Multiple Infectious Complications in a Severely Injured Patient with Single Nucleotide Polymorphisms in Important Innate Immune Response Genes [PDF]
, 2015 Trauma is a major public health problem worldwide. Infectious complications, sepsis, and multiple organ dysfunction syndrome (MODS) remain important causes for morbidity and mortality in patients who survive the initial trauma.
Bronkhorst, M.W.G.A. (Maarten) +2 more
core +2 more sources
Frontiers in Immunology, 2020 A prospective study of 312 patients [194 with multiple myeloma (MM) and 118 with lymphomas (LYMPH)] receiving high-dose chemotherapy and autologous hematopoietic stem cell transplantation (auto-HSCT) was conducted.
Anna S. Świerzko +21 more
doaj +1 more source
PLoS ONE, 2012 BackgroundFicolin-2 coded by FCN2 gene is a soluble serum protein that plays an important role in innate immunity. In this study, we analyzed five functional polymorphisms of the FCN2 gene for their possible association with cutaneous leishmaniasis ...
Amal Assaf +6 more
doaj +1 more source
Rational Conformal Field Theories and Complex Multiplication [PDF]
, 2002 We study the geometric interpretation of two dimensional rational conformal field theories, corresponding to sigma models on Calabi-Yau manifolds. We perform a detailed study of RCFT's corresponding to T^2 target and identify the Cardy branes with ...
Gukov, Sergei, Vafa, Cumrun
core +2 more sources
Polymorphism in ficolin-1 (FCN1) gene is associated with an earlier onset of type 1 diabetes mellitus in children and adolescents from northeast Brazil [PDF]
, 2016 10siFicolins are innate immune proteins able to activate the complement system by the lectin pathway. Single nucleotide polymorphisms (SNPs) of FCN1 and FCN2 genes, encoding for ficolin 1 and 2, have been related to the susceptibility to infectious and ...
GLAUCIA ALYNE NUNES DE LACERDA +9 more
core +1 more source
Extracellular vesicle proteomics uncovers energy metabolism, complement system, and endoplasmic reticulum stress response dysregulation postexercise in males with myalgic encephalomyelitis/chronic fatigue syndrome. [PDF]
Clin Transl MedEVs were isolated from plasma of ME/CFS patients and healthy controls at baseline, and 15 min and 24 h postexercise. Untargeted proteomics revealed dysregulation in energy metabolism, the complement system, and the endoplasmic reticulum stress response. Changes in EV protein levels postexercise are associated with post‐exertional malaise.
Glass KA +3 more
europepmc +2 more sources
FunctionalObjects.h: Using Symbolic Syntax in C++ Programs [PDF]
, 2000 functionalObjects.h allows the C++ programmer performing common mathematical calculations to use a more symbolic syntax rather than an algorithmic syntax.
Nolty, R.
core +2 more sources
Frontiers in Oncology, 2021 Hepatocellular carcinoma (HCC) is the most common malignant tumor of the liver, with high morbidity and mortality, yet its molecular mechanisms of tumorigenesis are still unclear. In this study, gene expression profile of GSE62232 was downloaded from the
Sumei Wang +23 more
doaj +1 more source
Effects of sequence variations in innate immune response genes on infectious outcome in trauma patients: A comprehensive review [PDF]
, 2015 Infectious complications, sepsis, and multiple organ dysfunction syndrome (MODS) remain important causes for morbidity and mortality in patients who survive the initial trauma.
Bronkhorst, M.W.G.A. (Maarten) +2 more
core +1 more source
The Lectin Pathway of Complement Activation Is a Critical Component of the Innate Immune Response to Pneumococcal Infection [PDF]
, 2012 The complement system plays a key role in host defense against pneumococcal infection. Three different pathways, the classical, alternative and lectin pathways, mediate complement activation.
Ali, Youssif M. +15 more
core +4 more sources