Results 21 to 30 of about 2,051 (177)

Species differences in opsonization and phagocyte recognition of preclinical poly-2-alkyl-2-oxazoline-coated nanoparticles [PDF]

Nature Communications
Poly(ethylene glycol) (PEG) is widely used in nanomedicine design, but emerging PEG immunogenicity in the general population is of therapeutic concern.
R. Tavano, L. Morillas-Becerril, A. Geffner-Smith, G. Ronzani, R. Gervasutti, G. Arrigoni, I. Battisti, M. Morbidelli, P. Polverino de Laureto, L. Palazzi, A. Natale, E. Schiavon, P. Coin, E. M. Benetti, M. Romio, F. Corzana, E. Jiménez-Moreno, M. Sturlese, G. Bolcato, S. Moro, S. M. Moghimi, F. Mancin, E. Papini   +22 more
doaj   +2 more sources

Extremes of l-ficolin concentration in children with recurrent infections are associated with single nucleotide polymorphisms in the FCN2 gene

Clinical and Experimental Immunology, 2007
Summary l-ficolin (also called ficolin-2, P35 or hucolin) is a soluble pattern recognition molecule of suspected importance in anti-microbial immunity. It activates the lectin pathway of complement and acts as an opsonin. l-ficolin, encoded by the FCN2 gene, recognizes microbial polysaccharides and glycoconjugates rich in GlcNAc or ...
Maciej Cedzynski
exaly   +5 more sources

Inflammatory proteins associated with Alzheimer’s disease reduced by a GLP1 receptor agonist: a post hoc analysis of the EXSCEL randomized placebo controlled trial [PDF]

Alzheimer’s Research & Therapy
Background Glucagon-like peptide-1 receptor agonists are a viable option for the prevention of Alzheimer’s disease (AD) but the mechanisms of this potential disease modifying action are unclear.
Ivan Koychev, Graham Reid, Maggie Nguyen, Robert J. Mentz, Dan Joyce, Svati H. Shah, Rury R. Holman   +6 more
doaj   +2 more sources

Identification of Cardiometabolic Protein Biomarkers for Acute Myocardial Infarction Using Olink Proteomics [PDF]

Journal of Inflammation Research
Xin Tan,1,2 Xiangyu Wang,1,2 Shuai Xu,1,2 Yiyao Zeng,1,2 Ge Zhang,3 Anchen Xu,1,2 Yufeng Jiang,1,2 Hezi Jiang,1,2 Yahui Song,4 Jili Fan,5 Yangjun Fu,6 Xiaohong Bo,5 Huimin Fan,1,4 Yafeng Zhou1,2 1Department of Cardiology, the Fourth Affiliated Hospital ...
Tan X, Wang X, Xu S, Zeng Y, Zhang G, Xu A, Jiang Y, Jiang H, Song Y, Fan J, Fu Y, Bo X, Fan H, Zhou Y   +13 more
doaj   +2 more sources

Association of ficolin-2 (FCN2) functional polymorphisms and protein levels with rheumatic fever and rheumatic heart disease: relationship with cardiac function

Archives of Medical Science – Atherosclerotic Diseases, 2018
Introduction A role for ficolin (FCN) 2 gene polymorphisms in the pathogenesis of recurrent severe streptococcal infections and rheumatic carditis has been suggested.
Manal F. Elshamaa, H. Hamza, Naglaa Abd El Rahman, S. Emam, E. Elghoroury, T. Farid, A. Z. Zaher, Mona H. Ibrahim, S. Kamel, D. A. El-Aziz   +9 more
semanticscholar   +3 more sources

Evaluation of five global AI models for predicting weather in Eastern Asia and Western Pacific

npj Climate and Atmospheric Science
Recent development of artificial intelligence (AI) technology has resulted in the fruition of machine learning-based weather prediction (MLWP) systems.
Cheng-Chin Liu, Kathryn Hsu, Melinda S. Peng, Der-Song Chen, Pao-Liang Chang, Ling-Feng Hsiao, Chin-Tzu Fong, Jing-Shan Hong, Chia-Ping Cheng, Kuo-Chen Lu, Chia-Rong Chen, Hung-Chi Kuo   +11 more
doaj   +2 more sources

FCN2 wt Allele [PDF]

Definitions, 2020

semanticscholar   +2 more sources

Identifying the NEAT1/miR-26b-5p/S100A2 axis as a regulator in Parkinson's disease based on the ferroptosis-related genes. [PDF]

PLoS ONE
ObjectivesParkinson's disease (PD) is a complex neurodegenerative disease with unclear pathogenesis. Some recent studies have shown that there is a close relationship between PD and ferroptosis.
Taole Li, Jifeng Guo
doaj   +2 more sources

Genetic insight into putative causes of xanthelasma palpebrarum: a Mendelian randomization study [PDF]

Frontiers in Immunology
Xanthelasma palpebrarum (XP) is the most common form of cutaneous xanthoma, with a prevalence of 1.1%~4.4% in the population. However, the cause of XP remains largely unknown.
Wenting Hu, Yaozhong Liu, Cuihong Lian, Haocheng Lu   +3 more
doaj   +2 more sources

Complement pathway dysregulation and astrocyte alterations in Down syndrome: evidence from postmortem brain tissue and iPSC-derived astrocytes [PDF]

Acta Neuropathologica Communications
Background Down syndrome (DS), or trisomy 21 (T21), resulting from an extra copy of chromosome 21, occurs in 1 in 700–1,000 live births. Neuroinflammation is increasingly recognized as a critical contributor to DS neuropathology, although its underlying ...
André Luíz Teles e Silva, Pedro Henrique Prado de Oliveira, Bruno Yukio Yokota-Moreno, Jéssica da Silva Fausto, Jonatan Peña Avila, Helder I. Nakaya, Andréa Laurato Sertié, Bruna Lancia Zampieri   +7 more
doaj   +2 more sources