Results 81 to 90 of about 633,143 (229)

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Roles of vitamin A in the regulation of fatty acid synthesis

World Journal of Clinical Cases, 2021
Dietary macronutrients and micronutrients play important roles in human health. On the other hand, the excessive energy derived from food is stored in the form of triacylglycerol.
Fu-Chen Yang, Feng Xu, Tiannan Wang, Guoxun Chen   +3 more
semanticscholar   +1 more source

Novel Fatty Acid Desaturases And Elongases And Uses Thereof (Patent US 2017/0067070 A1) [PDF]

, 2017
The invention provides isolated nucleic acid molecules which encode novel fatty acid desaturases and elongases from the organism Emiliana huxleyi. The invention also provides recombinant expression vectors containing desaturase or elongase nucleic acid ...
Sayanova, O. V., Napier, J. A., Bauer, J.   +2 more
core  

The malate–aspartate shuttle supports thermogenic lipid mobilization in brown adipocytes

The FEBS Journal, EarlyView.
Brown fat cells burn lipids within their mitochondria to generate heat. This process involves two energy “shuttles,” one of which is naturally blocked during heat production. We found that the second shuttle (MASh) is not required to generate heat. However, when MASh is disabled, the fatty acids meant for fuel are instead converted back into stored fat.
Michaela Veliova, Caroline M. Ferreira, Katrina P. Montales, Francisco Villalobos, Alexandra J. Brownstein, Rebeca Acín‐Pérez, Gabrielly S. Ferreira, Anthony E. Jones, Linsey Stiles, Ajit S. Divakaruni, Marc Liesa, Orian S. Shirihai, Marcus F. Oliveira   +12 more
wiley   +1 more source

Associations Among Fatty Acids, Desaturase and Elongase, and Insulin Resistance in Children

Journal of the American College of Nutrition, 2017
Fatty acid profiles and desaturase (SCD-16, SCD018, D5D, D6D) and elongase (ELOVL6) enzyme activity have been associated with adiposity and metabolic disease. While this has been studied in adults, few studies have included children. The objective of this study was to evaluate these markers in children and identify relationships with markers of ...
Lori M. Beccarelli, Rachel Erin Scherr, John W. Newman, Alison G. Borkowska, Ira J. Gray, Jessica D. Linnell, Carl L. Keen, Heather M. Young   +7 more
openaire   +4 more sources

Preimaginal development of Aedes aegypti L. (Diptera: Culicidae) in brackish water gives rise to adult mosquitoes with thicker cuticles and greater insecticide resistance

Medical and Veterinary Entomology, EarlyView.
The principal arboviral vector Aedes aegypti can develop in coastal brackish water field habitats (0.5–15 g/L salt) with larvae possessing thicker cuticles and greater resistance to the larvicide Temephos. Females emerging from brackish water‐developing preimaginal stages are now shown to have thicker and remodelled leg and abdominal cuticles and ...
Kokila Sivabalakrishnan, Andrew Hemphill, S. H. P. Parakrama Karunaratne, Arunasalam Naguleswaran, Isabel Roditi, Sinnathamby N. Surendran, Ranjan Ramasamy   +6 more
wiley   +1 more source

Biosynthesis of Triacylglycerols (TAGs) in plants and algae

International Journal of Plant Biology, 2011
Triacylglycerols (TAGs), which consist of three fatty acids bound to a glycerol backbone, are major storage lipids that accumulate in developing seeds, flower petals, pollen grains, and fruits of innumerous plant species.
Alexandro Cagliari, Rogerio Margis, Felipe dos Santos Maraschin, Andreia Carina Turchetto-Zolet, Guilherme Loss, Marcia Margis-Pinheiro   +5 more
doaj   +1 more source

Novel insights into seed fatty acid synthesis and modification pathways from genetic diversity and quantitative trait loci analysis of the Brassica C genome [PDF]

, 2007
Natural genetic variation in fatty acid synthesis and modification pathways determine the composition of vegetable oils, which are major components of human diet and renewable products.
Larson, Tony R., Larson, T R, Larson, T. R., Lynn, J R, Graham, Ian A., Barker, G C, Lynn, J. R., King, G J, Graham, I. A., Barker, G. C., King, G. J., King, Graham J., Graham, I A, Barker, Guy C., Lynn, James R.   +14 more
core   +1 more source

The algal homolog of the plant CER1 and CER3 proteins is a bifunctional hydrocarbon‐forming enzyme

New Phytologist, EarlyView.
Schematic representation of the proposed reactions carried out by a CER1/3 protein from green algae. CoA, coenzyme A; CTD, C‐terminal domain; Cys, catalytic cysteine of C‐terminal domain; His, catalytic histidines of N‐terminal domain; NTD, N‐terminal domain.
Ángel Baca‐Porcel, Bertrand Légeret, Alexandre Six, Mallaury Cabanel, Mathilde Le Cossec, Arthur Guegano, Damien Sorigué, Yonghua Li‐Beisson, Florian Veillet, Fred Beisson   +9 more
wiley   +1 more source

Site‐directed mutagenesis of a fatty acid elongase ELO‐like condensing enzyme [PDF]

FEBS Letters, 2013
The condensation step of fatty acid elongation is the addition of a C2 unit from malonyl‐CoA to an acyl primer catalyzed by one of two families of enzymes, the 3‐ketoacyl‐CoA synthases and the ELO‐like condensing enzymes. 3‐Ketoacyl‐CoA synthases use a Claisen‐like reaction mechanism while the mechanism of the ELO‐catalyzed condensation reaction is ...
Hernandez-Buquer, Selene, Blacklock, Brenda J.   +1 more
openaire   +2 more sources