Results 71 to 80 of about 633,143 (229)

DHA intake interacts with ELOVL2 and ELOVL5 genetic variants to influence polyunsaturated fatty acids in human milk

Journal of Lipid Research, 2019
Endogenous synthesis of PUFAs is mediated by genes controlling fatty acid elongases 2 and 5 (ELOVL2 and ELOVL5) and by exogenous DHA intake. Associations between elongases and PUFA levels probably involve genetic variants of ELOVL and changes in DHA ...
Yixia Wu霞吴义, Yan Wang 烟王, Huimin Tian敏田慧, Tong Lu逯通, Miao Yu苗于, Wenhui Xu慧徐文, Guoliang Liu良刘国, Lin Xie林谢   +7 more
doaj   +1 more source

Plasma and erythrocyte fatty acid patterns in patients with recurrent depression: a matched case-control study. [PDF]

PLoS ONE, 2010
BackgroundThe polyunsaturated fatty acid (PUFA) composition of (nerve) cell membranes may be involved in the pathophysiology of depression. Studies so far, focussed mainly on omega-3 and omega-6 PUFAs.
Johanna Assies, François Pouwer, Anja Lok, Roel J T Mocking, Claudi L H Bockting, Ieke Visser, Nico G G M Abeling, Marinus Duran, Aart H Schene   +8 more
doaj   +1 more source

Zinc Deficiency, Plasma Fatty Acid Profile and Desaturase Activities in Hemodialysis Patients: Is Supplementation Necessary?

Frontiers in Nutrition, 2021
Background: Desaturation and elongation are critical processes in endogenous metabolic fatty acid pathways. Zinc (Zn) is a cofactor for desaturases and elongases enzymes.
Marija Takić, Milica Zeković, B. Terzić, A. Stojsavljević, M. Mijuskovic, S. Radjen, D. Ristić-Medić   +6 more
semanticscholar   +1 more source

Novel Fatty Acid Desaturases And Elongases And Uses Thereof (Patent WO 2011/006948 A1) [PDF]

, 2011
The invention provides isolated nucleic acid molecules which encode novel fatty acid desaturases and elongases from the organism Emiliana huxleyi. The invention also provides recombinant expression vectors containing desaturase or elongase nucleic acid ...
Sayanova, O. V., Napier, J. A., Bauer, J.   +2 more
core  

Remodeling of retinal fatty acids in an animal model of diabetes: A decrease in long-chain polyunsaturated fatty acids is associated with a decrease in fatty acid elongases Elovl2 and Elovl4 [PDF]

, 2010
OBJECTIVE: The results of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications cohort study revealed a strong association between dyslipidemia and the development of diabetic retinopathy.
Lydic, TA, Wang, Y, Sochacki, A, Renis, RL, Reid, GE, Opreanu, M, Tikhonenko, M, Busik, JV, Chen, W, McSorley, KM, Kern, T, Jump, DB   +11 more
core   +1 more source

Continental accumulation of fads2 copy numbers allows sticklebacks to thrive across a diversity of nutritional landscapes

Oikos, EarlyView.
Nutrients, including vital organic compounds, vary in availability across ecosystems, with the potential to act as a source of selection for traits that increase nutrient acquisition and biosynthesis. Compared to freshwaters, marine ecosystems are richer in the omega‐3 long‐chain polyunsaturated fatty acid (n‐3 LC‐PUFA) docosahexaenoic acid (DHA ...
Cornelia W. Twining, Cameron M. Hudson, Jernej Bravničar, Antonella Carosi, Gaël P. J. Denys, Philine G. D. Feulner, Žiga Fišer, Hanna Rosinger, Verena Saladin, Linda Zanella, Davor Zanella, Catherine L. Peichel, Blake Matthews   +12 more
wiley   +1 more source

Soluble Fiber Inulin Consumption Limits Alterations of the Gut Microbiota and Hepatic Fatty Acid Metabolism Caused by High-Fat Diet

Nutrients, 2021
Diet shapes the gut microbiota which impacts hepatic lipid metabolism. Modifications in liver fat content are associated with metabolic disorders.
Mayssa Albouery, A. Bretin, B. Buteau, S. Grégoire, L. Martine, S. Gambert, A. Bron, N. Acar, B. Chassaing, M. Bringer   +9 more
semanticscholar   +1 more source

SMILE: Extraction‐free submicron‐resolution mapping of lipid chain length and unsaturation by stimulated Raman imaging

VIEW, EarlyView.
In this work, we develop submicron‐resolution mapping of intracellular lipid elements (SMILE) as an extraction‐free vibrational spectroscopic imaging platform based on hyperspectral stimulated Raman scattering microscopy with a spectral analysis pipeline for pixel‐resolved lipid profiling.
Yihui Zhou, Xiangjie Huang, Xingxin Liu, Ling Zhang, Jie Huang, Jing Zhao, Yongqing Zhang, Jin Zhang, Yanqing Gong, Delong Zhang, Hyeon Jeong Lee   +10 more
wiley   +1 more source

Molecular Characterization, Tissue Distribution and Differential Nutritional Regulation of Three n-3 LC-PUFA Biosynthesis-Related Genes in Hybrid Grouper (Epinephelus fuscoguttatus ♀ × Epinephelus lanceolatus ♂)

Animals, 2022
Elongases of very long-chain fatty acids (Elovls) and fatty acid desaturases (Fads) are crucial enzymes involved in the biosynthesis of long-chain polyunsaturated fatty acids (LC-PUFAs). In this paper, we report the molecular cloning and characterization
Qingjun Wu, Zhi Zheng, Chuijin Wang, Yao Wang, Yuejia Sun, Yujie Gao   +5 more
doaj   +1 more source

Essential fatty acid metabolism and requirements of the cleaner fish, ballan wrasse Labrus bergylta: Defining pathways of long-chain polyunsaturated fatty acid biosynthesis [PDF]

, 2018
Ballan wrasse (Labrus bergylta) is an effective counter-measure against sea lice used by Atlantic salmon farmers, proving to be more effective and economical than drugs or chemical treatments alone.
Angela Oboh, Tocher, Douglas R, Monroig, Oscar, Yevzelman, Simon, Oboh, Angela, Simon Yevzelman, Naoki Kabeya, Oscar Monroig, Kabeya, Naoki, Douglas R. Tocher   +9 more
core   +1 more source