Results 11 to 20 of about 3,360 (198)

Regions involved in fengycin synthetases enzyme complex formation [PDF]

Journal of Microbiology, Immunology and Infection, 2017
Background: Fengycin is a lipopeptide antibiotic synthesized nonribosomally by five fengycin synthetases. These enzymes are linked in a specific order to form the complex. This study investigates how these enzymes interact in the complex and analyzes the
Yu-Chieh Cheng, Wan-Ju Ke, Shih-Tung Liu
doaj   +4 more sources

Fengycin A Analogues with Enhanced Chemical Stability and Antifungal Properties [PDF]

Organic Letters, 2021
Fengycins are cyclic lipo-depsipeptides produced by Bacillus spp. that display potent antifungal properties but are chemically unstable. This instability has meant that no total synthesis of any fengycin has been published. Here we report the synthesis of fengycin A analogues that display enhanced antifungal properties and chemical stability under both
Diana Gimenez, Aoife Phelan, Cormac D. Murphy, Steven L. Cobb   +3 more
openaire   +6 more sources

Fengycin interaction with lipid monolayers at the air–aqueous interface—implications for the effect of fengycin on biological membranes

Journal of Colloid and Interface Science, 2005
In this study, we investigated the interaction of fengycin, a lipopeptide produced by Bacillus subtilis, with lipid monolayers using the Langmuir trough technique in combination with Brewster angle microscopy. Thermodynamic analyses were performed to get further information about the mixing behavior and the molecular interactions between the two ...
Deleu, Magali, Paquot, Michel, Nylander, T.   +2 more
core   +5 more sources

Analysis of calcium-induced effects on the conformation of fengycin [PDF]

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2013
Fengycin is a natural lipopeptide with antifungal and eliciting properties and able to inhibit the activity of phospholipase A2. A combination of CD, FT-IR, NMR and fluorescence spectroscopic techniques was applied to elucidate its conformation in a membrane-mimicking environment and to investigate the effect of calcium ions on it.
Nasir, Mehmet Nail, Laurent, Pascal, Flore, Christelle, Lins, Laurence, Ongena, Marc, Deleu, Magali   +5 more
openaire   +4 more sources

Fengycin or plipastatin? A confusing question in Bacilli

BioTechnologia, 2019
According to most of the related literature published since their discovery in 1986, fengycin and plipastatin are very related molecules. These are lipodecapeptides encoded by operons of five synthetase genes.
Walaa Hussein
doaj   +2 more sources

Purification, Biochemical Characterization and Self-assembled Structure of a Fengycin-like Antifungal Peptide from Bacillus thuringiensis strain SM1

Frontiers in Microbiology, 2013
An antifungal lipopeptide fengycin, producing strain SM1 was isolated from farm land soil sample and identified as Bacillus thuringienesis strain SM1 by using 16S rDNA analysis. Fengycin detected in the culture extract was further purified using HPLC and
Anupam eRoy, Denial eMahata, Debarati ePaul, Suresh eKorpole, Octavio L Franco, Santi M. Mandal   +5 more
doaj   +2 more sources

Endophytes as source of polypeptide and polyketide antibiotics fengycin and bacillaene [PDF]

, 2018
Endophytische Bakterien besiedeln innere Pflanzengewebe und können physiologische Prozesse in den Pflanzen beeinflussen. Außerdem haben viele Endophyten antibiotische Wirkung gegen Phytopathogene. Damit stellen sie eine umweltfreundliche Alternative zu den chemischen Pestiziden dar und können als biologische Pflanzenschutzmittel eingesetzt werden.
Glazyrina, Julia
core   +3 more sources

Influence of Global Regulatory Factors on Fengycin Synthesis by Bacillus amyloliquefaciens TF28

Fermentation
Fengycin, a lipopeptide synthesized by Bacillus species, exhibits pronounced antifungal activity; however, its low production titer remains a primary constraint to broader application.
Gengxuan Yan, Lu Zhou, Yan Xu, Haihua Xia, Yuan Tian, Chong Yu   +5 more
doaj   +2 more sources

Strategies for improving fengycin production: a review

Microbial Cell Factories
Fengycin is an important member of the lipopeptide family with a wide range of applications in the agricultural, food, medical and cosmetic industries. However, its commercial application is severely hindered by low productivity and high cost. Therefore,
Ying Yin, Xin Wang, Pengsheng Zhang, Pan Wang, Jianping Wen   +4 more
doaj   +3 more sources

Selectivity and Mechanism of Fengycin, an Antimicrobial Lipopeptide, from Molecular Dynamics [PDF]

The Journal of Physical Chemistry B, 2018
Fengycin is a cyclic lipopeptide used as an agricultural fungicide. It is synthesized by Bacillus subtilis as an immune response against fungal infection and functions by damaging the target's cell membrane. Previous molecular dynamics simulations and experiments have led to the hypothesis that the aggregation of fengycins on the membrane surface plays
Sreyoshi Sur, Tod D. Romo, Alan Grossfield   +2 more
core   +4 more sources