinity on the n-3 Long-Chain Polyunsaturated Fatty Acids Biosynthesis Capacity of the Marine Teleost Solea senegalensis

Marine Drugs, 2021
Fish vary in their ability to biosynthesise long-chain polyunsaturated fatty acids (LC-PUFA) depending upon the complement and function of key enzymes commonly known as fatty acyl desaturases and elongases.
Manuel Marrero, Óscar Monroig, Mónica Betancor, Marcelino Herrera, José A. Pérez, Diego Garrido, Ana Galindo, Inmaculada Giráldez, Covadonga Rodríguez   +8 more
doaj   +1 more source

Characterization of Three Types of Elongases from Different Fungi and Site-Directed Mutagenesis

Journal of Fungi
Fatty acid elongases play crucial roles in synthesizing long-chain polyunsaturated fatty acids. Identifying more efficient elongases is essential for enhancing oleaginous microorganisms to produce high yields of target products.
Yuxin Wang, Lulu Chang, Hao Zhang, Yong Q. Chen, Wei Chen, Haiqin Chen   +5 more
doaj   +1 more source

Cannabidiol improves muscular lipid profile by affecting the expression of fatty acid transporters and inhibiting de novo lipogenesis

Scientific Reports, 2023
Obesity is one of the principal public health concerns leading to disturbances in glucose and lipid metabolism, which is a risk factor for several chronic diseases, including insulin resistance, type 2 diabetes mellitus, and cardiovascular diseases.
Patrycja Bielawiec, Sylwia Dziemitko, Karolina Konstantynowicz-Nowicka, Adrian Chabowski, Janusz Dzięcioł, Ewa Harasim-Symbor   +5 more
doaj   +1 more source

In planta analysis of the mode of action of cinmethylin and confirmation of fatty acyl‐ACP thioesterases (FATs) as primary site of action

Pest Management Science, EarlyView.
In planta analysis of the mode of action of cinmethylin and confirmation of fatty acyl‐ACP thioesterases (FATs) as primary site of action. Cinmethylin inhibits FATs, disrupting eukaryotic de novo lipid biosynthesis and causing defects in cell division, elongation and integrity. We confirm FATs as the primary site of action in planta.
Maximillian Pollmeier, Aisha Gerhardt, Janneke Hendriks, Katharina Kaprocki, Alexandra Zimmermann, Sarina Ruehm, Martina Marnet, Maria Stroe, Jorge Alfredo Rojas Biava, Clara Hofmann, Michael Betz, Sascha Schlaefer, Philipp Ternes, Jens Lerchl, Selene Garcia‐Hernandez, Philipp Johnen   +15 more
wiley   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Bioproduction of n-3 polyunsaturated fatty acids by nematode fatty acid desaturases and elongase in Drosophila melanogaster

Transgenic Research, 2023
n-3 polyunsaturated fatty acids (n-3 PUFAs), including α-linolenic acid and eicosapentaenoic acid (EPA), are essential nutrients for vertebrates including humans. Vertebrates are n-3 PUFA-auxotrophic; hence, dietary intake of n-3 PUFAs is required for their normal physiology and development.
Mai, Sato, Ryoma, Ota, Satoru, Kobayashi, Kimiko, Yamakawa-Kobayashi, Takeshi, Miura, Atsushi, Ido, Yuya, Ohhara   +6 more
openaire   +2 more sources

Novel Fatty Acid Desaturases And Elongases And Uses Thereof (Patent EP 2454278 A1)

, 2012
The invention provides isolated nucleic acid molecules which encode novel fatty acid desaturases and elongases from the organism Emiliana huxleyi. The invention also provides recombinant expression vectors containing desaturase or elongase nucleic acid ...
Sayanova, O. V., Napier, J. A., Bauer, J.   +2 more
core   +2 more sources

DHA intake interacts with ELOVL2 and ELOVL5 genetic variants to influence polyunsaturated fatty acids in human milk

Journal of Lipid Research, 2019
Endogenous synthesis of PUFAs is mediated by genes controlling fatty acid elongases 2 and 5 (ELOVL2 and ELOVL5) and by exogenous DHA intake. Associations between elongases and PUFA levels probably involve genetic variants of ELOVL and changes in DHA ...
Yixia Wu霞吴义, Yan Wang 烟王, Huimin Tian敏田慧, Tong Lu逯通, Miao Yu苗于, Wenhui Xu慧徐文, Guoliang Liu良刘国, Lin Xie林谢   +7 more
doaj   +1 more source

Altered desaturation and elongation of fatty acids in hormone-sensitive lipase null mice. [PDF]

PLoS ONE, 2011
BACKGROUND: Hormone-sensitive lipase (HSL) is expressed predominantly in adipose tissue, where it plays an important role in catecholamine-stimulated hydrolysis of stored lipids, thus mobilizing fatty acids.
Céline Fernandez, Kai Schuhmann, Ronny Herzog, Barbara Fielding, Keith Frayn, Andrej Shevchenko, Peter James, Cecilia Holm, Kristoffer Ström   +8 more
doaj   +1 more source

Generating Pennycress (Thlaspi arvense) Seed Triacylglycerols and Acetyl-Triacylglycerols Containing Medium-Chain Fatty Acids

Frontiers in Energy Research, 2021
Thlaspi arvense L. (pennycress) is a cold-tolerant Brassicaceae that produces large amounts of seeds rich in triacylglycerols and protein, making it an attractive target for domestication into an offseason oilseed cash cover crop.
Maliheh Esfahanian, Tara J. Nazarenus, Meghan M. Freund, Gary McIntosh, Winthrop B. Phippen, Mary E. Phippen, Timothy P. Durrett, Edgar B. Cahoon, John C. Sedbrook   +8 more
doaj   +1 more source