Results 11 to 20 of about 18,150,697 (227)
Modern concepts of the fibrinolytic system [PDF]
E3S Web of Conferences, 2020 Among all medical pathologies, cardiovascular diseases are the most dangerous and deadly. On the one hand, thrombosis is a natural reaction of a person to damage to blood vessels, on the other hand, thrombosis is often the cause of death in the event of ...
Sorokin Sergei +2 more
doaj +2 more sources
The Plasminogen (Fibrinolytic) System
Thrombosis and Haemostasis, 1999 IntroductionThe plasminogen (fibrinolytic) system (Fig. 1) comprises an inactive proenzyme, plasminogen, that can be converted to the active enzyme, plasmin. Plasmin degrades fibrin and activates matrix metalloproteinases (MMPs) that, in turn, degrade the extracellular matrix (ECM).1-3 Two physiological plasminogen activators (PAs) have been identified:
Désiré Collen
openaire +3 more sources
Effect of fibrin degradation products on fibrinolytic process [PDF]
The Ukrainian Biochemical Journal, 2016 Fibrin clot lysis by plasminogen/plasmin system results in fibrin degradation products formation with subsequent release into bloodstream. The fragments contain specific binding sites for fibrinolytic system components and can interact with them. In this
T. A. Yatsenko +4 more
doaj +3 more sources
Extraction of Fibrinolytic Proteases From Streptomyces sp. DPUA1576 Using PEG-Phosphate Aqueous Two-Phase Systems [PDF]
Fluid Phase Equilibria, 2013 Extraction of fibrinolytic protease from Streptomyces sp. DPUA1576 fermentation broth was performed using polyethylene glycol (PEG) – phosphate salts aqueous two phase system (ATPS).
Ana Lucia Figueiredo Porto +2 more
exaly +2 more sources
Fibrinolytic System and Cancer: Diagnostic and Therapeutic Applications. [PDF]
Int J Mol Sci, 2021 Fibrinolysis is a crucial physiological process that helps to maintain a hemostatic balance by counteracting excessive thrombosis. The components of the fibrinolytic system are well established and are associated with a wide array of physiological and ...
Mahmood N, Rabbani SA.
europepmc +2 more sources
Fibrinolytic or not : case series of stemi and deadly hemorrhagic stroke [PDF]
Jurnal Profesi Medika, 2020 Cardiovascular diseases (CVD) like myocardial infraction (MI) is still becoming the leading cause of morbidity and mortality and major problem in our healthcare system. Nowadays, revolution in high-tech medical treatment alongside with well-trained staff
Sidhi Laksono Purwowiyoto +1 more
doaj +2 more sources
The Fibrinolytic System and Its Measurement: History, Current Uses and Future Directions for Diagnosis and Treatment. [PDF]
Int J Mol Sci, 2023 The fibrinolytic system is a key player in keeping the haemostatic balance, and changes in fibrinolytic capacity can lead to both bleeding-related and thrombosis-related disorders.
Hvas CL, Larsen JB.
europepmc +2 more sources
Al-Azhar Assiut Medical Journal, 2023 Background The study investigates the relationship between Plasminogen activator inhibitor-1 (PAI-1) levels and the progression of diabetic nephropathy (DN).
El-Saeid M.E.-S. El-Bawab +3 more
doaj +1 more source
Fibrinolytics: from the thrombolysis to the processes of blood vessels growth and remodeling, neurogenesis, carcinogenesis and fibrosis [PDF]
Терапевтический архив, 2019 One of the most outstanding scientific achievements in the thrombolysis is the development and administration of fibrinolysin - the first Soviet drug that lyses blood clots.
V A Tkachuk +7 more
doaj +1 more source
Frontiers in Physiology, 2020 The fibrinolytic system is critical during the onset of fibrinolysis, a fundamental mechanism for fibrin degradation. Both tissue plasminogen activator (tPA) and urokinase plasminogen activator (uPA) trigger fibrinolysis, leading to proteolytic ...
Pamela Carmona +7 more
doaj +1 more source