Results 81 to 90 of about 2,715,237 (202)

Egg Peptides From American Shad Extend Lifespan and Healthspan in Caenorhabditis elegans via Lipid Metabolism Remodeling and Antioxidant Defense

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
A novel shad egg peptide (EP) significantly extends Caenorhabditis elegans lifespan through a dual antiaging mechanism. EP systematically remodels lipid metabolism to reinforce cell membranes by promoting beneficial fatty acid biosynthesis and suppressing degradation. Simultaneously, its potent antioxidant activity alleviates oxidative damage, shifting
Jia Du, Qinghua Liu, Zhongxiao Wan, Naomi Sudo, Yanyang Xu   +4 more
wiley   +1 more source

Biochemical characterization of the very long-chain fatty acid elongase ELOVL7 [PDF]

FEBS Letters, 2011
Very long-chain fatty acids (VLCFAs) have a variety of physiological functions and are related to numerous disorders. The key step of VLCFA elongation is catalyzed by members of the elongase family, ELOVLs. Mammals have seven ELOVLs (ELOVL1-7), yet none of them has been purified and analyzed.
Naganuma, Tatsuro, Sato, Yuichiro, Sassa, Takayuki, Ohno, Yusuke, Kihara, Akio   +4 more
openaire   +4 more sources

Effect of animal and industrial trans fatty acids on HDL and LDL cholesterol levels in humans - a quantitative review [PDF]

, 2010
Background: Trans fatty acids are produced either by industrial hydrogenation or by biohydrogenation in the rumens of cows and sheep. Industrial trans fatty acids lower HDL cholesterol, raise LDL cholesterol, and increase the risk of coronary heart ...
Wanders Anne J., Brouwer, I.A.; id_orcid, Martijn B. Katan, Katan Martijn B., Martijn B Katan, Ingeborg A Brouwer, Anne J. Wanders, Brouwer, I.A., Katan, M.B.; id_orcid, Katan, M.B., Anne J Wanders, Wanders, A.J., Ingeborg A. Brouwer, Brouwer Ingeborg A.   +13 more
core   +4 more sources

Dietary Intervention With Lutein, Docosahexaenoic Acid, and Choline During Early Development Improves Recognition Memory in Young Adult Females in an Experimental Model

Molecular Nutrition &Food Research, Volume 70, Issue 17, 15 September 2026.
Our study investigates the effects of perinatal supplementation with lutein, DHA, and choline in a controlled rat model. The results show: (1) strictly sex‐specific effects exclusively observed in female rats, (2) lutein‐dependent and synergistic effects, (3) enhancement of long‐term recognition memory, and (4) no effects on locomotor activity, anxiety‐
Leon Saschin, Gregor Fink, Maria Wohlfarth, Jonas Hauser, Jian Yan, Dirk Wiedermann, Mathias Hoehn, Jochen Wilhelm, Lea Quell, Elisabeth Sous, Jenny Voggel, Jörg Dötsch, Eva Nüsken, Kai‐Dietrich Nüsken   +13 more
wiley   +1 more source

High-throughput analysis of total plasma fatty acid composition with direct in situ transesterification. [PDF]

, 2010
Plasma fatty acid (FA) composition reflects dietary intake and endogenous turnover and is associated with health outcomes on a short and long term basis. The total plasma FA pool represents the composition of all FA containing lipid fractions.
Hans Demmelmair, Demmelmair Hans, Koletzko Berthold, Glaser, Claudia, Berthold Koletzko, Koletzko, Berthold, Glaser Claudia, Demmelmair, Hans, Claudia Glaser   +8 more
core   +2 more sources

Systems‐Level Plant Responses Reveal Pseudomonas‐Mediated Growth Promotion in Brachypodium Under Nitrogen Limitation

Plant, Cell &Environment, Volume 49, Issue 9, Page 6396-6412, September 2026.
ABSTRACT Plant growth–promoting bacteria can enhance plant performance under nutrient limitation, yet the underlying plant molecular responses remain incompletely resolved. We investigated growth promotion by Pseudomonas koreensis in Brachypodium distachyon under contrasting nitrogen (N) regimes using time‐resolved phenotyping, elemental analysis ...
Stefan Sanow, Melissa Mantz, Holger Wissel, Atul Bhatnagar, Elena Sturm, Jana M. Kelm, Robert Walker, Andreas Lücke, Gabriel Schaaf, Pitter F. Huesgen, Ute Roessner, Michelle Watt, Borjana Arsova   +12 more
wiley   +1 more source

FADS Gene Cluster Polymorphisms: Important Modulators of Fatty Acid Levels and Their Impact on Atopic Diseases [PDF]

, 2009
Long-chain polyunsaturated fatty acids (LC-PUFAs) play an important role in several physiological processes and their concentration in phospholipids has been associated with several complex diseases, such as atopic disease.
Lattka, E., Lattka, Eva, Heinrich, Joachim, Illig, T., Koletzko, Berthold, Heinrich, J., Illig, Thomas, Koletzko, B.   +7 more
core   +1 more source

Compensatory induction of Fads1 gene expression in heterozygous Fads2-null mice and by diet with a high n-6/n-3 PUFA ratio[S]

Journal of Lipid Research, 2016
In mammals, because they share a single synthetic pathway, n-6/n-3 ratios of dietary PUFAs impact tissue arachidonic acid (ARA) and DHA content. Likewise, SNPs in the human fatty acid desaturase (FADS) gene cluster impact tissue ARA and DHA.
Hang Su, Dan Zhou, Yuan-Xiang Pan, Xingguo Wang, Manabu T. Nakamura   +4 more
doaj   +1 more source

Stage‐Specific H3K14 and H3K23 Succinylation Orchestrates Insect Metamorphosis and Oogenesis

Advanced Science, Volume 13, Issue 43, 3 August 2026.
Stage‐specific succinylation of histone H3 at lysine 14 and 23 differentially controls insect metamorphosis and oogenesis through distinct GPCR‐PKC signaling cascades, revealing an evolutionarily conserved epigenetic mechanism that coordinates key life‐history traits.
Yu‐Pu Jing, Lunjie Li, Libin Yang, Lin‐Jie Zhang, Qiang Yan, Ci Zhang, Zanrong Wen, Guangze Yu, Qian Li, Shutang Zhou   +9 more
wiley   +1 more source

Fatty acid reductases (FAR): Insights into the biosynthesis of fatty alcohols in plants and bacteria [PDF]

, 2011
Primary fatty alcohols are present in all phyla, where they serve various unique biological functions, either in structural materials or biochemical compounds.
Doan, Thuy
core   +1 more source