Results 91 to 100 of about 3,812 (172)

Integrated transcriptomic and proteomic analyses reveal the mechanism of easy acceptance of artificial pelleted diets during food habit domestication in Largemouth bass (Micropterus salmoides)

Scientific Reports, 2023
Acceptance of artificial pelleted diets contributes to increasing the cultured areas and output of carnivorous fish. However, the mechanism of acceptance of artificial pelleted diets remains largely unknown.
Jinxing Du, Jiaqi Shao, Shengjie Li, Tao Zhu, Hongmei Song, Caixia Lei, Meng Zhang, Yingkun Cen   +7 more
doaj   +1 more source

Regulation of dolichol-linked glycosylation [PDF]

, 2018
In the majority of congenital disorders of glycosylation, the assembly of the glycan precursor GlcNAc2Man9Glc3 on the polyprenol carrier dolichyl-pyrophosphate is compromised.
Welti, Michael
core  

Distinct roles and molecular mechanisms of nicotine and benzo(a)pyrene in ferroptosis of lung adenocarcinoma and lung squamous cell carcinoma

Tobacco Induced Diseases
Introduction The essence of ferroptosis is the accumulation of membrane lipid peroxides caused by increased iron, which disrupts the redox balance within cells and triggers cell death.
Min G. Wen, Hui X. Zheng, Ying Z. Zhao, Pu Xia   +3 more
doaj   +1 more source

Gene expression patterns unveil a new level of molecular heterogeneity in colorectal cancer. [PDF]

, 2013
The recognition that colorectal cancer (CRC) is a heterogeneous disease in terms of clinical behaviour and response to therapy translates into an urgent need for robust molecular disease subclassifiers that can explain this heterogeneity beyond current ...
Bosman, F., Budinska, E., D'Ario, G., Delorenzi, M., Di Narzo, A.F., Hodgson, J.G., Lapique, N., Popovici, V., Roth, A., Sikora, K.O., Tejpar, S., Weinrich, S., Yan, P.   +12 more
core   +2 more sources

Cordyceps sinensis (CS) Alleviates Chronic Obstructive Pulmonary Disease Symptoms (COPD) by Targeting Inflammation, Apoptosis, and Oxidative Stress Through Ingredient–Gene–Disease Interaction

Immunity, Inflammation and Disease, Volume 13, Issue 12, December 2025.
Our findings indicate that Cordyceps Sinensis (CS) alleviates COPD symptoms by inhibiting inflammation and oxidative stress, with key biomarkers such as interleukins (ILs), tumor necrosis factor (TNF), and reactive oxygen species (ROS) identified. Activating autophagy serves as a protective mechanism against COPD development induced by oxidative stress.
Zirui Zang, Yuhan Kong, Qi Kong
wiley   +1 more source

Predictive toxicology using systemic biology and liver microfluidic "on chip" approaches: Application to acetaminophen injury [PDF]

, 2012
International audienceWe have analyzed transcriptomic, proteomic and metabolomic profiles of hepatoma cells cultivated inside a microfluidic biochip with or without acetaminophen (APAP). Without APAP, the results show an adaptive cellular response to the
Aninat, Caroline, Bois, Frédéric Y., Brochot, Céline, Bunescu, Andrei, Corlu, Anne, Dumas, Marc-Emmanuel, Elena-Herrmann, Bénédicte, Griscom, Laurent, Leclerc, Eric, Legallais, Cécile, Prot, Jean-Matthieu, Razan, Florence, Snouber, Leila Choucha   +12 more
core   +4 more sources

Distinctive metabolic disturbances associated with redox homeostasis, nervous and hormonal functions during gut microbial enrichment upon polystyrene microplastic exposure

iMetaOmics, Volume 2, Issue 4, December 2025.
Microplastic‐induced gut microbial enrichment was dominated by bacteria within Eubacteriales, correlated with the virome, and accompanied by colitis. The polyamine synthetic pathway was activated to maintain glutathionylspermidine homeostasis, concurrent with decreases in pathways involved in the production of energy and reactive oxygen species under ...
Guozhu Ye, Zeming Wu, Guoyou Chen, Xuyi Liu, Yifang Duan, Minghui Li, Qiansheng Huang   +6 more
wiley   +1 more source

Survival of adult neurons lacking cholesterol synthesis in vivo

BMC Neuroscience, 2007
Background Cholesterol, an essential component of all mammalian plasma membranes, is highly enriched in the brain. Both during development and in the adult, brain cholesterol is derived from local cholesterol synthesis and not taken up from the ...
Möbius Wiebke, Xiao Le, Saher Gesine, Fünfschilling Ursula, Nave Klaus-Armin   +4 more
doaj   +1 more source

Dietary Cholesterol Supplementation Inhibits the Steroid Biosynthesis but Does Not Affect the Cholesterol Transport in Two Marine Teleosts: A Hepatic Transcriptome Study

Aquaculture Nutrition, 2023
Cholesterol has been used as additive in fish feeds due to the reduced use of fish meal and fish oil. In order to evaluate the effects of dietary cholesterol supplementation (D-CHO-S) on fish physiology, a liver transcriptome analysis was performed ...
Ziling Song, Haiyan Xiong, Xiaoxue Meng, Qiang Ma, Yuliang Wei, Yanlu Li, Jian Liu, Mengqing Liang, Houguo Xu   +8 more
doaj   +1 more source

Vitamin D related genes in lung development and asthma pathogenesis [PDF]

, 2014
Background: Poor maternal vitamin D intake is a risk factor for subsequent childhood asthma, suggesting that in utero changes related to vitamin D responsive genes might play a crucial role in later disease susceptibility.
Anderson, Chris, Gaedigk, Roger, Kho, Alvin T, Klanderman, Barbara, Leeder, James S, Niu, Simin, Qiu, Weiliang, Sharma, Sunita, Tantisira, Kelan G, Weiss, Scott T   +9 more
core   +1 more source