Frequency and distribution of FCN2 and FCN3 functional variants among MBL2 genotypes [PDF]
Immunogenetics, 2016 To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files.
Helga Bjarnadóttir
exaly +6 more sources
Association of FCN2 polymorphisms and Ficolin-2 levels with dengue fever in Vietnamese patients [PDF]
International Journal of Infectious Diseases, 2020 Background and objective: The human ficolin-2, encoded by FCN2, recognizes pathogen-associated acetylated residues on their cell surfaces and activates the lectin complement cascade. This study aimed to investigate the contribution of human ficolin-2 and
Hoang Van Tong +2 more
exaly +6 more sources
Polymorphisms of the FCN2 Gene 3’UTR Region and Their Clinical Associations in Preterm Newborns [PDF]
Frontiers in Immunology, 2021 Ficolin-2 is regarded as an important innate immunity factor endowed with both lectin (carbohydrate recognition) qualities and ability to induce complement activation.
Anna S Swierzko +2 more
exaly +6 more sources
Association of L-Ficolin Levels and FCN2 Genotypes with Chronic Chagas Disease
PLoS ONE, 2013 BackgroundL-ficolin (encoded by FCN2) binds to acetylated sugar moieties of many pathogens, including Trypanosoma cruzi, promoting their phagocytosis and lysis by the complement system.MethodsWe investigated L-ficolin levels in 160 T.
Angelica Beate Winter Boldt +1 more
exaly +6 more sources
Association of Ficolin-2 Serum Levels and FCN2 Genetic Variants with Indian Visceral Leishmaniasis
PLoS ONE, 2015 BackgroundVisceral leishmaniasis (VL), one of the neglected tropical diseases, is endemic in the Indian subcontinent. Ficolins are circulating serum proteins of the lectin complement system and involved in innate immunity.MethodsWe have estimated ficolin-
Anshuman Mishra +2 more
exaly +6 more sources
PLoS ONE, 2015 Ficolin-2 (FCN2) is an innate immune pattern recognition molecule that can activate the complement pathway, opsonophagocytosis, and elimination of the pathogens.
Chong Wang, Ji-Cheng Li, Feng Jiang
exaly +6 more sources
Ficolin-2 Levels and FCN2 Haplotypes Influence Hepatitis B Infection Outcome in Vietnamese Patients
PLoS ONE, 2011 Human Ficolin-2 (L-ficolins) encoded by FCN2 gene is a soluble serum protein that plays an important role in innate immunity and is mainly expressed in the liver.
Hoang Van Tong +2 more
exaly +7 more sources
Selected SNPs of FCN2 Associated with Chronic Tonsillitis in the Polish Adult Population. [PDF]
Genes (Basel), 2023 Chronic tonsillitis is a problem related to bacterial and viral infections. Ficolins play a key role in the defence against various pathogens. In the present study, we investigated the associations between the selected single nucleotide polymorphisms ...
Gaździcka J +8 more
europepmc +5 more sources
International Journal of Molecular Sciences, 2022 Single nucleotide polymorphisms (SNPs) localised to the promoter region of the FCN2 gene are known to influence the concentration of ficolin-2 in human serum and therefore potentially have clinical associations.
Anna S Swierzko +2 more
exaly +4 more sources
Variants of IL6, IL10, FCN2, RNASE3, IL12B and IL17B loci are associated with Schistosoma mansoni worm burden in the Albert Nile region of Uganda. [PDF]
PLoS Neglected Tropical Diseases, 2023 BackgroundIndividuals genetically susceptible to high schistosomiasis worm burden may contribute disproportionately to transmission and could be prioritized for control.
Oscar Asanya Nyangiri +16 more
doaj +3 more sources